Skip to main content
SpringerLink
Log in

Advances in the Bioremediation of Pharmaceuticals and Personal Care Products (PPCPs): Polluted Water and Soil

  • Chapter
  • First Online:
Microbial Products for Health, Environment and Agriculture

Part of the book series: Microorganisms for Sustainability ((MICRO,volume 31))

Abstract

Pharmaceutical and personal care products (PPCPs) comprising a variety of organic categories, like antibiotics, hormones, antimicrobials, synthetic musks, etc., have promoted significant interest in recent times that their constant input of such substances has become a serious threat to the public and the environment, extending from surface water, sludge, sewage, aquatic bodies, treatment plants, sediments, soil, humans, and wildlife. In recent years, the existence of PPCPs has been attracting growing focus, leading to considerable concern about their frequency, development, fate, and danger in the ecosystems. However, in recent years the substantial use of such molecules has contributed to their accumulation in our ecosystem, and they are now observed in living organisms via their intervention in food chains and food webs. As bioactive in nature, these substances have significant toxicological and precarious impacts on ecological systems, environments, and human health. A number of methodologies have been widely studied for eliminating PPCPs from the environment, including physical, biological, and chemical methods. The categories, functions, and representatives of the commonly observed PPCPs within the environments were stated in this chapter. This chapter also structured to explicate the incidence, fate, and bioremediation (BR) of PPCPs from waste water and soil utilizing microorganisms (MOs) and plants, and also the experimental methods used to assess the PPCPs in nature.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Abbreviations

ACC:

1-Aminocyclopropane-1-carboxylate

AChE:

Acetylcholinesterase

ATN:

Artemisine

BTF:

Biotransformation

CBZ:

Carbamazepine

CDN:

Codeine

CFN:

Caffeine

CSCM:

Circular supply chain management

CWs:

Constructed wetlands

DFC:

Diclofenac

DOS:

Dioctyl sebacate

E2α:

17α-Ethinylestradiol

EROD:

Ethoxyresorufin-O-deethylase

EST:

Estradiol

FLU:

Flumequine

GC:

Gas chromatography

GFZ:

Gemfibrozil

HPLC:

High-performance liquid chromatography

HRAP:

High rate algal pond

HRT:

Hydraulic retention time

IBU:

Ibuprofen

LLE:

Liquid–liquid extraction

LLME:

Liquid–liquid micro-extraction

MBR:

Membrane bioreactors

MCs:

Mixed cultures

NP:

Nonylphenol

NPX:

Naproxen

PGPH:

Plant growth-promoting hormone

PPCPs:

Pharmaceuticals and personal care products

ROS:

Reactive oxygen species

SDG:

Sustainable development goal

SMX:

Sulfamethoxazole

SPE:

Solid-phase extraction

SPME:

Solid-phase micro-extraction

STP:

Sewage treatment plants

TCS:

Triclosan

UV:

Ultraviolet

WRF:

White rot fungi

WWTP:

Wastewater treatment plants

References

  • Abd El-Hakim YM, Mohamed WA, El-Metwally AE (2018) Spirulina platensis attenuates furan reprotoxicity by regulating oxidative stress, inflammation, and apoptosis in testis of rats. Ecotoxicol Environ Saf 161:25–33

    Article  CAS  PubMed  Google Scholar 

  • Afzal M, Khan QM, Sessitsch A (2014) Endophytic bacteria: prospects and applications for the phytoremediation of organic pollutants. Chemosphere 117:232–242

    Article  CAS  PubMed  Google Scholar 

  • Aherne GW, Hardcastle A, Nield A (1990) Cytotoxic drugs and the aquatic environment: estimation of bleomycin in river and water samples. J Pharm Pharmacol 42:741–742

    Article  CAS  PubMed  Google Scholar 

  • Al-Ansari AM, Saleem A, Kimpe LE et al (2010) Bioaccumulation of the pharmaceutical 17α-ethinylestradiol in shorthead redhorse suckers (Moxostoma macrolepidotum) from the St. Clair River, Canada. Environ Pollut 158:2566–2571

    Article  CAS  PubMed  Google Scholar 

  • Al-Farsi RS, Ahmed M, Al-Busaidi A, Choudri BS (2017) Translocation of pharmaceuticals and personal care products (PPCPs) into plant tissues: a review. Emerg Contam 3:132–137

    Article  Google Scholar 

  • Ali MEM, Abd El-Aty AM, Badawy MI, Ali RK (2018) Removal of pharmaceutical pollutants from synthetic wastewater using chemically modified biomass of green alga Scenedesmus obliquus. Ecotoxicol Environ Saf 151:144–152

