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Normative data for two neuropsychological tests sensitive to frontal dysfunction

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Abstract

Interest in frontal functions has progressively increased over recent years; however, despite this, there are only a few “frontal” tasks for which Italian normative data are available. The objective of this study was to obtain reference values for two frontal tests from a random sample of normal adults: the first (the Test of Classification and Recall of Pictures) has been shown to reveal selective impairment in patients with unilateral frontal excision; the second (the Odd-Man-Out Test) derives from tasks which have been used to evaluate frontal functions in animals and detect frontal impairment in Parkinson patients. We tested 100 normal subjects, aged 22 to 79 years, stratified by education according to the Italian school system. The correction grids for both tests are also presented. The usefulness of these tests is represented not only by their sensitivity to frontal impairment, but also by the possibility of dissociating the various cognitive aspects of frontal lobe dysfunction.

Sommario

L'interesse nei confronti delle funzioni frontali è progressivamente aumentato negli ultimi anni. Nonostante ciò, solo per pochi test “frontali” sono disponibili dati normativi italiani. Lo scopo di questo studio era ottenere valori normativi per due test “frontali” utilizzando un campione di soggetti normali selezionati in maniera casuale. Il primo test, ossia il Test di Classificazione e Rievocazione di Figure, risulta selettivamente compromesso in pazienti sottoposti a escissione frontale unilaterale; il secondo test, ossia il Test della Percora Nera, deriva da compiti utilizzati per rilevare la compromissione frontale negli animali ed è stato usato per individuare una disfunzione di tipo frontale nei parkinsoniani. Sono stati testati 100 soggetti normali, di età compresa fra i 22 e i 79 anni, stratificati per scolarità secondo il modello scolastico italiano. Vengono presentate le griglie di correzione per entrambi i test. La loro utilità consiste non solo nella loro sensibilità al danno frontale, ma anche nella possibilità di dissociare aspetti cognitivi differenti della disfunzione dei lobi frontali.

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References

  1. Alexander G.E., De Long M.R., Strick P.L.:Parallel organisation of functionally segregated circuits linking basal ganglia and cortex. Ann. Rev. Neurosci. 9: 357–381, 1986.

    PubMed  Google Scholar 

  2. Arnett P.A., Rao S.M., Bernardin L. et al.:Relationship between frontal lobe lesions and Wisconsin Card Sorting Test performance in patients with multiple sclerosis. Neurology 44: 420–425, 1994.

    PubMed  Google Scholar 

  3. Baddeley A.:Working Memory. London: Oxford, University Press, 1986.

    Google Scholar 

  4. Brown M.G., Marsden C.D.:“Subcortical dementia”: the neuropsychological evidence. Neuroscience 25: 363–387, 1988.

    PubMed  Google Scholar 

  5. Capitani E., Laiacona M.:Aging and psychometric diagnosis of intellective impairment: some considerations on test scores and their use. Developmental Neuropsychology 4: 325–330, 1988.

    Google Scholar 

  6. Cicerone K.D., Lazar R.M., Shapiro W.R.,Effects of frontal lobe lesions on hypothesis sampling during concept formation. Neuropsychologia 21: 513–524, 1983.

    PubMed  Google Scholar 

  7. Downes J.J., Sharp H.M., Costall B.M. et al.:Alternating fluency in Parkinson's disease. An evaluation of the attentional theory of cognitive impairment. Brain 116: 887–902, 1993.

    PubMed  Google Scholar 

  8. Farina E., Cappa S.F., Polimeni M. et al.:Frontal type dysfunction in the early stages of Parkinson's disease. Acta Neurol. Scand. 90: 34–38, 1994.

    PubMed  Google Scholar 

  9. Flowers K.A., Robertson C.:The effect of Parkinson's disease on the ability to maintain a mental set. J. Neurol. Neurosurg. Psychiatry 48: 517–529, 1985.

