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Aminoglycoside-modifying enzymes in clinical isolates ofAcinetobacter calcoaceticus

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Abstract

Aminoglycoside-modifying enzymes were identified in clinical strains ofAcinetobacter calcoaceticus subsp.anitratus (Herellea vaginicola) isolated between 1971 and 1979. Resistance to kanamycin, neomycin, and lividomycin was explained by an aminoglycoside-3′-phosphotransferase enzyme. The resistance of gentamicin was due to an aminoglycoside 3N-acetyltransferase type I enzyme which had not previously been described in this species. Several strains producing both enzymes showed resistance to kanamycin, gentamicin, lividomycin, neomycin, and sisomicin and susceptibility to tobramycin and amikacin.

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Authors and Affiliations

  1. Department of Microbiology, Bichat Hospital, 46 Rue Huchard, F-75877, Paris Cedex 18, France

    E. Bergogne-Berézin & M. L. Joly

  2. C.N.R.S., C.E.R.C.O.A., 2 Rue Henry Dunant, F-94320, Thiais, France

    N. Moreau & F. Le Goffic

Authors
  1. E. Bergogne-Berézin
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  2. M. L. Joly
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  3. N. Moreau
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  4. F. Le Goffic
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Bergogne-Berézin, E., Joly, M.L., Moreau, N. et al. Aminoglycoside-modifying enzymes in clinical isolates ofAcinetobacter calcoaceticus . Current Microbiology 4, 361–364 (1980). https://doi.org/10.1007/BF02605378

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