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Mechanisms of oral sensation

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Abstract

Sensory nerves that supply mechanoreceptors in the mucosal lining of the oral cavity, pharynx, and larynx provide the substrate for a variety of sensations. They are essential for the perception of complex or composite sensory experiences including oral kinesthesia and oral stereognosis. Relevant to the concerns of the oral health care delivery specialist they also contribute to initiation of reflexes and coordination and timing of patterned motor behaviors. The response of oral mechanoreceptors to natural stimuli is determined to a large degree by morphological factors such as the nature of the relationship between nerve ending and certain cellular specializations, their distribution in the mucosa, the diameter of their primary afferent nerve fibers, and the central distribution of these fibers in the brainstem. Because of morphological similarities to certain cutaneous mechanoreceptors, the mucosal lining may be considered as an internal continuation of the large “receptor sheet” for localization and detection of mechanical stimuli. In some regions of the oral, pharyngeal, and laryngeal mucosa, this analogy is appropriate whereas in others, existing data suggest a different role consistent with regionally specific demands (i.e., initiation of protective reflexes).

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References

  1. Munger BL: The general somatic afferent terminals in oral mucosae. In: Simon SA, Roper SD (eds.). Mechanisms of Taste Transduction. Boca Raton, FL: CRC Press, 1993, pp 83–101

    Google Scholar 

  2. Munger BL: The cytology and ultrastructure of sensory receptors in the adult and newborn primate tongue. In: Bosma JF (ed.): Fourth Symposium on Oral Sensation and Perception: Development of the Fetus and Infant. Bethesda, MD: DHEW, National Institutes of Health, 1973, pp 75–93

    Google Scholar 

  3. Grossman RC, Hattis BF, Ringel RL: Oral tactile experience. Archs Oral Biol 10:691–705, 1965

    Google Scholar 

  4. Seto H: Studies on the Sensory Innervation (Human Sensibility), 2nd ed. Igaku Shoin Ltd. Springfield: CC Thomas, 1963

    Google Scholar 

  5. Dubner R, Sessle BJ, Storey AT: Neural Basis of Oral and Facial Function. New York, NY: Plenum Press, 1978

    Google Scholar 

  6. Ross MH, Reith ET, Romrell LJ: Histology: A Text and Atlas, 2nd ed. Baltimore, MD: Williams and Wilkins, 1989

    Google Scholar 

  7. Henkin RI, Banks V: Tactile perception on the tongue, palate and the hand of normal man. In: Bosma JF (ed.). Symposium on Oral Sensation and Perception. Springfield, IL: CT Thomas, 1967, pp 182–187

    Google Scholar 

  8. Ringel RL, Ewanowski SJ: Oral perception: I. Two-point discrimination. J Hearing Speech Res 8:389–397, 1965

    Google Scholar 

  9. Ringel RL: Oral region two-point discrimination in normal and myopathic subjects. In: Bosma JF (ed.): Second Symposium on Oral Sensation and Perception. Springfield, IL: CT Thomas, 1970, pp 309–322

    Google Scholar 

  10. Byers MR: Sensory innervation of periodontal ligament of rat molars consists of unencapsulated Ruffini-like mechanoreceptors and free nerve endings. J Comp Neurol 231:500–518, 1985

    Google Scholar 

  11. Byers MR: Dental sensory receptors. Int Rev Neurobiol 25:39–93, 1984

    Google Scholar 

  12. Byers MR, Dong WK: Comparison of trigeminal receptor location and structure in the periodontal ligament of different types of teeth from the rat, cat, and monkey. J Comp Neurol 279:117–127, 1989

    Google Scholar 

  13. Capra NF, Dessem D: Central distribution of trigeminal primary afferent neurons: topographical and functional considerations. CRC Rev Oral Biol Med 4:1–52, 1992

    Google Scholar 

  14. Storey AT: A functional analysis of sensory units innervating epiglottis and larynx. Exp Neurol 20:366–383, 1968

    Google Scholar 

  15. Storey AT: Laryngeal initiation of swallowing. Exp Neurol 20:359–365, 1968

    Google Scholar 

  16. Marfurt CF: The central projections of trigeminal primary afferent neurons in the cat as determined by the transganglionic transport of horseradish peroxidase. J Comp Neurol 203:785–798, 1981