    Article  CAS  PubMed  Google Scholar 

  • Aracagok YD, Goker H, Cihangir N (2017) Biodegradation of micropollutant naproxen with a selected fungal strain and identification of metabolites. Z Naturforsch 72:173–179

    Article  CAS  Google Scholar 

  • Aracagok YD, Goker H, Cihangir N (2018) Biodegradation of diclofenac with fungal strains. Arch Environ Prot 44:55–62

    CAS  Google Scholar 

  • Ardao I, Magnin D, Agathos SN (2015) Bioinspired production of magnetic laccase-biotitania particles for the removal of endocrine disrupting chemicals. Biotechnol Bioeng 112:1986–1996

    Article  CAS  PubMed  Google Scholar 

  • Ashton D, Hilton M, Thomas KV (2004) Investigating the environmental transport of human pharmaceuticals to streams in the United Kingdom. Sci Total Environ 333:167–184

    Article  CAS  PubMed  Google Scholar 

  • Asif MB, Hai FI, Singh L, Price WE et al (2017) Degradation of pharmaceuticals and personal care products by white-rot fungi-a critical review. Curr Pollut Rep 3:88–103

    Article  CAS  Google Scholar 

  • Awad YM, Ok YS, Igalavithana AD et al (2016) Sulphamethazine in poultry manure changes carbon and nitrogen mineralisation in soils. Chem Ecol 32:899–918

    Article  CAS  Google Scholar 

  • Bai X, Acharya K (2019) Removal of seven endocrine disrupting chemicals (EDCs) from municipal wastewater effluents by a freshwater green alga. Environ Pollut 247:534–540

    Article  CAS  PubMed  Google Scholar 

  • Bai N, Wang S, Sun P et al (2018) Degradation of nonylphenol polyethoxylates by functionalized Fe3O4 nanoparticle-immobilized Sphingomonas sp. Y2. Sci Total Environ 615:462–468

    Article  CAS  PubMed  Google Scholar 

  • Barac T, Taghavi S, Borremans B et al (2004) Engineered endophytic bacteria improve phytoremediation of water-soluble, volatile, organic pollutants. Nat Biotechnol 22:583–588

    Article  CAS  PubMed  Google Scholar 

  • Barth S, Fischer M, Schmid RD, Pleiss J (2004) Sequence and structure of epoxide hydrolases: a systematic analysis. Proteins Struct Funct Genet 55:846–855

    Article  CAS  PubMed  Google Scholar 

  • Bhatnagar N, Bhatnagar N (2013) Phytoremediation: a promising Technology of Environmental Pollution Control. Glob J Microb Biotechnol 4:39–42

    Google Scholar 

  • Blair BD, Crago JP, Hedman CJ, Klaper RD (2013) Pharmaceuticals and personal care products found in the Great Lakes above concentrations of environmental concern. Chemosphere 93:2116–2123

    Article  CAS  PubMed  Google Scholar 

  • Bodin H, Daneshvar A, Gros M, Hultberg M (2016) Effects of biopellets composed of microalgae and fungi on pharmaceuticals present at environmentally relevant levels in water. Ecol Eng 91:169–172

    Article  Google Scholar 

  • Borova VL, Maragou NC, Gago-Ferrero P et al (2014) Highly sensitive determination of 68 psychoactive pharmaceuticals, illicit drugs, and related human metabolites in wastewater by liquid chromatography–tandem mass spectrometry. Anal Bioanal Chem 406:4273–4285

    Article  CAS  PubMed  Google Scholar 

  • Boxall A, Rudd MA, Brooks BW et al (2012) Pharmaceuticals and personal care products in the environment: what are the big questions? Environ Health Perspect 120:1221–1229

    Article  PubMed  PubMed Central  Google Scholar 

  • Brausch JM, Rand GM (2011) A review of personal care products in the aquatic environment: environmental concentrations and toxicity. Chemosphere 82:1518–1532

    Article  CAS  PubMed  Google Scholar 

  • Bronikowski A, Hagedoorn PL, Koschorreck K, Urlacher VB (2017) Expression of a new laccase from Moniliophthora roreri at high levels in Pichia pastoris and its potential application in micropollutant degradation. AMB Express 7:73

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Buchicchio A, Bianco G, Sofo A et al (2016) Biodegradation of carbamazepine and clarithromycin by Trichoderma harzianum and Pleurotus ostreatus investigated by liquid chromatography - high-resolution tandem mass spectrometry (FTICR MS-IRMPD). Sci Total Environ 557:733–739

