Skip to main content
SpringerLink
Log in

Analysis of creams

III. Application of gas-liquid chromatography. Part I

  • Original Articles
  • Published:
Pharmaceutisch Weekblad Aims and scope Submit manuscript

Abstract

The possibilities of the gas-liquid chromatographic analysis with flame ionization detection of creams of the o/w emulsion type were investigated. Interferences by cream base components in the determination of the active compounds were studied. It appeared to be possible to determine active compounds with a retention index lower than 1900 onov-17 (e.g. methyl salicylate, menthol, thymol, camphor) without clean-up of the cream samples; for the determination of compounds with retention indices between 1900 and 3700, a simple clean-up step suffices.

The possible analysis of some of the cream base components together with the active compounds of the creams was investigated as well. Cetomacrogol emulsifying wax, lanette wax sx and cetiol v could be determined easily, whether or not a sample clean-up step was incorporated.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Choi, P., W.J. Criddle andJ. Thomas (1979)Analyst 104, 451–455.

    Google Scholar 

  • Houwen, O.A.G.J.Van Der (1980) Unpublished results.

  • Sane, R.T., P.D. Karkanis andP.G. Anaokar (1980)Ind. J. Pharm. Sci. 41, 143–144.

    Google Scholar 

  • Sapio, J.P., K. Sethachutkul andJ.E. Moody (1979)J. Pharm. Sci. 68, 506–508.

    PubMed  Google Scholar 

  • Vaart, F.J. Van De, A. Hulshoff andA.W.M. Indemans (1980a)Pharm. Weekbl. 115, 1429–1438;Ibidem (1980b)Pharm. Weekbl. Sci. Ed. 2, 179–185;Ibidem (1982)Pharm. Weekbl: Sci. Ed. 4, 16–20.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Pharmaceutical Laboratory, Department of Analytical Pharmacy, University of Utrecht, Catharijnesingel 60, 3511, GH Utrecht, The Netherlands

    O. A. Lake, A. Hulshoff & A. W. M. Indemans

Authors
  1. O. A. Lake
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. Hulshoff
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. W. M. Indemans
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lake, O.A., Hulshoff, A. & Indemans, A.W.M. Analysis of creams. Pharmaceutisch Weekblad Scientific Edition 4, 43–48 (1982). https://doi.org/10.1007/BF01963660

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01963660

Keywords

Search

Navigation