    Google Scholar 

  17. Shigenaga Y, Chen LC, Suemune S, Nishimori T, Nasution ID, Yoshida A, Sato H, Okamoto T, Sera M, Hosoi M: Oral and facial representation within the medullary and upper cervical dorsal horns in the cat. J Comp Neurol 243:388–408, 1986

    Google Scholar 

  18. Shigenaga Y, Okamoto T, Nishimori T, Suemune S Nasution ID, Chen IC, Tsuru K, Yoshida A, Tabuchi K, Hosoi M, Tsuru H: Oral and facial representation in the trigeminal principal and rostral spinal nuclei of the cat. J Comp Neurol 244:1–18, 1986

    Google Scholar 

  19. Arviddson J, Hellstrand E: A horseradish peroxidase study of the central projections of primary trigeminal neurons innervating the hard palate in the cat. Brain Res 451:197–204, 1988

    Google Scholar 

  20. Liem RS, van Willigen JD, Copray JC, Ter Horst GJ: Corpuscular bodies in the palate of the rat. 2. Innervation and central projection. Acta Anatomica 138:65–74, 1990

    Google Scholar 

  21. Kruger L, Michel F: A morphological and somatotopic analysis of single unit activity in the trigeminal sensory complex of the cat. Exp Neurol 5:139–156, 1962

    Google Scholar 

  22. Kruger L, Michel F: A single neuron analysis of buccal cavity representation in the sensory trigeminal complex of the cat. Arch Oral Biol 7:491–503, 1962

    Google Scholar 

  23. Sessle BJ, Greenwood LF: Inputs to trigeminal brainstem neurones from facial, oral, tooth pulp and pharyngolaryngeal tissues: I. Responses to innocuous and noxious stimuli. Brain Res 117:211–226, 1976

    Google Scholar 

  24. Sessle BJ, Hu JW, Amano N, Zhong G: Convergence of cutaneous, tooth pulp, visceral, neck, and muscle afferents onto nociceptive and non-nociceptive neurones in trigeminal subnucleus caudalis (medullary dorsal horn) and its implications for referred pain. Pain 27:219–235, 1986

    Google Scholar 

  25. Kirkpatrick DB, Kruger L: Physiological properties of neurons in the principal sensory trigeminal nucleus of the cat. Exp Neurol 48:664–690

  26. Kruger L, Michel F: Reinterpretation of the representation of pain based on physiological excitation of single neurons in the trigeminal sensory complex. Exp Neurol 5:157–178, 1962

    Google Scholar 

  27. Azerad J, Woda A, Albe-Fessard D: Physiological properties of neurons in different parts of the cat trigeminal sensory complex. Brain Res 246:7–21, 1982

    Google Scholar 

  28. Eisenman J, Landgren S, Novin D: Functional organization in the main sensory trigeminal nucleus and in the rostral subdivision of the nucleus of the spinal trigeminal tract in the cat. Acta Physiol Scand 59 (Suppl 214):5–44, 1963

    Google Scholar 

  29. Bauer FA, Capra NF: Characteristics of subnucleus oralis neurons activated by periodontal mechanoreceptors (Abstract). J Dent Res 65:211, 1986

    Google Scholar 

  30. Ro JY, Capra NF: Receptive field properties of trigeminothalamic neurons in the rostral trigeminal sensory nuclei of cats. Somatosens Mot Res 11:119–130, 1994

    Google Scholar 

  31. Sweazey RD, Bradley RM: Response characteristics of lamb pontine neurons to stimulation of the oral cavity and epiglottis with different sensory modalities. J Neurophysiol 70:1168–1180, 1993

    Google Scholar 

  32. Sweazey RD, Bradley RM: Response characteristics of lamb trigeminal neurons to stimulation of the oral cavity and epiglottis with different sensory modalities. Brain Res Bull 22:883–891, 1989

    Google Scholar 

  33. Mountcastle VB: Central nervous system mechanism in mechanoreceptive sensibility. In: Brookhart JM, Mountcastle VB (eds.): Handbook of Physiology, section 1: The Nervous System, Vol 3, Sensory Processes, part 2. Bethesda, MD: American Physiological Society, 1984

