Abstract
An overview of Toxicity Identification and Evaluation (TIE) procedures, used for the effect-based analysis of endocrine disrupting compounds (EDCs) in environmental samples, is presented. Future trends in advanced chemical analysis of EDCs and some emerging contaminants are outlined. The review also gives an overview of concentration levels found in environmental samples and discusses the correlation of calculated estrogenicity (based on chemical analysis of target EDCs) with that measured by various bioassays.
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Acknowledgements
This work has been supported by the EU Program Copernicus (EXPRESS-IMMUNOTECH) contract Number ICA2-CT-2001-10007, and the Spanish MCyT (PPQ2000-3007-CE). M. Petrovic and M.J. Lopez de Alda acknowledge the "Ramon y Cajal" contract from the Spanish MCyT.
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Petrovic, M., Eljarrat, E., Lopez de Alda, M.J. et al. Endocrine disrupting compounds and other emerging contaminants in the environment: A survey on new monitoring strategies and occurrence data. Anal Bioanal Chem 378, 549–562 (2004). https://doi.org/10.1007/s00216-003-2184-7
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DOI: https://doi.org/10.1007/s00216-003-2184-7