Skip to main content
Log in

The use and abuse of models

  • Perspectives in Pharmacokinetics
  • Published:
Journal of Pharmacokinetics and Biopharmaceutics Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. J. S. Beck and A. Rescigno. Calcium kinetics: the philosophy and practice of science.Phys. Med. Biol. 15:566–567 (1970).

    Article  CAS  PubMed  Google Scholar 

  2. K. R. Popper.Logik der Forschung. Vienna, 1935, passim.

  3. K. Zierler. A critique of compartmental analysis.Ann. Rev. Biophys. Bioeng. 10:531–562 (1981).

    Article  CAS  Google Scholar 

  4. A. Rescigno and I. W. Richardson. The deterministic theory of population dynamics.In R. Rosen (ed.),Foundations of Mathematical Biology, Vol. 3, Academic Press, New York, 1973, pp. 283–360.

    Chapter  Google Scholar 

  5. H. Becquerel. Sur les radiations émises par phosphorescence.Compt. Rend. 122:420–421 (1896).

    CAS  Google Scholar 

  6. H. Becquerel. Sur les radiations invisibles émises par les corps phosphorescents.Compt. Rend. 122:501–503 (1896).

    Google Scholar 

  7. T. Teorell. Kinetics of distribution of substances administered to the body.Arch. Int. Pharmacodyn. Thér. 57: 205–240 (1937).

    CAS  Google Scholar 

  8. A. Rescigno. On transfer times in tracer experiments.J. Theoret. Biol. 39:9–27 (1973).

    Article  CAS  Google Scholar 

  9. P.-E. E. Bergner. The significance of certain tracer kinetical methods, especially with respect to the tracer dynamic definition of metabolic turnover.Acta Radiol. Suppl. 210:15 (1962).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Supported in part by a grant from “Consiglio Nazionale delle Richerche”, Rome, Italy.

SeeJ. Pharmacokin. Biopharm. 15:341–344.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Rescigno, A., Beck, J.S. & Thakur, A.K. The use and abuse of models. Journal of Pharmacokinetics and Biopharmaceutics 15, 327–340 (1987). https://doi.org/10.1007/BF01066325

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01066325

Keywords

Navigation