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Cardiotoxic effects of antitumor agents

  • Short Review
  • Cardiotoxic Agents
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Summary

Cardiotoxic effects related to treatment with some antitumor agents (chiefly anthracycline antibiotics, cyclophosphamide, corticosteroids, 5-fluorouracil, and radiation therapy), their association, and contemporaneous administration of other (potentially) cardiotoxic drugs are reviewed.

Experimental models, clinical findings, and diagnostic methods are briefly described.

Pathogenetic factors and interactions of antitumor drugs with biomembranes, DNA, and immune reactions are discussed.

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    Mario Ghione

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Ghione, M. Cardiotoxic effects of antitumor agents. Cancer Chemother. Pharmacol. 1, 25–34 (1978). https://doi.org/10.1007/BF00253143

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