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Isolation of the human T-cell leukemia/lymphotropic virus type III from aqueous humor in two patients with perivasculitis of the retinal vessels

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Summary

The human T-cell leukemia/lymphotropic virus type III (HTLV-III) has been isolated from aqueous humor in two patients with perivasculitis of the peripheral retinal vessels, an AIDS-related ocular manifestation. Both patients had antibodies to HTLV-III and although they presented with herpes zoster ophthalmicus, they did not present other symptoms known to be associated with HTLV-III infection. The isolation of HTLV-III from aqueous humor in these two patients with retinal perivasculitis suggests that the virus itself may play a role in the etiology of this ocular sign. The presence of infectious HTLV-III in the anterior chamber further emphasises the necessity to discard corneas from HTLV-III infected donors.

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Authors and Affiliations

  1. Department of Ophthalmology, Centre Hospitalier de Kigali, Rwanda

    Philippe Kestelyn

  2. AIDS project Rwanda, Rwanda

    Philippe Van de Perre

  3. Department of Virology, Institut Pasteur du Brabant, Brussels, Belgium

    Suzy Sprecher-Goldberger

Authors
  1. Philippe Kestelyn
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  2. Philippe Van de Perre
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  3. Suzy Sprecher-Goldberger
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Additional information

Address for offprints: Mrs Suzy Sprecher-Goldberger, Institut Pasteur du Brabant, rue Engeland 642, Bruxelles/Uccle Belgium

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Kestelyn, P., Van de Perre, P. & Sprecher-Goldberger, S. Isolation of the human T-cell leukemia/lymphotropic virus type III from aqueous humor in two patients with perivasculitis of the retinal vessels. Int Ophthalmol 9, 247–251 (1986). https://doi.org/10.1007/BF00137538

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