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Recent and updated pharmacotherapy of migraine

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Abstract

Migraine is a complex and still debatable neurovascular disorder that is on the rise globally, affecting patients of all ages. Various drugs are available for acute and chronic management, but migraine appears to be a chronic and progressive condition, with 5.1% of patients ultimately becoming refractory to drugs. For the acute and preventative management of migraine, newer molecules targeting calcitonin gene-related peptide (CGRP) have been approved and others are in various phases of development. This narrative review aims to give an overview of migraine therapy with special emphasis on CGRP and the molecules targeting this that are either approved or have completed phase III trials.

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Singh, A., Thangaraju, P. & Dhaneria, S. Recent and updated pharmacotherapy of migraine. Drugs Ther Perspect 35, 571–578 (2019). https://doi.org/10.1007/s40267-019-00664-2

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