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Pacemakers—A journey through the years

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Indian Journal of Thoracic and Cardiovascular Surgery Aims and scope Submit manuscript

Abstract

This is an article on the history of artificial cardiac pacemakers. Before the advent of pacemakers, not much could be done for patients who suffered from cardiac asystole and other cardiac rhythm disturbances. Although the concept that an artificial pacemaker could be used to stimulate the heart in standstill evolved much earlier, it was not until 1952 that the first case of successful pacing of the human heart could be documented. From that time onwards, pacemakers have seen tremendous technological advancements—not only in terms of pacemaker efficacy, but also in terms of patient safety. The outstanding amongst these include the development of myocardial and endocardial electrodes and the invention of a transistorized external pacemaker with a battery backup. With the development of the first implantable pacemaker, the cherished dream of long term pacing came true. At the same time, recognition of pacemaker induced arrhythmias gave an impetus to the evolution of safer modes for cardiac pacing.

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References

  1. Hyman AS. Resuscitation of the stopped heart by intracardial therapy II. Experimental use of an artificial pacemaker. Arch Intern Med 1932; 50: 283–05.

    Google Scholar 

  2. Cook L. Recovery after massage of the heart. Brit Med J 1926; 2: 1118.

    Google Scholar 

  3. Hyman AS. Resuscitation of the stopped heart by intracardiac therapy. Arch Intern Med 1930; 46: 553–68.

    Google Scholar 

  4. Furman S, Jeffrey K, Szarka G. The mysterious fate of Hyman's Pacemaker. Pacing Clin Electrophysiol 2001; 24: 1126–37.

    Article  PubMed  CAS  Google Scholar 

  5. Bigelow WG, Callaghan JC, Hopps JA. General hypothermia for experimental intracardiac surgery: the use of electrophrenic respiration, an artificial pacemaker for cardiac standstill, and radiofrequency rewarming for general hypothermia. Ann Surg 1950; 132: 531–39.

    Article  PubMed  CAS  Google Scholar 

  6. Callaghan JC, Bigelow WG. An electrical artificial pacemaker for standstill of the heart. Ann Surg 1951; 134: 8–17.

    Article  PubMed  CAS  Google Scholar 

  7. Furman S. The early history of cardiac pacing. Pacing Clin Electrophysiol 2003; 26: 2023–32.

    Article  PubMed  Google Scholar 

  8. Hopps JA, Bigelow WG. Electrical Treatment of Cardiac arrest: A cardiac stimulator-defibrillator. Surgery 1954; 36: 833–49.

    PubMed  CAS  Google Scholar 

  9. Zoll PM. Resuscitation of the heart in ventricular standstill by external electric stimulation. N Engl J Med 1952; 247: 768–71.

    Article  PubMed  CAS  Google Scholar 

  10. Zoll PM, Linenthal AJ, Norman LR, Paul MH, Gibson W. Treatment of unexpected cardiac arrest by external electric stimulation of the heart. N Engl J Med 1956; 254: 541–46.

    Article  PubMed  CAS  Google Scholar 

  11. Cook P, Davies JG, Leatham A. External electric stimulation for treatment of ventricular standstill. Lancet 1956; 271: 1185–89.

    PubMed  CAS  Google Scholar 

  12. Zoll PM, Linenthal AJ, Norman LR, Paul MH, Gibson W. External electric stimulation of the heart in cardiac arrest. Arch Intern Med 1955; 96: 639–53.

    CAS  Google Scholar 

  13. Gibson W, Linenthal AJ, Norman LR, Paul MH, Zoll PM. The effect of External electric currents on heart: control of cardiac rhythm and induction and termination of cardiac arrhythmias. Circulation 1956; 14: 745–56.

    PubMed  CAS  Google Scholar 

  14. Weirich WL, Gott VL, Lillehei CW. The treatment of complete heart block by the combined use of a myocardial electrode and an artificial pacemaker. Surg Forum 1957; 8: 360–363.

    PubMed  CAS  Google Scholar 

  15. Lillehei CW, Gott VL, Hodges PC Jr, Long DM, Bakken EE. Transistor pacemaker for treatment of complete atrioventricular dissociation. J Am Med Assoc 1960; 172: 2006–10.

