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Electron microscopic study of the formation of African horse-sickness virus

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Summary

BHK 21/13 cells infected with African horse-sickness virus (strain 13/63, type 3) for varying periods of time have been studied with the electron microscope. Evidence is presented to show that the virus does not multiply in the nucleus, but that replication occurs in the cytoplasmic matrix. It is also indicated that the particle often leaves the host cell with an envelope derived from the cell membrane. The diameter of the particle is roughly estimated to be 70 mμ., excluding the “envelope”.

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Author notes

  1. G. Lecatsas

    Present address: Sections of Molecular Biology and Virology, Veterinary Research Institute, P.O. Onderstepoort, Republic of South Africa

Authors and Affiliations

  1. Sections of Molecular Biology and Virology, Veterinary Research Institute, P.O. Onderstepoort, Republic of South Africa

    B. J. Erasmus

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  1. G. Lecatsas
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  2. B. J. Erasmus
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Lecatsas, G., Erasmus, B.J. Electron microscopic study of the formation of African horse-sickness virus. Archiv f Virusforschung 22, 442–450 (1967). https://doi.org/10.1007/BF01242965

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  • DOI: https://doi.org/10.1007/BF01242965

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