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The healing of flexor tendons in chickens

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Summary

The healing of flexor tendons was studied in chickens using transmission electron microscopy. After resecting the flexor sheath between the proximal and distal pulleys in zone II, the profundus tendon was severed and sutured. Intermittent passive motion was carried out 35 times daily immediately afterwards. The chickens were sacrificed at 3, 6 and 9 weeks. In vivo healing was shown to be much more rapid than in in vitro studies. There was marked proliferation of endoplasmic reticulum and phagocytosis at 3 weeks, collagen synthesis at 6 weeks and remodelling at 9 weeks. Healing was by a combination of extrinsic and intrinsic mechanisms.

Résumé

Le processus de cicatrisation des tendons fléchisseurs a été étudié chez le poulet en utilisant la microscopie électronique. Le modèle de plaie tendineuse a été réalisé par suture du tendon fléchisseur profond sectionné, aprés résection de la gaine entre les poulies distale et proximale, en zone II. Une mobilisation passive intermittente a été entreprise immédiatement aprés la réparation, au rythme de 35 fois par jour. Les poulets ont été sacrifiés à la troisième, sixième et neuvième semaine et on a étudié les modifications cellulaires au niveau de la zone suturée. Les résultats montrent que la cicatrisation est plus rapide in vivo qu'in vitro. On a observé à trois semaines une prolifération marquée du rétinaculum endoplasmique dans les cellules de l'endotendon et une phagocytose par des cellules de type périphérique, à six semaines une synthèse du collagène et à neuf semaines un remodelage du collagène. La cicatrisation tendineuse est une combinaison de mécanismes de reconstruction extrinsèques et intrinsèques.

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Siddiqi, N.A., Hamada, Y. & Noryia, A. The healing of flexor tendons in chickens. International Orthopaedics 16, 363–368 (1992). https://doi.org/10.1007/BF00189620

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  • DOI: https://doi.org/10.1007/BF00189620

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