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Anti-endotoxin (anti-lipid-A) antibodies

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Summary

Anti-lipid-A, anti-endotoxin, antibodies have been measured by a passive haemolysis test using antigen from anE. coli Re mutant. Titres in the normal population are low but do rise in situations in which there has been gram-negative sepsis. Absence of raised titres in other situations has profound implications.

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Author information

Authors and Affiliations

  1. Department of Medicine, Royal Victoria Infirmary, NE1 4LP, Newcastle upon Tyne, England

    D. Blake, A. N. Hamlyn, S. Proctor & E. N. Wardle

Authors
  1. D. Blake
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  2. A. N. Hamlyn
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  3. S. Proctor
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  4. E. N. Wardle
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Additional information

We are most grateful to Dr Günter Schmidt of Freiburg for his gift of Lipid-A antigen. We also thank Dr L. Monnens of Nijmegen and Dr T.M. Barratt of London for their sera.

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Blake, D., Hamlyn, A.N., Proctor, S. et al. Anti-endotoxin (anti-lipid-A) antibodies. Experientia 36, 254–255 (1980). https://doi.org/10.1007/BF01953765

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