    Article  PubMed  CAS  Google Scholar 

  • Bundschuh M, Hahn T, Gessner MO, Schulz R (2009) Antibiotics as a chemical stressor affecting an aquatic decomposer–detritivore system. Environ Toxicol Chem 28:197–203

    Article  CAS  PubMed  Google Scholar 

  • Cabana H, Jones JP, Agathos SN (2007) Elimination of endocrine disrupting chemicals using white rot fungi and their lignin modifying enzymes: a review. Eng Life Sci 7:429–456

    Article  CAS  Google Scholar 

  • Cai MQ, Wang R, Feng L, Zhang LQ (2015) Determination of selected pharmaceuticals in tap water and drinking water treatment plant by high-performance liquid chromatography-triple quadrupole mass spectrometer in Beijing, China. Environ Sci Pollut Res 22:1854–1867

    Article  CAS  Google Scholar 

  • Cajthaml T, Kresinova Z, Svobodova K, Moder M (2009) Biodegradation of endocrine-disrupting compounds and suppression of estrogenic activity by ligninolytic fungi. Chemosphere 75:745–750

    Article  CAS  PubMed  Google Scholar 

  • Caldwell DJ, Mastrocco F, Margiotta-Casaluci L, Brooks BW (2014) An integrated approach for prioritizing pharmaceuticals found in the environment for risk assessment, monitoring and advanced research. Chemosphere 115:4–12

    Article  CAS  PubMed  Google Scholar 

  • Calheiros CSC, Bessa VS, Mesquita RBR et al (2015) Constructed wetland with a polyculture of ornamental plants for wastewater treatment at a rural tourism facility. Ecol Eng 79:1–7

    Article  Google Scholar 

  • Camacho-Morales RL, Gerardo-Gerardo JL, Guillen Navarro K, Sanchez JE (2017) Ligninolytic enzyme production by white rot fungi during paraquat (herbicide) degradation. Rev Argent Microbiol 49:189–196

    PubMed  Google Scholar 

  • Carballa M, Omil F, Lema JM et al (2004) Behavior of pharmaceuticals, cosmetics and hormones in a sewage treatment plant. Water Res 38:2918–2926

    Article  CAS  PubMed  Google Scholar 

  • Carmona E, Andreu V, Pico Y (2014) Occurrence of acidic pharmaceuticals and personal care products in Turia River basin: from waste to drinking water. Sci Total Environ 484:53–63

    Article  CAS  PubMed  Google Scholar 

  • Carr HY, Purcell EM (1954) Effects of diffusion on free precession in nuclear magnetic resonance experiments. Phys Rev 94:630–638

    Article  CAS  Google Scholar 

  • Castellet-Rovira F, Lucas D, Villagrasa M et al (2018) Stropharia rugosoannulata and Gymnopilus luteofolius: promising fungal species for pharmaceutical biodegradation in contaminated water. J Environ Manag 207:396–404

    Article  CAS  Google Scholar 

  • Chatterjee A, Abraham J (2019) Mycoremediation of 17β-estradiol using Trichoderma citrinoviride strain AJAC3 along with enzyme studies. Environ Prog Sustain Energy 8:13142

    Article  CAS  Google Scholar 

  • Chen RZ, Wong MH (2016) Integrated wetlands for food production. Environ Res 426:13–31

    Google Scholar 

  • Chen W, Lu S, Jiao W et al (2013) Reclaimed water: a safe irrigation water source? Environ Dev 8:74–83

    Article  Google Scholar 

  • Chiron S, Minero C, Vione D (2006) Photodegradation processes of the antiepileptic drug carbamazepine, relevant to estuarine waters. Environ Sci Technol 40:5977–5983

    Article  CAS  PubMed  Google Scholar 

  • Cirja M, Hommes G, Ivashechkin P et al (2009) Impact of bio-augmentation with Sphingomonas sp. strain TTNP3 in membrane bioreactors degrading nonylphenol. Appl Microbiol Biotechnol 84:183–189

    Article  CAS  PubMed  Google Scholar 

  • Cizmas L, Sharma VK, Gray CM, McDonald TJ (2015) Pharmaceuticals and personal care products in waters: occurrence, toxicity, and risk. Environ Chem Lett 13:381–394

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Cleuvers M (2008) Chronic mixture toxicity of pharmaceuticals to daphnia—the example of nonsteroidal anti-inflammatory drugs. In: Kümmerer K (ed) Pharmaceuticals in the environment: sources, fate, effects and risks. Springer, Berlin Heidelberg, pp 277–284

