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Small-angle neutron scattering from aqueous mixed colloids of lecithin and bile salt

  • Films, Membranes, Surfaces And Wetting
  • Conference paper
  • First Online:
Trends in Colloid and Interface Science IV

Part of the book series: Progress in Colloid & Polymer Science ((PROGCOLLOID,volume 81))

Abstract

The morphology of particles in the isotropic phases of mixed aqueous colloids of lecithin and glycocholate are studied using small-angle neutron scattering. At the highest concentrations globular mixed micelles are present and have a radius of gyration of 24 Å. At lower concentrations rod-like structures are present. In each and every case the rod radii are about 27 Å. It is proposed that the rods form by aggregation of disk-like micelles about 27 Å radius and height 50 Å. The rods grow larger as the solutions are diluted and appear to associate into loose networks just before the occurrence of a concentration-induced transition to vesicles. The vesicles have walls that are a single lipid bilayer of lecithin and glycocholate.

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Author information

Authors and Affiliations

  1. Los Alamos Neutron Scattering Center, Physics Division, Los Alamos National Laboratory, Los Alamos, New Mexico, USA

    R. P. Hjelm

  2. Intense Neutron Source Division and Chemistry Division, Argonne National Laboratory, USA, Argonne, Illinois

    P. Thiyagaragan

  3. Los Alamos Neutron Scattering Center and Theoretical Division, Los Alamos National Laboratory, Los Alamos, New Mexico, USA

    D. S. Sivia

  4. Institut Laue-Langevin, Grenoble, France

    P. Lindner

  5. Department of Pharmaceutics, University of Illinois at Chicago, Chicago, Illinois, USA

    H. Alkan

  6. Institut für Festkörperforschung, Kernforschungsanlage Jülich/KFA, FRG

    D. Schwahn

Authors
  1. R. P. Hjelm
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  2. P. Thiyagaragan
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  3. D. S. Sivia
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  4. P. Lindner
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  5. H. Alkan
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  6. D. Schwahn
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Editor information

M. Zulauf P. Lindner P. Terech

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© 1990 Dr. Dietrich Steinkopff Verlag GmbH & Co. KG

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Hjelm, R.P., Thiyagaragan, P., Sivia, D.S., Lindner, P., Alkan, H., Schwahn, D. (1990). Small-angle neutron scattering from aqueous mixed colloids of lecithin and bile salt. In: Zulauf, M., Lindner, P., Terech, P. (eds) Trends in Colloid and Interface Science IV. Progress in Colloid & Polymer Science, vol 81. Steinkopff. https://doi.org/10.1007/BFb0115557

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  • DOI: https://doi.org/10.1007/BFb0115557

  • Published:

  • Publisher Name: Steinkopff

  • Print ISBN: 978-3-7985-0839-2

  • Online ISBN: 978-3-7985-1687-8

  • eBook Packages: Springer Book Archive

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