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Chemiosmotic concept of the membrane bioenergetics: What is already clear and what is still waiting for elucidation?

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Abstract

The present state of the chemiosmotic concept is reviewed. Special attention is paid to (i) further progress in studies on the Na+-coupled energetics and (ii) paradoxical bioenergetic effects when protonic or sodium potentials are utilized outside the coupling membrane (TonB-mediated uphill transports across the outer bacterial membrane). A hypothesis is put forward assuming that the same principle is employed in the bacterial flagellar motor.

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Skulachev, V.P. Chemiosmotic concept of the membrane bioenergetics: What is already clear and what is still waiting for elucidation?. J Bioenerg Biomembr 26, 589–598 (1994). https://doi.org/10.1007/BF00831533

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