Skip to main content
SpringerLink
Log in

A fine-structure map of the yeast L-asparaginase gene

  • Published:
Molecular and General Genetics MGG Aims and scope Submit manuscript

Summary

A fine-structure map containing 14 mutational sites in the yeast L-asparaginase gene has been constructed by using X-ray-stimulated mitotic reversion. From this map is deduced a minimum molecular weight of each L-asparaginase polypeptide monomer (8 200 to 10 000) and a minimum size of the yeast L-asparaginase gene (225–270 nucleotide pairs).

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Esposito, M. S.: X-ray and meiotic fine structure mapping of the adenine-8 locus in Saccharomyces cerevisiae. Genetics 58, 507–527 (1968).

    Google Scholar 

  • Fogel, S., Mortimer, R. K.: Recombination in yeast. Ann. Rev. Genet. 5, 219–236 (1971).

    Google Scholar 

  • Hawthorne, D. C., Mortimer, R. K.: Chromosome mapping in Saccharomyces: centromere-linked genes. Genetics 45, 1085–1110 (1960).

    Google Scholar 

  • Jones, G. E.: L-Asparagine degradation in Saccharomyces cerevisiae: genetic control and biochemical properties of yeast L-asparaginase. Ph. D. Dissertation, University of California, Berkeley, UCRL-19480 (1970).

    Google Scholar 

  • Jones, G. E., Mortimer, R. K.: L-Asparaginase-deficient mutants of yeast. Science 167, 181–182 (1970).

    Google Scholar 

  • Jones, G. E., Mortimer, R. K.: Biochemical properties of yeast L-asparaginase. Submitted to Biochemical Genetics (1972).

  • Lemontt, J. F.: Mutants of yeast deficient in mutation induced by ultraviolet light. Genetics 68, 21–33 (1971).

    Google Scholar 

  • Manney, T. R., Mortimer, R. K.: Allelic mapping in yeast by X-ray-induced mitotic reversion. Science 143, 581–583 (1964).

    Google Scholar 

  • Mortimer, R. K.: Invited discussion. Radiat. Res., Suppl. 1, 394–402 (1959).

    Google Scholar 

  • Mortimer, R. K., Hawthorne, D. C.: Yeast genetics. In: A. H. Rose and J. S. Harrison (eds.), The yeasts, vol. 1, p. 385–460. New York: Academic Press 1969.

    Google Scholar 

  • Parker, J. H., Sherman, F.: Fine-structure mapping and mutational studies of genes controlling yeast cytochrome c. Genetics 62, 9–22 (1969).

    Google Scholar 

  • Robichon-Szulmajster, H. de, Surdin, Y., Mortimer, R. K.: Genetic and biochemical studies of genes controlling the synthesis of threonine and methionine in Saccharomyces. Genetics 53, 609–619 (1966).

    Google Scholar 

  • Sledecor, G. W.: Statistical methods, 5. ed., Ames, Iowa: Iowa State University Press 1956.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Division of Medical Physics, University of California, Berkeley, California, USA

    Gary E. Jones

  2. Department of Genetics, The Hospital for Sick Children, 555 University Avenue, Toronto 2, Ontario, Canada

    Gary E. Jones

Authors
  1. Gary E. Jones
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Communicated by F. Stahl

Rights and permissions

Reprints and permissions

About this article

Cite this article

Jones, G.E. A fine-structure map of the yeast L-asparaginase gene. Molec. gen. Genet. 121, 9–14 (1973). https://doi.org/10.1007/BF00353689

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00353689

Keywords

Search

Navigation