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Complex between modified β-cyclodextrins and three components of traditional Chinese medicine in supercritical carbon dioxide medium

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Abstract

In this work, the complex between three hydrophobic efficacious components of plants (anisole, asarone, curcumin) and modified cyclodextrin (2-hydroxypropyl-β-cyclodextrin, methyl-β-cyclodextrin) was investigated in supercritical carbon dioxide medium; and compared with the corresponding complex in air circumstance. The effect of the substitute group in the drug molecule on the complex reaction was also discussed.

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Acknowledgments

This study is supported by Molecular Science Center of Institute of Chemistry, The Chinese Academy of Sciences.

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  1. Institute of Chemistry, Chinese Academy of Sciences, The First North Street 2, Zhongguancun, Beijing, 100190, People’s Republic of China

    Jun He

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Correspondence to Jun He.

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He, J. Complex between modified β-cyclodextrins and three components of traditional Chinese medicine in supercritical carbon dioxide medium. J Incl Phenom Macrocycl Chem 68, 399–410 (2010). https://doi.org/10.1007/s10847-010-9799-z

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