Abstract
Measurements of stroke volume (SV) by echo-Doppler techniques (2D-echocardiography, continuous and pulsed Doppler) were compared to those obtained by thermodilution in 116 critically ill patients. The best correlation was obtained with pulsed Doppler positioned in the left ventricular (LV) outflow (r=0,78, p<0.001). In a subgroup of 12 patients who had LV ejection fraction < 60% and LV end-diastolic pressure > 15 mmHg, we also measured the peak aortic blood velocity (PABV) and acceleration (PABA) by continuous and pulsed Doppler as indexes of myocardial contractility before coronary artery bypass graft. When compared to healthy volunteers, these patients had decreased PABV and PABA, measured by continuous Doppler (91±16 vs 79±9 cm/s, p<0.05 and 913±202 vs 660±149 cm/s/s, p<0.05, respectively). These data therefore indicate that in critically ill patients pulsed Doppler placed in the LV outflow is an adequate echo-Doppler technique to measure SV, while continuous Doppler placed in the suprasternal notch can be used to assess LV performance.
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References
Light H (1976) Transcutaneous aortovelography. A new window on the circulation? Br Heart J 38:433
Loeppky JA, Greene ER, Hoekenga DE, Caprihan A, Luft UC (1981) Beat-by-beat stroke volume assessment by pulsed Doppler in upright and supine exercise. J Appl Physiol 50:1173
Goldberg SJ, Loeber CP (1983) Can Doppler velocities measured anywhere in the aortic arch be substituted for ascending aortic velocities? Circulation 68[Suppl.3]:260
Huntsman LL, Stewart DK, Barnes SR, Franklin SB, Colocousis JS, Hessel ER (1983) Non-invasive Doppler determination of cardiac output in man. Circulation 67:593
Levy BI, Payen DM, Tedgui A, Xhaard M, McIlroy MB (1985) Non-invasive ultrasonic cardiac output measurement in intensive care unit. Ultrasound Med Biol 11:841
Vandenbogaerde JF, Scheldewaert RG, Rejckaert DL, Clement DL, Colardyn FA (1986) Comparison between ultrasonic and thermodilution cardiac output measurements in intensive care patients. Crit Care Med 14:294
Alazraki NP, Schelbert HR, Verba JW, Brock GW, Johnson AD, Ashburn WL (1975) Utilization of the radionuclide cardiac angiogram for determination of cardiac output and ejection fraction. J Nucl Med 19:127
Wexler JP, Blaufox MD (1979) Radionuclide evaluation of left ventricular function with nonimaging probes. Semin Nucl Med 9:310
Bennett ED, Barclay SA, Davis AL, Mannering D, Mehta N (1984) Ascending aortic blood velocity and acceleration using Doppler ultrasound in the assessment of left ventricular function. Cardiovasc Res 18:632
Sabbah HN, Khaja F, Brymer JF, McFarland TM, Albert DE, Snyder JE (1986) Non-invasive evaluation of left ventricular performance based on peak aortic blood acceleration measured with a continuous-wave Doppler velocity meter. Circulation 74:323
Gueret P, Meerbaum S, Wyatt HL, Uchiyama T, Lang TW, Corday E (1980) Two-dimensional echocardiographic quantitation of left ventricular volumes and ejection fraction. Circulation 62:1308
Folland ED, Parisi AF, Moynihan PF, Jones DR, Feldman CL, Two DE (1979) Assessment of left ventricular ejection fraction and volumes by real-time, two-dimensional echocardiography: a comparison of cineangiographic and radionuclide techniques. Circulation 60:760
Stevens HJ, Raffin TA, Mihm FG, Rosenthal MH, Stetz CW (1985) Thermodilution cardiac output measurement: effects of respiratory cycle on its reproducibility. JAMA 253:2240
Daper A, Parquier JN, Preiser JC, Contempre B, Vincent JL (1986) Timing of cardiac output measurements during mechanical ventilation. Acute Care 12:113
Lewis JF, Kuo LC, Nelson JG, Limacher MC, Quinones MR (1984) Pulsed Doppler echocardiographic determination of stroke volume and cardiac output: clinical validation of two new methods using the apical window. Circulation 70:425
Fischer DC, Sahn DJ, Friedman MJ, Larson DL, Valdez-Cruz L, Horowitz S (1983) The effect of variations on Pulsed Doppler sampling site on calculation of cardiac output: an experimental study in open-chest dogs. Circulation 67:370
Donovan KD, Dobb GJ, Newman MA, Hockings BES, Ireland M (1987) Comparison of pulsed Doppler and thermodilution method for measuring cardiac output in critically ill patients. Crit Care Med 15:853
Schuster AH, Nanda NC (1984) Doppler echocardiographic measurement of cardiac output: comparison with a non-golden standard. Am J Cardiol 53:257
MacKenzie JD, Haites NE, Rawles JM (1986) Method of assessing the reproducibility of blood flow measurement: factors influencing the performance of thermodilution cardiac output computers. Br Heart J 55:14
Schuster AH, Nanda NC (1984) Doppler echocardiography Part I Doppler cardiac output measurements: perspective and comparison with other methods of cardiac output determination. Echocardiography 1:45
Gardin JM, Burn CS, Childs WJ, Henry WL (1984) Evaluation of blood flow velocity in the ascending aorta and main pulmonary artery of normal subjects by Doppler echocardiography. Am Heart J 107:310
Lambert CHR, Nichols WW, Pepine CJ (1983) Indices of ventricular contractile state: comparative sensitivity and specificity. Am Heart J 106:136
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Goldstein, M., Vincent, J.L. & Kahn, R.J. Evaluation of cardiac function by echo-Doppler studies in critically ill patients. Intensive Care Med 14, 406–410 (1988). https://doi.org/10.1007/BF00262897
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DOI: https://doi.org/10.1007/BF00262897