    Chapter  Google Scholar 

  • Coimbra RN, Escapa C, Vazquez NC et al (2018) Utilization of non-living microalgae biomass from two different strains for the adsorptive removal of diclofenac from water. Water 10:1401

    Article  CAS  Google Scholar 

  • Combalbert S, Hernandez-Raquet G (2010) Occurrence, fate, and biodegradation of estrogens in sewage and manure. Appl Microbiol Biotechnol 86:1671–1692

    Article  CAS  PubMed  Google Scholar 

  • Conkle JL, Gan J, Anderson MA (2012) Degradation and sorption of commonly detected PPCPs in wetland sediments under aerobic and anaerobic conditions. J Soils Sediments 12:1164–1173

    Article  CAS  Google Scholar 

  • Corcoran J, Winter MJ, Tyler CR (2010) Pharmaceuticals in the aquatic environment: a critical review of the evidence for health effects in fish. Crit Rev Toxicol 40:287–304

    Article  CAS  PubMed  Google Scholar 

  • Cruz-Morato C, Ferrando-Climent L, Rodriguez-Mozaz S et al (2013) Degradation of pharmaceuticals in non-sterile urban wastewater by Trametes versicolor in a fluidized bed bioreactor. Water Res 47:5200–5210

    Article  CAS  PubMed  Google Scholar 

  • Cvancarova M, Moeder M, Filipova A et al (2013) Biotransformation of the antibiotic agent flumequine by ligninolytic fungi and residual antibacterial activity of the transformation mixtures. Environ Sci Technol 47:14128–14136

    Article  CAS  PubMed  Google Scholar 

  • Czarny K, Szczukocki D, Krawczyk B (2019) Toxic effects of single animal hormones and their mixtures on the growth of Chlorella vulgaris and Scenedesmus armatus. Chemosphere 224:93–102

    Article  CAS  PubMed  Google Scholar 

  • da Luz JMR, Paes SA, Torres DP et al (2013) Production of edible mushroom and degradation of antinutritional factors in jatropha biodiesel residues. LWT Food Sci Technol 50:575–580

    Article  CAS  Google Scholar 

  • Daughton CG, Ternes TA (1999) Pharmaceuticals and personal care products in the environment: agents of subtle change? Environ Health Perspect 107:907–938

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • de Godos I, Munoz R, Guieysse B (2012) Tetracycline removal during wastewater treatment in high-rate algal ponds. J Hazard Mater 229:446–449

    Article  PubMed  CAS  Google Scholar 

  • de las Heras I, Padrino B, Molina R et al (2017) Efficient treatment of synthetic wastewater contaminated with emerging pollutants by anaerobic purple phototrophic bacteria. Front Wastewater Treat Model 1:324–330

    Article  Google Scholar 

  • de Siqueira Castro J, Calijuri ML, Mattiello EM et al (2020) Algal biomass from wastewater: soil phosphorus bioavailability and plants productivity. Sci Total Environ 711:135088

    Article  CAS  Google Scholar 

  • Deng Y, Mao Y, Li B et al (2016) Aerobic degradation of sulfadiazine by arthrobacter spp.: kinetics, pathways, and genomic characterization. Environ Sci Technol 50:9566–9575

    Article  CAS  PubMed  Google Scholar 

  • Devatha CP, Pavithra N (2019) Isolation and identification of Pseudomonas from wastewater, its immobilization in cellulose biopolymer and performance in degrading Triclosan. J Environ Manag 232:584–591

    Article  CAS  Google Scholar 

  • Diaz-Cruz MS, Barcelo D (2008) Trace organic chemicals contamination in ground water recharge. Chemosphere 72:333–342

    Article  CAS  PubMed  Google Scholar 

  • Ding T, Yang M, Zhang J et al (2017) Toxicity, degradation and metabolic fate of ibuprofen on freshwater diatom Navicula sp. J Hazard Mater 330:127–134

    Article  CAS  PubMed  Google Scholar 

  • Dolphen R, Thiravetyan P (2019) Reducing arsenic in rice grains by leonardite and arsenic–resistant endophytic bacteria. Chemosphere 223:448–454

    Article  CAS  PubMed  Google Scholar 

  • Dubroca J, Brault A, Kollmann A et al (2005) Biotransformation of nonylphenol surfactants in soils amended with contaminated sewage sludges. In: Environmental chemistry: green chemistry and pollutants in ecosystems. Springer-Verlag, Berlin