    PubMed  Google Scholar 

  10. Folstein M.F., Folstein S.E., McHugh P.R.:“Mini Mental State”. A practical method for grading the mental state of patients for the clinician. J. Psych. Res. 12: 189–198, 1975.

    Google Scholar 

  11. Fritsch G., Hitzig E.:On the electrical excitability of the cerebrum. In: Pribram K.H. (Ed.). Brain and behavior 2. Perception and action. Baltimore, Penguin Books, 1969.

    Google Scholar 

  12. Gustafson L., Brun A., Passant U.:Frontal lobe degeneration of non-Alzheimer type. In: Rossor M.N. (Ed.), Unusual dementias- Baillière's Clinical Neurology. Vol. 1, No. 3, 559–582, 1992.

    Google Scholar 

  13. Incisa Della Rocchetta A.:Classification and recall of pictures after unilateral frontal or temporal lobectomy. Cortex 22: 189–211, 1986.

    PubMed  Google Scholar 

  14. Lees A.J., Smith E.:Cognitive deficits in the early stages of Parkinson's disease. Brain 106: 257–270, 1983.

    PubMed  Google Scholar 

  15. Levin H.S., Einsenberg H.M., Benton A.L.:Frontal lobe function and dysfunction. New York, Oxford University Press, 1991.

    Google Scholar 

  16. Lezak M.D.:Neuropsychological assessment. Oxford University Press. New York, Oxford, 1983.

    Google Scholar 

  17. Milner B.:Effect of different brain lesions on card sorting test. The role of the frontal lobe. Arch. Neurol. 9: 90–101, 1963.

    Google Scholar 

  18. Neary D., Snowden J.S., Northen B., Gouldin P.:Dementia of frontal lobe type. J. Neurol. Neurosurg. Psychiatry 51: 353–361, 1988.

    PubMed  Google Scholar 

  19. Novelli G., Papagno C., Capitani E. et al.:Tre test clinici di memoria verbale a lungo termine. Taratura su soggetti normali. Arch. Neurol. Psich. Psicol. 47: 278–296, 1986.

    Google Scholar 

  20. Novelli G., Papagno C., Capitani E. et al.:Tre test clinici di ricerca e produzione lessicale. Taratura su soggetti normali. Arch. Neurol. Psich. Psicol. 47: 477–506, 1986.

    Google Scholar 

  21. Owen A.M., Roberts A.C., Hodges J.R. et al.:Contrasting mechanisms of impaired attentional set-shifting in patients with frontal lobe damage or Parkinson's disease. Cortex 116: 1159–1175, 1993.

    Google Scholar 

  22. Settlage P., Zable M., Harlow H.F.,Problem solution by monkeys following bilateral removal of the prefrontal areas. VI: Performance on tests requiring contradictions in reactions to similar and identical stimuli. J. Exp. Psychol. 38: 50–65, 1948.

    Google Scholar 

  23. Spinnler H.:Il decadimento demenziale. Il Pensiero Scientifico Editore, Roma, 1985.

    Google Scholar 

  24. Spinnler H., Tognoi G. (eds.):Standardizzazione e taratura italiana di test neuropsicologici. Ital. J. Neurol. Sci. 6 (suppl. 8), 1987.

  25. Taylor A.E., Saint-Cyr J.A., Lang A.E.,Frontal lobe dysfunction in Parkinson's disease. The cortical focus of neostriatal outflow. Brain 109: 845–883, 1986.

    PubMed  Google Scholar 

  26. Van der Berchen J.H.L., Cools A.R.,Evidence for a role of the caudate nucleus in the sequential organisation of behaviour. Behav. Brain Res. 4: 319–337, 1982.

    PubMed  Google Scholar 

  27. Vikki J.:Deficient programming in spatial learning after frontal lobe damage. Neuropsychologia 27: 971–976, 1989.

    PubMed  Google Scholar 

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Pomati, S., Farina, E., Magni, E. et al. Normative data for two neuropsychological tests sensitive to frontal dysfunction. Ital J Neuro Sci 17, 201–209 (1996). https://doi.org/10.1007/BF01995684

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