    CAS  PubMed  Google Scholar 

  16. Furman S, Schwedel JB. An intracardiac pacemaker for Stokes Adams seizures. N Engl J Med 1959; 261: 943–48.

    Article  PubMed  CAS  Google Scholar 

  17. Furman S, Escher DJ, Schwedel JB, Solomon N. Transvenous pacing. A seven year review. Am Heart J 1966; 71: 408–16.

    Article  PubMed  CAS  Google Scholar 

  18. Schwedel JB, Furman S, Escher DJ. Use of an intracardiac pacemaker in the treatment of Stokes Adams seizures. Prog Cardiovasc Dis 1960; 3: 170–77.

    Article  PubMed  CAS  Google Scholar 

  19. Larsson B, Elmqvist H, Ryden L, Schuller H. Lessons from the first patient with an implanted pacemaker: 1958–2001. Pacing Clin Electrophysiol 2003: 26: 114–24.

    Article  PubMed  Google Scholar 

  20. Elmqvist R. Review of early pacemaker development. Pacing Clin Electrophysiol 1978; 1: 535–36.

    Article  PubMed  CAS  Google Scholar 

  21. Senning A. Discussion of paper by Stephenson. J Thorac Surg 1959; 38: 639.

    Google Scholar 

  22. Fiandra O. The first pacemaker implant in America. Pacing Clin Electrophysiol. 1988; 11: 1234–38.

    Article  PubMed  CAS  Google Scholar 

  23. Glenn WW, Mauro A, Longo E, Lavietes PH, Mackay FJ. Remote stimulation of the heart by radiofrequency stimulation. N Engl J Med 1959; 261: 948–51.

    Article  PubMed  CAS  Google Scholar 

  24. Chardack WM, Gage AA, Greatbatch W. A transistorized, self-contained, implantable pacemaker for the long term correction of complete heart block. Surgery 1960; 48: 643–54.

    PubMed  CAS  Google Scholar 

  25. Hunter SW, Roth NA, Bernardez D, Noble JL. A bipolar myocardial electrode for complete heart block. Lancet 1959; 79: 506–08.

    CAS  Google Scholar 

  26. Lagergren H, Johansson L, Landegren J, Edhag O. One hundred cases of treatment for Adams Stokes syndrome with permanent intravenous pacemaker. J Thorac Cardiovasc Surg 1965; 50: 710–14.

    PubMed  CAS  Google Scholar 

  27. Lagergren H, Johansson L. Intracardiac stimulator for complete heart block. Acta Chir Scandinavia 1963; 125: 562–66.

    CAS  Google Scholar 

  28. Salkind AJ, Raddi W. Primary and secondary cells. Ann N Y Acad Sci 1969; 167: 635–44.

    Article  PubMed  CAS  Google Scholar 

  29. Huffman FN, Norman JC. Nuclear-fuelled cardiac pacemakers. Chest 1974; 65: 667–71.

    Article  PubMed  CAS  Google Scholar 

  30. Ruben S. Sealed zinc-mercury oxide cells for implantable cardiac pacemakers. Ann N Y Acad Sci 1969; 167: 627–34.

    Article  PubMed  CAS  Google Scholar 

  31. Parsonnet V, Berstein AD, Perry GY. The nuclear pacemaker: Is renewed interst warranted? Am J Cardiol 1990; 66: 837–42.

    Article  PubMed  CAS  Google Scholar 

  32. Burr LH. Lithium lodide cardiac pacemaker: initial clinical experience. Canad Med Assoc J 1976; 115: 765–66.

    PubMed  CAS  Google Scholar 

  33. Kantrowitz A, Cohen R, Raillard H, Schmidt J, Feldman DS. The treatment of complete heart block with an implanted controllable pacemaker. Surg Gynecol Obstet 1962; 115: 415–20.

