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Bioaccumulation, metabolism, and effects of DDT, fenitrothion, and chlorpyrifos onSaccharomyces cerevisiae

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Abstract

Saccharomyces cerevisiae accumulated DDT, fenitrothion, and chlorpyrifos rapidly from yeast glucose medium. The maximum concentrations of DDT, fenitrothion, and chlorpyrifos accumulated were 8,253, 18,960 and 11,579 μg/g (dry wt), respectively. The pattern of accumulation was similar for all insecticides. The bioconcentration factor was inversely proportional to insecticide solubilities.Saccharomyces metabolized the three insecticides, but only two metabolites of DDT (DDD and DDE) were identified. Protoplast cultures were more sensitive to DDT and fenitrothion compared to normal cultures but were less sensitive to chlorpyrifos. Both the normal and protoplast cultures recovered from the toxic effect after 24 hr.

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References

  • Ahmed MK, Casida JE (1958) Metabolism of some organophosphorus insecticides by microorganisms. J Econ Entomol 51:59–63

    Google Scholar 

  • Anderson JP, Lichtenstein EP, Whittingham WF (1970) Effect ofMucor alternans on the persistence of DDT and dieldrin in culture and in soil. J Econ Entomol 63:1595–1599

    PubMed  Google Scholar 

  • Barry AL (1968) The accumulation of14C-DDT by aquatic fungi. MSc thesis, University Salford, Lancashire, England

    Google Scholar 

  • Boush GM, Batterton JC (1972) Ecological aspects of pesticide microbial relationship. In: Matsumura F, Boush GM, Misato T (eds) Environmental toxicology of pesticides. Academic Press, London, pp 401–422

    Google Scholar 

  • Fishbein L (1976) Teratogenic, mutagenic, and carcinogenic effects of insecticides. In: Wilkison CF (ed) Insecticide biochemistry and physiology, Plenum Press, New York p 555

    Google Scholar 

  • Fries GR, Marrow GS, Gordon CH (1969) Metabolism ofo,p′- andp,p′-DDT by rumen microorganisms. J Agric Food Chem 17:860–862

    Google Scholar 

  • Juengst FW, Alexander M (1976) Conversion of 1,1,1-trichioro-2,2-bis (p-chlorophenyl) ethane (DDT) to water-soluble products by microorganisms. J Agric Food Chem 24:111–115

    PubMed  Google Scholar 

  • Lal R (1982) Accumulation, metabolism, and effects of organophosphorus insecticides on microorganisms: Advances Appl Microbiol 28:149–200

    Google Scholar 

  • Lal R, Saxena DM (1982) Accumulation, metabolism, and effects of organochlorine insecticides on microorganisms. Microbiol Rev 46:95–127

    PubMed  Google Scholar 

  • Lal R and Lal S (eds) (1987) Pesticides and nitrogen cycle, CRC Press, Boca Raton, Florida (in press)

    Google Scholar 

  • Miyazaki S, Thorsteinson AJ (1972) Metabolism of DDT by freshwater diatoms. Bull Environ Contam Toxicol 8:81–83

    PubMed  Google Scholar 

  • Paris DF, Lewis DL, Barnell JT, Boughman GL (1975) Microbial degradation and accumulation of pesticides in aquatic system. US Environmental Protection Agency, 660/3-75-007, Athens, GA

  • Rice CP, Sikka HC (1973) Uptake and metabolism of DDT by six species of marine algae. J Agric Food Chem 21:148–152

    PubMed  Google Scholar 

Download references

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Lal, S., Lal, R. Bioaccumulation, metabolism, and effects of DDT, fenitrothion, and chlorpyrifos onSaccharomyces cerevisiae . Arch. Environ. Contam. Toxicol. 16, 753–757 (1987). https://doi.org/10.1007/BF01055426

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  • DOI: https://doi.org/10.1007/BF01055426

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