Abstract
As a result of the deleterious effects of mycotoxins on human and animal health, and the consequently increasing stringency in the determination of food contamination levels, many researchers have focused their efforts on developing new devices for the detection of these compounds. Biosensors merit special mention due to their sensitivity, accuracy, cost-effectiveness and simplicity, not only of the construction, but also of the sample pre-treatment, if necessary, and the measurement step. Furthermore, biosensor arrays offer additional advantages, such as the possibility to measure multiple samples and provide multi-mycotoxin profiles in one assay. In this case, apart from shortening the analysis time, accuracy is improved by the assessment of matrix interferences and synergistic effects among mycotoxins. Biosensors and arrays for mycotoxins are thus promising biotechnological tools for mycotoxin detection in food.
Graphical Abstract
Similar content being viewed by others
References
Basic food safety for health workers (1999) WHO
Nabok AV, Tsargorodskaya A, Holloway A, Starodub NF, Gojster O (2007) Biosens Bioelectron 22:885
Tsai W-C, Hsieh C-K (2007) Anal Lett 40:1979
Paepens C, Saeger SD, Sibanda L, Barna-Vetró I, Léglise I, Van Hove F, Van Peteghem C (2004) Anal Chim Acta 523:229
Kolosova AY, Saeger SD, Eremin SA, Van Peteghem C (2007) Anal Bioanal Chem 387:1095
Schneider E, Curtui V, Seidler C, Dietrich R, Usleber E, Märtlbauer E (2004) Toxicol Lett 153:113
Goryacheva IY, Basova EY, Van Peteghem C, Eremin SA, Pussemier L, Motte J-C, Saeger SD (2008) Anal Bioanal Chem 390:723
Shim W-B, Yang Z-Y, Kim J-S, Kim J-Y, Kang S-J, Wo G-J, Chung Y-C, Eremin SA, Chung D-H (2007) J Microbiol Biotechnol 17(10):1629
Xiulan S, Xiaolian Z, Jian T, Xiaohong G, Jun Z, Chu FS (2006) Food Control 17:256
Delmulle BS, Saeger SD, Sibanda L, Barna-Vetró I, Van Peteghem CH (2005) J Agric Food Chem 53:3364
Ho J-AA, Wauchope RD (2002) Anal Chem 74:1493
Daly SJ, Keating GJ, Dillon PP, Manning BM, O’Kennedy R, Lee HA, Morgan MRA (2000) J Agric Food Chem 48:5097
Schnerr H, Vogel R, Niessen L (2002) Food Agric Immunol 14:313
Tüdös AJ, Lucas-Van Den Bos ER, Stigter ECA (2003) J Agric Food Chem 51:5843
Nabok AV, Tsargorodskaya A, Hassan AK, Starodub NF (2005) Appl Surf Sci 246:381
Mullett W, Lai EPC, Yeung JM (1998) Anal Biochem 258:161
Van der Gaag B, Spath S, Dietrich H, Stigter E, Boonzaaijer G, van Osenbruggen T, Koopal K (2003) Food Control 14:251
Adányi N, Levkovets IA, Rodriguez-Gil S, Ronald A, Váradi M, Szendro I (2007) Biosens Bioelectron 22:797
Grow AE, Wood LL, Claycomb JL, Thompson PA (2003) J Microbiol Methods 53:221
Thompson VS, Maragos CM (1996) J Agric Food Chem 44:1041
Maragos CM, Thompson VS (1999) Nat Toxins 7:371
Ngundi MM, Shriver-Lake LC, Moore MH, Lassman ME, Ligler FS, Taitt CR (2005) Anal Chem 77:148
Ngundi MM, Qadri SA, Wallace EV, Moore MH, Lassman ME, Shriver-Lake LC, Ligler FS, Taitt CR (2006) Environ Sci Technol 40:2352
Sapsford KE, Taitt CR, Fertig S, Moore MH, Lassman ME, Maragos CM, Shriver-Lake LC (2006) Biosens Bioelectron 21:2298
Ngundi MM, Shriver-Lake LC, Moore MH, Ligler FS, Taitt CR (2006) J Food Prot 69:3047
Sapsford KE, Ngundi MM, Moore MH, Lassman ME, Shriver-Lake LC, Taitt CR, Ligler FS (2006) Sensor Actuat B Chem 113:599
Liu Y, Qin Z, Wu X, Jiang H (2006) Biochem Eng J 32:211
Alarcón SH, Palleschi G, Compagnone D, Pascale M, Visconti A, Barna-Vetró I (2006) Talanta 69:1031
Prieto-Simón B, Campàs M, Marty JL, Noguer T (2008) Biosens Bioelectron 23:995
Piermarini S, Micheli L, Ammida NHS, Palleschi G, Moscone D (2007) Biosens Bioelectron 22:1434
Acknowledgments
Dr. Campàs gratefully acknowledges financial support from the Departament d’Educació i Universitats de la Generalitat de Catalunya, through the Beatriu de Pinós Programme. Dr. Prieto-Simón is grateful to the Japan Society for the Promotion of Science for a fellowship supporting her research at the Tokyo University of Technology.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Prieto-Simón, B., Campàs, M. Immunochemical tools for mycotoxin detection in food. Monatsh Chem 140, 915–920 (2009). https://doi.org/10.1007/s00706-009-0133-7
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00706-009-0133-7