Summary
Experimental data on the pharmacokinetic, toxic and therapeutic properties of daunorubicin-DNA and doxorubicin-DNA complexes are reviewed and summarized as well as the available reports on clinical trials performed with these anthracycline-DNA complexes.
These results are discussed in view of the further development of the drug-carrier concept of cancer chemotherapy.
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Trouet, A., Deprez-De Campeneere, D. Daunorubicin-DNA and doxorubicin-DNA a review of experimental and clinical data. Cancer Chemother. Pharmacol. 2, 77–79 (1979). https://doi.org/10.1007/BF00253110
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DOI: https://doi.org/10.1007/BF00253110