    Google Scholar 

  34. Taber E: The cytoarchitecture of the brain stem of the cat. J Comp Neurol 116:27–69, 1961

    Google Scholar 

  35. Torvik A: The ascending fibers from the main trigeminal sensory nucleus: an experimental study in the cat. Am J Anat 100:1–51, 1957

    Google Scholar 

  36. Jones EG, Friedmann DP: Projection pattern of functional components of thalamic ventrobasal complex on monkey somatosensory cortex. J Neurophysiol 48:521–544, 1982

    Google Scholar 

  37. Jones EG: The Thalamus. New York, NY: Plenum Press, 1985, pp 325–374

    Google Scholar 

  38. Yasui Y, Itoh K, Mizuno N, Nomura S, Takada M, Konishi A, Kudo M: The ventroposteromedial nucleus of the thalamus (VPM) of the cat: direct ascending projections to the cytoarchitectonic subdivisions. J Comp Neurol 220:219–228, 1983

    Google Scholar 

  39. Burton H, Craig AD Jr: Distribution of trigeminothalamic cells in cat and monkey. Brain Res 161:515–521, 1979

    Google Scholar 

  40. Torvik A: Afferent connections to the sensory trigeminal nuclei, the nucleus of the solitary tract and adjacent structures. J Comp Neurol 106:51–141, 1956

    Google Scholar 

  41. Sweazey RD, Bradley RM: Responses of neurons in the lamb nucleus tractus solitarius to stimulation of the caudal oral cavity and epiglottis with different sensory modalities. Brain Res 48:133–150, 1989

    Google Scholar 

  42. Rossignol S, Lund JP, Drew T: The role of sensory inputs in regulating patterns of rhythmical movements in higher vertebrates. A comparison between locomotion, respiration, and mastication, In: Cohen A, Rossignol S, Grillner (eds.): Neural Control of Rhythmic Movements in Vertebrates. New York, NY: John Wiley and Sons, 1988, pp 201–283

    Google Scholar 

  43. Lund JP: Mastication and its control by the brain stem. Crit Rev Oral Biol Med 2:33–64, 1991

    Google Scholar 

  44. Jean A: Control of the central swallowing program by inputs from the peripheral receptors. A review. J Auton Nerv Sys 10:225–233, 1984

    Google Scholar 

  45. Doty RW: Influence of stimulus pattern on reflex deglutition. Am J Physiol 166:142–158, 1951

    Google Scholar 

  46. Miller AJ: Characteristics of the swallowing reflex induced by peripheral nerve and brainstem stimulation. Exp Neurol 34:210–222, 1972

    Google Scholar 

  47. Sinclair WJ: Role of the pharyngeal plexus in initiation of swallowing. Am J Physiol 221:1260–1263, 1971

    Google Scholar 

  48. Weerasuriya A, Bieger D, Hockman CH: Interaction between primary afferent nerves in the elicitation of reflex swallowing. Am J Physiol 239:R407-R414, 1980

    Google Scholar 

  49. Shingai T, Shimada K: Reflex swallowing elicited by water and chemical substances applied in the oral cavity, pharynx, and larynx of the rabbit. Jpn J Physiol 26:455–469, 1976

    Google Scholar 

  50. Miller FR, Sherrington CS: some observations on the buccopharyngeal stage of reflex deglutition in the cat. Quart J Exp Physiol 9:147–186, 1916

    Google Scholar 

  51. Pommerenke WT: A study of the sensory areas eliciting the swallowing reflex. Am J Physiol 84:36–41, 1928

    Google Scholar 

  52. Sinclair WJ: Initiation of reflex swallowing from the naso- and oropharynx. Am J Physiol 218:956–960, 1970

    Google Scholar 

  53. Mahan PE, Anderson KV: Interaction of tooth pulp and periodontal ligament receptors in the dog and monkey. Exp Neurol 33:441–443, 1971

    Google Scholar 

  54. Lazzara G, Lazarus C, Logemann JA: Impact of thermal stimulation on the triggering of the swallowing reflex. Dysphagia 1:73–77, 1986

    Google Scholar 

  55. Helfrich-Miller KR, Rector KL, Straka JA: Dysphagia: its treatment in the profoundly retarded patient with cerebral palsy. Arch Phys Med Rehabil 67:520–525, 1986

