Skip to main content
SpringerLink
Log in

Magnetic and temperature-sensitive composite polymer particles and adsorption behavior of emulsifiers and trypsin

  • Published:
Macromolecular Research Aims and scope Submit manuscript

Abstract

A combination of magnetic and temperature-responsive properties in the same polymer composites is expected to increase their potential applications in the biomedical field. Accordingly, micron-sized magnetite/polystyrene/ poly(2-dimethylaminoethyl methacrylate-ethyleneglycol dimethacrylate), which are abbreviated as Fe3O4/PS/P (DM-EGDM) composite polymer particles, were prepared by the seeded copolymerization of DM and EGDM in the presence of magnetite/polystyrene (Fe3O4/PS) particles. Fe3O4/PS/P(DM-EGDM) composite particles with magnetic properties showed a temperature-sensitive phase transition at approximately 31 °C. The adsorption behavior of the low molecular weight emulsifiers and trypsin (TR) as biomolecules were examined on Fe3O4/PS/P(DM-EGDM) composite polymer particles at different temperatures. The native conformation of TR was followed by measuring the specific activity under various adsorption conditions. The activity of the adsorbed TR on composite polymer particles was higher than those of the free TR and TR adsorbed on Fe3O4/PS particles.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Y. Noriko, N. Hiromichi, A. Hideki, and S. Tatsuo,J. Appl. Polym. Sci.,50, 765 (1993).

    Article  Google Scholar 

  2. X. H. Li and Z. H. Sun,J. Appl. Polym. Sci.,58, 1991 (1995).

    Article  CAS  Google Scholar 

  3. D. Horák, L. Bohácek, and M. Šubrt,J. Polym. Sci. Part A: Polym. Chem.,38, 1161 (2000).

    Article  Google Scholar 

  4. T. M. Cocker, C. J. Fee, and R. A. Evans,Biotechnol. Bioeng.,53, 79 (1997).

    Article  CAS  Google Scholar 

  5. Y. Lee, J. Rho, and B. Jung,J. Appl. Polym. Sci.,89, 2058 (2003).

    Article  CAS  Google Scholar 

  6. C. Yang, H. Liu, Y. Guan, J. Xing, J. Liu, and G. Shan,J. Magn. Magn. Mater.,293, 187 (2005).

    Article  CAS  Google Scholar 

  7. J. Lee and M. Senna,Colloid Polym. Sci.,273, 76 (1995).

    Article  CAS  Google Scholar 

  8. J. Ugelstad, T. Ellingsen, and A. Berge,et al., PCT Int. Appl. WO Patent 8, 303, 0920 (1983).

    Google Scholar 

  9. T. K. Nakamae, M. Okubo, M. Sue, M. Shimao, and M. Komura,Kobunshi Ronbunshu,31, 669 (1974).

    Article  Google Scholar 

  10. M. Okubo and H. Ahmad,J. Polym. Sci. Part A: Polym. Chem.,34, 3147 (1996).

    Article  CAS  Google Scholar 

  11. M. Okubo and H. Ahmad,Colloid Polym. Sci.,274, 112 (1996).

    Article  CAS  Google Scholar 

  12. M. Okubo and H. Ahmad,Colloid Surface A,153, 429 (1999).

    Article  CAS  Google Scholar 

  13. H. Ahmad, M. Okubo, Y. O. Kamatari, and H. Minami,Colloid Polym. Sci.,280, 310 (2002).

    Article  CAS  Google Scholar 

  14. M. A. Alam, M. A. J. Miah, and H. Ahmad,J. Polym. Mater.,20, 243 (2003).

    CAS  Google Scholar 

  15. M. A. Alam, M. A. J. Miah, and H. Ahmad,J. Polym. Mater.,24, 85 (2007).

    CAS  Google Scholar 

  16. A. S. Hoffman,J. Control. Release,6, 297 (1987).

    Article  CAS  Google Scholar 

  17. B. Jeong, Y. H. Bae, D. S. Lee, and S. W. Kim,Nature,388, 860 (1997).

    Article  CAS  Google Scholar 

  18. Y. Deng and R. Pelton,Macromolecules,28, 4617 (1995).

    Article  CAS  Google Scholar 

  19. H. Kawaguchi and K. Fujimoto,Bioseparation,6, 879 (1997).

    Google Scholar 

  20. T. Miyata, N. Asami, and T. Uragami,Macromolecules,32, 2082 (1999).

    Article  CAS  Google Scholar 

  21. A. M. Schmidt,Colloid Polym. Sci.,285, 953 (2007).

    Article  CAS  Google Scholar 

  22. F. Sauzedde, A. ElaÏssari, and C. Pichot,Colloid Polym. Sci.,277, 1041 (1999).

    Article  CAS  Google Scholar 

  23. J. Cai, J. Guo, M. Ji, W. Yang, C. Wang, and S. Fu,Colloid Polym. Sci.,285, 1607 (2007).

    Article  CAS  Google Scholar 

  24. Y. Zhu and Q. Wu,J. Nanopart. Res.,1, 393 (1999).

    Article  CAS  Google Scholar 

  25. B. Z. Tang, Y. Geng, J. W. Y. Lam, B. Li, X. Jing, X. Wang, A. B. Pakhomov, and X. X. Zhang,Chem. Mater.,11, 1581 (1999).

    Article  CAS  Google Scholar 

  26. H. Ahmad, M. S. Rahman, M. A. J. Miah, and A. M. I. Ali,Colloid Polym. Sci.,279, 1039 (2001).

    Article  CAS  Google Scholar 

  27. J. L. Zhang, R. S. Srivastava, and R. D. K. Misra,Langmuir,23, 6342 (2007).

    Article  CAS  Google Scholar 

  28. M. Ma, Y. Zhang, W. Yu, H. Y. Shen, H. Q. Zhang, and N. Gu,Colloid Surface A,212, 219 (2003).

    Article  CAS  Google Scholar 

  29. F. Sayar, G. Güven, and E. Pişkin,Colloid Polym. Sci.,284, 965 (2006).

    Article  CAS  Google Scholar 

  30. M. Okubo and H. Ahmad,Colloid Polym. Sci.,273, 817 (1995).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Chemistry, Rajshahi University, 6205, Rajshahi, Bangladesh

    Hasan Ahmad, M. Abdur Rahman & M. A. Jalil Miah

  2. MPI of Colloid and Interface, Am Mühlenberg, D 14476, Golm, Germany

    Klaus Tauer

Authors
  1. Hasan Ahmad
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. Abdur Rahman
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M. A. Jalil Miah
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Klaus Tauer
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Hasan Ahmad or Klaus Tauer.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ahmad, H., Rahman, M.A., Jalil Miah, M.A. et al. Magnetic and temperature-sensitive composite polymer particles and adsorption behavior of emulsifiers and trypsin. Macromol. Res. 16, 637–643 (2008). https://doi.org/10.1007/BF03218573

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF03218573

Keywords

Search

Navigation