    PubMed  CAS  Google Scholar 

  34. Furman S. The early history of cardiac pacing. Pacing Clin Electrophysiol 2003; 26: 2023–32.

    Article  PubMed  Google Scholar 

  35. Lown B, Kosowsky BD. Artificial cardiac pacemakers-III. N Engl J Med 1970; 283: 1023–31.

    Article  PubMed  CAS  Google Scholar 

  36. Bayliss CE, Beanlands DS, Baird RJ. The Pacemaker-Twiddler's Syndrome. Canad Med Assoc J 1968; 99: 371–73.

    PubMed  CAS  Google Scholar 

  37. Wallace WA, Abelmann WH, Norman JC. Runaway demand pacemaker. Ann Thorac Surg 1970; 9: 209–20.

    Article  PubMed  CAS  Google Scholar 

  38. Khalilullah M, Khanna SK, Gupta U, Padmavati S. Pacemaker Twiddler's Syndrome. J Cardiovasc Surg 1979; 20: 95–100.

    CAS  Google Scholar 

  39. Been M, Darke PG. Pacemaker twiddler: A twist in the tail? Brit Med J 1988; 297: 1642–43.

    Article  PubMed  CAS  Google Scholar 

  40. Judson JP, Glenn WW, Holcomb WG. Cardiac pacemakers. J Surg Res 1967; 7: 527–44.

    Article  PubMed  CAS  Google Scholar 

  41. Bilitch M, Cosby RS, Cafferky EA. Ventricular fibrillation and competitive pacing. N Engl J Med 1967; 276: 598–04.

    Article  PubMed  CAS  Google Scholar 

  42. Escher DJ. The present status of clinical cardiac pacing. Am Heart J 1967; 74: 126–32.

    Article  PubMed  CAS  Google Scholar 

  43. Lown B, Kosowsky BD. Artificial cardiac pacemakers-I. N Engl J Med 1970; 283: 907–16.

    Article  PubMed  CAS  Google Scholar 

  44. Mitchell JH, Gilmore JP, Sarnoff SJ. The transport function of the atrium. Am J Cardiol 1962; 9: 237–47.

    Article  PubMed  CAS  Google Scholar 

  45. Sowton E. Artificial pacemaking and sinus rhythm. Br Heart J 1965; 27: 311–18.

    Article  PubMed  CAS  Google Scholar 

  46. Nathan DA, Center S, Wu CY, Keller W. An implantable, synchronous pacemaker for the long term correction of complete heart block. Am J Cardiol 1963; 11: 362–67.

    Article  PubMed  CAS  Google Scholar 

  47. Escher DJ. The present status of clinical cardiac pacing. Am Heart J 1967; 74: 126–32.

    Article  PubMed  CAS  Google Scholar 

  48. Berkovits BV. Demand pacing. Ann N Y Acad Sci. 1969; 167: 891–95.

    Article  PubMed  CAS  Google Scholar 

  49. Lemberg L, Castellanos A Jr, Berkovits BV. Pacemaking on demand in AV block. J Am Med Assoc 1965; 191: 12–14.

    CAS  Google Scholar 

  50. Castillo CA, Berkovits BV, Castellanos A Jr, Lemberg L, Callard G, Jude JR. Bifocal demand pacing. Chest 1971; 59: 360–64.

    Article  PubMed  CAS  Google Scholar 

  51. Parsonnet V, Furman S, Smyth NP. Implantable cardiac pacemakers: Status report and resource guideline. Circulation 1974; 50: A21–35.

    PubMed  CAS  Google Scholar 

  52. Parsonnet V, Furman S, Smyth NP. A revised code for pacemaker identification. Pacing Clin Electrophysiol 1981; 4: 400–03.

    Article  PubMed  CAS  Google Scholar 

  53. Bernstein AD, Daubert JC, Fletcher RD, Hayes DL, Luderitz B, Reynolds DW. The Revised NASPE/BPEG Generic Code for antibradycardia, adaptive-rate, and multisite pacing. Pacing Clin Electrophysiol 2002; 25: 260–64.

    Article  PubMed  Google Scholar 

  54. Sowton E, Leatham A, Carson P. The suppression of arrhythmias by artificial pacing. Lancet 1964; 13: 1098–100.

    Article  Google Scholar 

  55. Haft JI, Kosowsky BD, Lau SH, Stein E, Damato AN. Termination of atrial flutter by rapid electrical pacing of the atrium. Am J of Cardiol 1967; 20: 239–44.

    Article  CAS  Google Scholar 

  56. Bennett MA, Pentecost BL. Reversion of ventricular tachycardia by pacemaker stimulation. Brit Heart J 1971; 33: 922–27.

    Article  PubMed  CAS  Google Scholar 

  57. Ryan GF, Easley RM Jr, Zaroff LI, Goldstein S. Paradoxical use of a demand pacemaker in treatment of supraventricular tachycardia due to Wolff-Parkinson-White Syndrome. Circulation 1968; 38: 1037–43.

    PubMed  CAS  Google Scholar 

  58. Khalilullah M, Mendes TA, Mathur VS, Roy SB. Use of indigenous pacemaker in the treatment of complete heart block. J Indian Med Assoc 1970; 55: 119–22.

    PubMed  CAS  Google Scholar 

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Correspondence to Tarun Mittal.

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Mittal, T. Pacemakers—A journey through the years. Indian J Thorac Cardiovasc Surg 21, 236–249 (2005). https://doi.org/10.1007/s12055-005-0060-0

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  • DOI: https://doi.org/10.1007/s12055-005-0060-0

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