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Traitement médicamenteux des douleurs neuropathiques périphériques : recommandations d’un groupe d’experts pour le Maghreb francophone

Pharmacological treatment of peripheral neuropathic pain: expert panel recommendations for the French-speaking maghrebian region

  • Recommandations / Recommendations
  • Published:
Douleur et Analgésie

Résumé

Les douleurs neuropathiques périphériques (DN) ont fait l’objet de nombreuses recherches fondamentales et cliniques au cours des 20 dernières années. Ces travaux ont conduit à une meilleure compréhension de leur physiopathologie, au développement de nouvelles thérapeutiques, puis à la publication de recommandations pour leur diagnostic et leur traitement. Ces recommandations concernent essentiellement la prise en charge des patients européens et nord-américains, et aucune recommandation n’est disponible pour le traitement des DN dans la région du Maghreb francophone alors que cette région arbore des spécificités en termes de prévalence des pathologies causales des DN et des comorbidités. C’est la raison pour laquelle un groupe interdisciplinaire d’experts de l’Algérie, du Maroc et de la Tunisie s’est réuni pour élaborer, à partir des données déjà publiées et en tenant compte des particularités de leur pays respectif, des recommandations spécifiques pour la prise en charge pharmacologique des DN.

Abstract

Peripheral neuropathic pain (NeP) has been a major theme of basic and clinical research over the past 20 years. Extensive research has led to an increased knowledge of underlying pathophysiological mechanisms, the development of new therapeutic agents, and the publication of treatment guidelines. Nonetheless, a significant gap in the treatment guideline literature appears to be the exclusive focus on recommendations for managing NeP patients in North America and Europe. To date there are no guidelines for NeP in the French-speaking North-African countries (Algeria, Tunisia, Morocco), while these countries display several specificities in terms of aetiologies of NeP and comorbidities. A multidisciplinary panel of experts met to reach a consensus on how best to apply evidence-based guidelines for the treatment of NeP in this region of the world. From the so far published guidelines, they propose recommendations for the pharmacological management of NeP in their countries.

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Références

  1. Attal N, Cruccu G, Haanpää M, et al (2006) EFNS guidelines on pharmacological treatment of neuropathic pain. Eur J Neurol 13:1153–1169

    Article  PubMed  CAS  Google Scholar 

  2. Attal N, Fermanian C, Fermanian J, et al (2008) Neuropathic pain: are there distinct subtypes depending on the aetiology or anatomical lesion? Pain 138:343–353

    Article  PubMed  CAS  Google Scholar 

  3. Bockbrader HN, Radulovic LL, Posvar EL, et al (2010) Clinical pharmacokinetics of pregabalin in healthy volunteers. J Clin Pharmacol 50:941–950

    Article  PubMed  CAS  Google Scholar 

  4. Bohlega S, Alsaadi T, Amir A, et al (2010) Guidelines for the pharmacological treatment of peripheral neuropathic pain: expert panel recommendations for the middle East region. J Int Med Res 38:295–317

    PubMed  CAS  Google Scholar 

  5. Chalk C, Benstead TJ, Moore F (2007) Aldose reductase inhibitors for the treatment of diabetic polyneuropathy. Cochrane Database Syst Rev 4:CD004572

    Google Scholar 

  6. Danzon PM, Epstein AJ (2008) Effects of regulation on drug launch and pricing in interdependent markets. National Bureau of Economic Research (NBER) Working Paper no 14041, May

  7. Duehmke RM, Hollingshead J, Cornblath DR (2006) Tramadol for neuropathic pain. Cochrane Database Syst Rev 3:CD003726

    Google Scholar 

  8. Dworkin RH, O’Connor AB, Backonja M, et al (2007) Pharmacologic management of neuropathic pain: evidence-based recommendations. Pain 132:237–251

    Article  PubMed  CAS  Google Scholar 

  9. Eisenberg E, McNicol ED, Carr DB (2006) Opioids for neuropathic pain. Cochrane Database Syst Rev 3:CD006146

    Google Scholar 

  10. Finnerup NB, Otto M, McQuay HJ, et al (2005) Algorithm for neuropathic pain treatment: an evidence based proposal. Pain 118:289–305

    Article  PubMed  CAS  Google Scholar 

  11. Freynhagen R, Bennett MI (2009) Diagnosis and management of neuropathic pain. BMJ 339:b3002

    Article  PubMed  CAS  Google Scholar 

  12. Green CR, Anderson KO, Baker TA, et al (2003) The unequal burden of pain: confronting racial and ethnic disparities in pain. Pain Med 4:277–294

    Article  PubMed  Google Scholar 

  13. Martinez V, Attal N, Bouhassira D, et al (2010) Les douleurs neuropathiques chroniques: diagnostic, évaluation et traitement en médecine ambulatoire.Recommandations pour la pratique clinique de la Société française d’étude et de traitement de la douleur. Douleurs 11:3–21

    Google Scholar 

  14. Mintzer J, Burns A (2000) Anticholinergic side-effects of drugs in elderly people. J R Soc Med 93:457–462

    PubMed  CAS  Google Scholar 

  15. Moore AR, O’Keefe ST (1999) Drug-induced cognitive impairment in the elderly. Drugs Aging 15:15–28

    Article  PubMed  CAS  Google Scholar 

  16. Moore RA, Straube S, Wiffen PJ, et al (2009) Pregabalin for acute and chronic pain in adults. Cochrane Database Syst Rev 3:CD007076

