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Changes in serum lipids in normal and diabetic guinea pigs on feeding Phaseolus aureus (Green gram)

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Abstract

Normal and alloxan induced diabetic guinea pigs were kept on whole seed diet of green gram for 4 weeks. Serum total lipids were found to be significantly decreased in both normal and diabetic guinea pigs (P <0.001)—Both free and esterified fractions of cholesterol were found to be lowered significantly in diabetic animals (P<0.05; <0.01, respectively), whereas only esterified fraction was reduced significantly in case of normals (P<0.05). Significant lowering of triglyceride levels (P<0.01) was also noticed in both normal as well as diabetic guinea pigs while phospholipids remained almost unaffected. Green gram feeding decreased the total cholesterol / phospholipid ratio from 0.630 to 0.625 in normal and from 1.039 to 0.850 in diabetic guinea pigs indicating its antiatherogenic nature.

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Srivastava, A., Joshi, L.D. & Singh, S.P. Changes in serum lipids in normal and diabetic guinea pigs on feeding Phaseolus aureus (Green gram). Indian J Clin Biochem 4, 50–57 (1989). https://doi.org/10.1007/BF02867652

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  • DOI: https://doi.org/10.1007/BF02867652

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