Abstract
The inhibitors present in the extracts ofCinchoma ledgeriana, Emblica officinalis, Chrysobalanus C. icaco andTerminalia chebula were heat-stable, resistant to autoclaving, aging and desiccation for a week. However, they did not withstand dialysis for 48 hrs (exceptT. chebula extract.) These four extracts markedly inhibited the virus even on dilution in the ratio of 1⤜1 but viral infectivity was sharply reduced at higher dilutions in each case. Moreover, the inhibitors in the stem bark extract ofC. ledgeriana, fruit pericarp extract ofE. officinalis andT. chebula were highly inhibitory even at pH 10·0, whereas inhibition of the virus by leaf extract ofC. icaco was reduced to 24 per cent only at the same pH. The inhibitors in these four extracts were found to be probably not proteinaceous in nature, when precipitated with ammonium sulphate and ethanol.
Abstract
V eextraktech zCinchonaledgeriana, Emblica officinalis, Chrysobalanus icaco a Terminalia chebula byly nalezeny termostabilní inhibitory, odolné vůči autoklávování a stálé i při vysýchání po dobu jednoho týdne. Tyto čtyři extrakty inhibovaly viry i při zředění 1⤜1 a virová infektivita byla výrazně snížena při vyšším zředění. Inhibitory z kůry kmene uC. ledgeriana a z perikarpu plodů uE. officinalis aT. chebula byly značně inhibiění i při pH 10,00 zatímco virální infektivita listových extraktů uC. icaco byla redukována při tomto pH na 24%. Předpokládáse, že inhibitory jež je možeo srážet síranem amonným a ethanolem nejsou bílkovinné povahy.
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A part of the Ph. D. thesis submitted by the senior author to the Aligarh Muslim University, Aligarh, India.
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Verma, V.S., Raychaudhuri, S.P. & Khan, A.M. Properties and nature of inhibitors of potato virus X in four medicinal plant extracts. Biol Plant 11, 384–387 (1969). https://doi.org/10.1007/BF02921405
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DOI: https://doi.org/10.1007/BF02921405