    Google Scholar 

  17. Moulin DE, Clark AJ, Gilron I, et al (2007) Pharmacological management of chronic neuropathic pain — consensus statement and guidelines from the Canadian Pain Society. Pain Res Manag 12:13–21

    PubMed  CAS  Google Scholar 

  18. O’Connor AB, Dworkin RH (2009) Treatment of neuropathic pain: an overview of recent guidelines. Am J Med 122:S22–S32

    Article  PubMed  Google Scholar 

  19. Rascati K (ed) (2008) Essentials of pharmacoeconomics. Lippincott Williams & Wilkins, Philadelphia

    Google Scholar 

  20. Rodríguez MJ, Díaz S, Vera-Llonch M, et al (2007) Cost-effectiveness analysis of pregabalin versus gabapentin in the management of neuropathic pain due to diabetic polyneuropathy or post-herpetic neuralgia. Curr Med Res Opin 23:2585–2596

    Article  PubMed  Google Scholar 

  21. Rollason V, Samer C, Piguet V, et al (2008) Pharmacogenetics of analgesics: toward the individualisation of prescription. Pharmacogenomics 7:905–933

    Article  Google Scholar 

  22. Saarto T, Wiffen PJ (2007) Antidepressants for neuropathic pain. Cochrane Database Syst Rev 4:CD005454

    Google Scholar 

  23. Smith T, Nicholson RA (2007) Review of duloxetine in the management of diabetic peripheral neuropathic pain. Vasc Health Risk Manag 3:833–844

    PubMed  CAS  Google Scholar 

  24. Sommer BR, Fenn H, Pompei P, et al (2003) Safety of antidepressants in the elderly. Expert Opin Drug Saf 2:367–383

    Article  PubMed  CAS  Google Scholar 

  25. Spina E, Scordo MG (2002) Clinically significant drug interactions with antidepressants in the elderly. Drugs Aging 19:299–320

    Article  PubMed  CAS  Google Scholar 

  26. Tarride JE, Gordon A, Vera-Llonch M, et al (2006) Cost-effectiveness of pregabalin for the management of neuropathic pain associated with diabetic peripheral neuropathy and postherpetic neuralgia: a Canadian perspective. Clin Ther 28:1922–1934

    Article  PubMed  CAS  Google Scholar 

  27. Treede RD, Jensen TS, Campbell JN, et al (2008) Neuropathic pain: redefinition and a grading system for clinical and research purposes. Neurology 70:1630–1635

    Article  PubMed  CAS  Google Scholar 

  28. Wiffen PJ, McQuay HJ, Moore RA (2005) Carbamazepine for acute and chronic pain in adults. Cochrane Database Syst Rev 3:CD005451

  29. Wiffen PJ, McQuay HJ, Rees J, et al (2005) Gabapentin for acute and chronic pain. Cochrane Database Syst Rev 3:CD005452

  30. Wiffen PJ, Rees J (2007) Lamotrigine for acute and chronic pain. Cochrane Database Syst Rev 2:CD006044

    Google Scholar 

  31. Wong IC, Besag FM, Santosh PJ, et al (2004) Use of selective serotonin reuptake inhibitors in children and adolescents. Drug Saf 27:991–1000

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Service d’anesthésie-réanimation, centre de traitement de la douleur d’Alger, Société algérienne d’évaluation et de traitement de la douleur (SAETD), centre Pierre-et-Marie-Curie, établissement hospitalier spécialisé (EHS), place du 1er-Mai, avenue Battandier, Alger, 16021, Algérie

    B. Griene

  2. Service de rhumatologie, faculté de médecine de Sousse, CHU Farhat-Hached, avenue Ibn-Eljazzar, 4000, Sousse, Tunisie

    E. Bouajina

  3. Service de neurologie, centre de traitement de la douleur, hôpital La-Rabta, 1007, Bab-Saadoun, Tunis

    M. Haddad

  4. Service de rhumatologie, EHS appareil locomoteur, hôpital Ben-Aknoun-Professeur-A.-Boukhroufa, route des Deux-bassins, Ben-Aknoun, Alger, Algérie

    A. Ladjouze

  5. Service d’endocrinologie-diabétologie, 9, rue Al-Hassan-Azzaafrani (ex Tahure), villa Delice, Casablanca, 20000, Maroc

    F. Marouan

  6. Service d’anesthésie-réanimation-douleur, Centre national douleur et soins palliatifs de Rabat, Institut national d’oncologie, BP 6213, Rabat, Maroc

    M. Nejmi

  7. Service de neurophysiologie clinique, hôpital des spécialités, BP 10080, Rabat, Maroc

    M. R. Ouazzani Taibi

  8. Unité « Consultations et explorations fonctionnelles », service de médecine interne, établissement publique hospitalier (EHS) de Birtraria, El-Biar, Alger, Algérie

    S. Zekri

Authors
  1. B. Griene
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  2. E. Bouajina
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  3. M. Haddad
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  4. A. Ladjouze
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  5. F. Marouan
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  6. M. Nejmi
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  7. M. R. Ouazzani Taibi
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  8. S. Zekri
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Corresponding author

Correspondence to B. Griene.

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Griene, B., Bouajina, E., Haddad, M. et al. Traitement médicamenteux des douleurs neuropathiques périphériques : recommandations d’un groupe d’experts pour le Maghreb francophone. Douleur analg 24, 112–120 (2011). https://doi.org/10.1007/s11724-010-0226-4

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  • DOI: https://doi.org/10.1007/s11724-010-0226-4

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