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Synthesis and Characterization of Injectable Photocrosslinking Poly (ethylene glycol) Diacrylate based Hydrogels

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Abstract

The poly (ethylene glycol) diacrylate (PEGDA)-based hydrogels were prepared by UV radiation under nitrogen, using PEGDA and 2-hydroxyethyl methacrylate (HEMA) as precursors. The PEGDA and HEMA precursors were respectively added into distilled water at a predetermined feed ratio. 2-Hydroxy-1-[4-(hydroxyethoxy)phenyl]-2-methyl-1-propanone (Irgacure2959) was used as a photoinitiator. The PEGDA-based hydrogels were characterized by FT-IR spectra, interior morphology, equilibrium swelling ratio, and Dynamic contact angle (DCA). The results showed: (1) -C=C- bonds of PEGDA and HEMA disappeared after photocrosslinking, which indicated hydrogel formation by consuming -C=C- bonds; (2) swelling ratio of the hydrogels were greatly influenced by the additive precursor ratios and microporous net; (3) with HEMA content increasing in PEGDA-based hydrogels, equilibrium water content (EWC) increased and the contact angle decreased, which resulted from the strong H-bonding interactions of HEMA between the polymer and water.

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Authors and Affiliations

  1. Institute of Chemical Engineering and Light Industry, Guangdong University of Technology, 510006, Guangdong, PR China

    Guoxin Tan

  2. College of Material Science and Engineering, South China University of Technology, 510641, Guangdong, PR China

    Guoxin Tan, Yingjun Wang & Shujiang Zhang

  3. Key lab of specially functional materials, Ministry of Education, South China University of Technology, 510641, Guangdong, PR China

    Yingjun Wang & Shujiang Zhang

  4. College of Bioengineering, Chongqing Institute of Technology, 400050, Chongqing, PR China

    Jun Li

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  1. Guoxin Tan
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  2. Yingjun Wang
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  3. Jun Li
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  4. Shujiang Zhang
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Correspondence to Guoxin Tan.

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Tan, G., Wang, Y., Li, J. et al. Synthesis and Characterization of Injectable Photocrosslinking Poly (ethylene glycol) Diacrylate based Hydrogels . Polym. Bull. 61, 91–98 (2008). https://doi.org/10.1007/s00289-008-0932-8

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  • DOI: https://doi.org/10.1007/s00289-008-0932-8

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