    Google Scholar 

  56. Logemann JA: Evaluation and Treatment of Swallowing Disorders. San Diego: College-Hill Press, 1983

    Google Scholar 

  57. Logemann JA: Treatment for aspiration related to dysphagia: an overview. Dysphagia 1:34–38, 1986

    Google Scholar 

  58. Rosenbek JC, Robbins J, Fishback B, Levine RL: Effects of thermal application on dysphagia after stroke. J Speech Hear Res 34:1257–1268, 1991

    Google Scholar 

  59. Chi-Fishman G, Capra NF, McCall GN: Thermomechanical facilitation of swallowing evoked by electrical nerve stimulation in cats. Dysphagia 9:149–155, 1994

    Google Scholar 

  60. Palmer JB, Rudin NJ, LaraG, Crompton AW: Coordination of mastication and swallowing. Dysphagia 7: 187–200

  61. Hiiemae KM, Crompton AW: Mastication, food transport, and swallowing. In: Hildebrand M, Bramble DM, Liem KL, Wake BD (eds.): Functional Vertebrate Morphology. Cambridge, MA: Harvard University Press, 1985, pp 262–290

    Google Scholar 

  62. Ringel RL: Studies of oral region texture perception. In: Bosma JF (ed.): Second Symposium on Oral Sensation and Perception. Springfield, IL: CT Thomas, 1970, pp 323–332

    Google Scholar 

  63. Graubard SA, Chialastri AJ: The relationship between oral stereognosis and the swallowing patterns in children. J Dent Child 46:35–41, 1979

    Google Scholar 

  64. McNutt JC: Asymmetry in two-point discrimination of the tongues of adults and children. J Commun Dis 8:213–220 1975

    Google Scholar 

  65. McDonald ET, Aungst LF: Apparent independence of oral sensory function and articulatory proficiency. In: Bosma JF (ed.): Second Symposium on Oral Sensation and Perception. Spring-field, IL: CT Thomas, 1970, pp 391–397

    Google Scholar 

  66. Kawamura Y, Morimoto T: Neurophysiological mechanisms related to reflex control of tongue movements. In: Bosma JF (ed.): Fourth Symposium on Oral Sensation and Perception: Development of the Fetus and Infant. Bethesda, MD: DHEW, National Institutes of Health, 1973, pp 206–217

    Google Scholar 

  67. Sessle BJ, Kenny DJ: Control of tongue and facial motility: neural mechanisms that may contribute to movements such as swallowing and sucking. In: Bosma JF (ed.): Fourth Symposium on Oral Sensation and Perception: Development of the Fetus and Infant. Bethesda, MD: DHEW, National Institutes of Health, 1973, pp 222–231

    Google Scholar 

  68. Sumi T: Importance of pharyngeal feedback on the integration of reflex deglutition in newborn animals. In: Bosma JF (ed.): Fourth Symposium on Oral Sensation and Perception: Development of the Fetus and Infant. Bethesda, MD: DHEW, National Institutes of Health, 1973, pp 174–184

    Google Scholar 

  69. Sumino R, Nakamura Y: Control of tongue and facial motility: neural mechanisms that may contribute to movements such as swallowing and sucking. In: Bosma JF (ed.) Fourth Symposium on Oral Sensation and Perception: Development of the Fetus and Infant. Bethesda, MD: DHEW, National Institutes of Health, 1973, pp 218–221

    Google Scholar 

  70. Malinovsky L: What is a sensory corpuscle? In: Hnik P, Soukup T, Vejsada, Zelená J (eds.): Mechanoreceptors Development, Structure, and Function. New York, NY: Plenum, 1988, pp 283–286

    Google Scholar 

  71. Hiatt JL, Gartner LP: Textbook of Head and Neck Anatomy. Baltimore, MD: Williams and Wilkins, p 50, 1987

    Google Scholar 

  72. Mountcastle VB: Neural mechanisms in somesthesia. In: Mountcastle VB (ed): Medical Physiology, Vol. 1, St Louis, MO: Mosby, 1974, p 317

    Google Scholar 

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  1. Department of Oral and Craniofacial Biological Science, University of Maryland Dental School, 666 W. Baltimore St., 21201, Baltimore, MD, USA

    Norman F. Capra PhD

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  1. Norman F. Capra PhD
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Capra, N.F. Mechanisms of oral sensation. Dysphagia 10, 235–247 (1995). https://doi.org/10.1007/BF00431416

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