Summary
A community oriented intervention program was initiated in 1985 in 12 rural communities in southern Israel to identify and treat women of reproductive age with markers of Chlamydia trachomatis (CT) infection. Among 860 women tested, 21 (2.4%) had CT IgG antibody titers ≥128, or CT IgA antibody titers ≥16, and 9 of these women had positive cultures for CT. The 21 women, as well as their male partners, received specific anti-CT treatment, and were followed up for 5 years to assess obstetric complications, and to evaluate the effectiveness of treatment. In 9 women positive cultures became negative. In 13 out of the 17 cases with sequential follow-up a four fold decrease in IgG specific antibody titers was observed. Yet, in all but two of the cases, IgA specific antibody titers remained ≥16.
Similar content being viewed by others
References
Gravett MG, Nelson HP, DeRouan T, et al. (1986) Independent association of bacterial vaginosis and Chlamydia trachomatis infection with adverse pregnancy outcome. JAMA 256:1899–1903
Gump DW, Gibson M, Ashikaga T (1983) Evidence of prior pelvic inflammatory disease and its relationship to Chlamydia trachomatis antibody and intrauterine contraceptive device use in infertile women. Am J Obstet Gynecol 146:153–159
Martin DH, Koutsky L, Eschenbach DA, et al. (1982) Prematurity and perinatal mortality in pregnancies complicated by antepartum maternal Chlamydia trachomatis infections. JAMA 247:1585–1590
McGregor JA (1989) Chlamydial infection in women. Obstet Gynecol Clin NA 16:565–592
Phillips RS, Aronson MD, Taylor WC, et al. (1987) Should tests for Chlamydia trachomatis cervical infection be done during routine gynecologic visits: an analysis of alternative strategies. Ann Intern Med 17:188–194
Ripa KT, Mardh PA (1970) Cultivation of Chlamydia trachomatis in cycloheximide-treated McCoy cells. J Clin Microbiol 6:328–331
Sarov I, Kleinman D, Holcberg G, et al. (1986) Specific IgG and IgA antibodies to Chlamydia trachomatis in infertile women. Int J Fertil 31:193–197
Thelin I, Wennstrom AM, Mardh PA (1980) Contact tracing in patients with genital chlamydial infection. Br J Vener Dis 56:259–262
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Chaim, W., Edelstein, Z., Sarov, B. et al. The long term follow-up of asymptomatic women with Chlamydia trachomatis. Arch Gynecol Obstet 251, 159–164 (1992). https://doi.org/10.1007/BF02718380
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02718380