Abstract
Bone scans and X-rays from 23 subjects with symptomatic Paget's disease were evaluated. One-hundred and twenty-seven sites of Pagetoid involvement were found, of which 120 (94.5%) were recognised on the bone scan as compared to 94 (74%) on X-ray. The anatomical distribution and relationship of lesions on scan and X-ray to the patient's symptoms are also discussed.
It is concluded that the bone scan is more sensitive than radiology in detecting Paget's disease and only rarely will a lesion that is seen on X-ray not be visualised by scanning.
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Citrin, D.L., McKillop, J.H. Paget's disease In: Atlas of Technetium bone scans, p. 126. Philadelphia: W.B. Saunders 1978
Collins, D.H.: Paget's disease of bone. Incidence and subclinical forms. Lancet 2, 51–57 (1956)
Fogelman, I., Carr, D.: A comparison of bone scanning and radiology in the evaluation of patients with metabolic bone disease. Clin. Radiol. 31, 321–326 (1980)
Fogelman, I., McKillop, J.H., Bessent, R.G., Boyle, I.T., Turner, J.G., Greig, W.R.: The role of bone scanning in osteomalacia. J. Nucl. Med. 19, 245–248 (1978)
Ibbertson, H.K., Henley, J.W., Fraser, T.R., Tait, B., Stephens, E.J., Scot, D.J.: Paget's disease of bone—Clinical evaluation and treatment with diphosphonate. Aust. N.Z.J. Med. 9, 31–35 (1979)
Khairi, M.R., Rob, J.A., Wellman, H.N., Johnston, C.C. Jr: Radiographs and scans in diagnosing symptomatic lesions of Paget's disease of bone (osteitis deformans). Geriatrics 29, 49–54 (1974)
Khairi, M.R., Wellman, H.N., Robb, J.A., Johnston, C.C. Jr: Paget's disease of bone (osteitis deformans): symptomatic lesions and bone scan. Ann. Int. Med. 79, 348–351 (1973)
Lavender, J.P., Evans, I.M., Arnot, R., Bowring, S., Doyle, F.H., Joplin, C.F., MacIntyre, I.: A comparison of radiography and radioisotope scanning in the detection of Paget's disease and in the assessment of response to human calcitonin. Br. J. Radiol. 50, 243–250 (1977)
Miller, S.W., Castronovo, F.P.Jr., Pendergrass, H.R., Potsaid, M.S.: Technetium 99m labelled diphosphonate bone scanning in Paget's disease. Am. J. Roentgenol. 121, 177–183 (1974)
Milstein, D., Nusynowitz, M.L., Lull, R.J.: Radionuclide diagnosis in chest disease resulting from trauma. Semin. Nucl. Med. 4, 339–355 (1974)
Serafini, A.N.: Paget's disease of bone. Semin. Nucl. Med. 6, 47–58 (1976)
Shirazi, P.H., Ryan, W.G., Fordham, E.W.: Bone scanning in evaluation of Paget's disease of bone. CRC Crit. Rev. Clin. Radiol. Nucl. Med. 5, 523–558 (1974)
Vellenga, C.J., Pauwels, E.K., Bijvoet, O.L., Hosking, D.J.: Evaluation of scintigraphic and roentgenologic studies in Paget's disease under treatment. Radiol. Clin. (Basel) 45, 292–301 (1976)
Wellman, H.N., Schauwecker, D., Robb, J.A., Khairi, M.R., Johnston, C.C.: Skeletal scintimaging and radiography in the diagnosis and management of Paget's disease. Clin. Orthop. 127, 55–62 (1977)
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Fogelman, I., Carr, D. A comparison of bone scanning and radiology in the assessment of patients with symptomatic Paget's disease. Eur J Nucl Med 5, 417–421 (1980). https://doi.org/10.1007/BF00261784
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DOI: https://doi.org/10.1007/BF00261784