Skip to main content
Log in

Increased FDG uptake in the wall of the right atrium in people who participated in a cancer screening program with whole-body PET

  • Short Communication
  • Published:
Annals of Nuclear Medicine Aims and scope Submit manuscript

Abstract

The purpose of this study was to evaluate the characteristics of patients who showed increased FDG uptake in the wall of the right atrium.

We have encountered 10 patients with increased activity in the wall of the right atrium among a total of 2,367 examinees who participated in our cancer screening program with whole-body PET. The mean age of these examinees was 62.9 yr, higher than that of the total population. All suffered from cardiac disorders, especially atrial fibrillation. FDG accumulated almost exclusively in the wall of the right atrium, whereas only slight activity was seen in the wall of the left atrium. Although the average size of the right atria was significantly enlarged, left atria were more severely dilated than right ones. Therefore overload does not seem to account for the FDG accumulation in the wall of the right atrium.

In conclusion, the increased activity in the wall of the right atrium was a rare finding that was made in older people who suffered from cardiac disease. Although the mechanism of induction of the high metabolic state of glucose in the wall of the right atrium remains unclear, this unusual activity would be another false positive finding in cancer screening with whole-body FDG PET.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Opie LH. The Heart: physiology, from cell to circulation. 3rd ed. Philadelphia, Lippincott-Raven, pp. 295–342, 1998.

    Google Scholar 

  2. Yasuda S, Ide M, Takagi S, Shohtsu A. Cancer screening with whole-body FDG PET.KAKU IGAKU (Jpn J Nucl Med) 33: 1065–1071, 1996.

    CAS  Google Scholar 

  3. Fujii H, Yasuda S, Ide M, Takahashi W, Shohtsu A, Kubo A. Increased fluorine-18 fluorodeoxyglucose uptake in the right atrial wall in a patient with atrial fibrillation.Clin Nucl Med 24, 1999 (in the press).

  4. Tamaki N, Yonekura Y, Konishi J. Myocardial FDG PET studies with the fasting, oral glucose-loading or insulin clamp methods.J Nucl Med 33: 1263–1268, 1992.

    PubMed  CAS  Google Scholar 

  5. Yasuda S, Ide M, Takagi S, Shohtsu A, Mitomi T, Kobayashi S, et al. Cancer screening with whole-body FDG PET images without attenuation correction.KAKU IGAKU (Jpn J Nucl Med) 33: 367–373, 1996.

    CAS  Google Scholar 

  6. White CW, Kerber RE, Weiss HR, Marcus ML. The effects of atrial fibrillation on atrial pressure-volume and flow relationships.Circ Res 51: 205–215, 1982.

    PubMed  CAS  Google Scholar 

  7. McHale PA, Rembert JC, Greenfield JC. Effect of atrial fibrillation on atrial blood flow in conscious dogs.Am J Cardiol 51: 1722–1727, 1983.

    Article  PubMed  CAS  Google Scholar 

  8. Liu CK, Greenspan G, Piccirillo. Atrial infarction of the heart. Circulation 23: 331–338, 1961.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Hirofumi Fujii.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Fujii, H., Ide, M., Yasuda, S. et al. Increased FDG uptake in the wall of the right atrium in people who participated in a cancer screening program with whole-body PET. Ann Nucl Med 13, 55–59 (1999). https://doi.org/10.1007/BF03165430

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF03165430

Key words

Navigation