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Antigen-antibody interaction at specific binding sites: A mechanism involving iminazole

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Résumé

L'auteur propose un mode de liaison entre les molécules d'antigène et d'anticorps au moyen d'un centre réactif spécifique résultant de l'interaction d'un groupe récepteur carboxylique de l'antig`ene avec le groupe iminazole d'une unite particuli`ere histidine de l'anticorps. Plusieurs faits viennent done confirmer l'hypoth`ese selon laquelle nous suggérons une analogie entre les interactions antig`eneanticorps et les interactions de certains enzymes et de leurs substrats.

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Authors and Affiliations

  1. Microbiological Research Establishment, Porton, Wilts, and The University, Edgbaston, Birmingham

    J. H. Turnbull

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  1. J. H. Turnbull
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Turnbull, J.H. Antigen-antibody interaction at specific binding sites: A mechanism involving iminazole. Experientia 15, 304–305 (1959). https://doi.org/10.1007/BF02158536

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