    Google Scholar 

  • Efremov EV, Ariese F, Gooijer C (2008) Achievements in resonance Raman spectroscopy: review of a technique with a distinct analytical chemistry potential. Anal Chim Acta 606:119–134

    Article  CAS  PubMed  Google Scholar 

  • Eldridge HC, Milliken A, Farmer C et al (2017) Efficient remediation of 17 α-ethinylestradiol by Lentinula edodes (shiitake) laccase. Biocatal Agric Biotechnol 10:64–68

    Article  Google Scholar 

  • Ellis JB (2008) Assessing sources and impacts of priority PPCP compounds in urban receiving waters. In: 11th international conference on urban drainage, Edinburgh, Scotland, vol 1. pp 1–10

    Google Scholar 

  • Environmental Working Group (EWG) (2008) Almost half of all ‘natural’ personal care products contain known carcinogen. http://www.ewg.org/news/testimony-official-correspondence/study-almost-half-all-%E2%80% 98natural%E2%80%99-personal-care-products. Accessed 23 Mar 2016

  • Environmental Working Group (EWG) (2009) Hearing on the testing by the Department of Environmental Protection for the presence of pharmaceuticals and personal care products in the NYC drinking water supply. http://www.ewg.org/news/testimony-officialcorrespondence/testing-pharmaceuticalsand-personal-care-products-new-york. Accessed 23 Mar 2016

  • Ertit Tastan B, Donmez G (2015) Biodegradation of pesticide triclosan by A. versicolor in simulated wastewater and semi-synthetic media. Pestic Biochem Physiol 118:33–37

    Article  CAS  PubMed  Google Scholar 

  • Escapa C, Coimbra RN, Paniagua S et al (2017) Paracetamol and salicylic acid removal from contaminated water by microalgae. J Environ Manag 203:799–806

    Article  CAS  Google Scholar 

  • Escapa C, Torres T, Neuparth T et al (2018) Zebrafish embryo bioassays for a comprehensive evaluation of microalgae efficiency in the removal of diclofenac from water. Sci Total Environ 640–641:1024–1033

    Article  PubMed  CAS  Google Scholar 

  • Feng NX, Yu J, Zhao HM et al (2017) Efficient phytoremediation of organic contaminants in soils using plant–endophyte partnerships. Sci Total Environ 583:352–368

    Article  CAS  PubMed  Google Scholar 

  • Furgal KM, Meyer RL, Bester K (2014) Removing selected steroid hormones, biocides and pharmaceuticals from water by means of biogenic manganese oxide nanoparticles in situ at ppb levels. Chemosphere 136:321–326

    Article  PubMed  CAS  Google Scholar 

  • Galus M, Jeyaranjaan J, Smith E (2013a) Chronic effects of exposure to a pharmaceutical mixture and municipal wastewater in zebrafish. Aquat Toxicol 132–133:212–222

    Article  PubMed  CAS  Google Scholar 

  • Galus M, Kirischian N, Higgins S et al (2013b) Chronic, low concentration exposure to pharmaceuticals impacts multiple organ systems in zebrafish. Aquat Toxicol 132–133:200–211

    Article  PubMed  CAS  Google Scholar 

  • Gao T, Shi X (2018) Preparation of a synthetic seed for the common reed harboring an endophytic bacterium promoting seedling growth under cadmium stress. Environ Sci Pollut Res 25:8871–8879

    Article  CAS  Google Scholar 

  • Gao QT, Wong YS, Tam NFY (2017) Antioxidant responses of different microalgal species to nonylphenol-induced oxidative stress. J Appl Phycol 29:1317–1329

    Article  CAS  Google Scholar 

  • Garcia-Delgado C, Eymar E, Camacho-Arevalo R et al (2018) Degradation of tetracyclines and sulfonamides by stevensite- and biochar-immobilized laccase systems and impact on residual antibiotic activity. J Chem Technol Biotechnol 93:3394–3409

    Article  CAS  Google Scholar 

  • Garcia-Galan MJ, Gonzalez Blanco S, Lopez Roldan R et al (2012) Ecotoxicity evaluation and removal of sulfonamides and their acetylated metabolites during conventional wastewater treatment. Sci Total Environ 437:403–412

    Article  CAS  PubMed  Google Scholar 

  • Gauthier H, Yargeau V, Cooper DG (2010) Biodegradation of pharmaceuticals by Rhodococcus rhodochrous and Aspergillus niger by co-metabolism. Sci Total Environ 408:1701–1706

    Article  CAS  PubMed  Google Scholar 

  • Gilroy EAM, Balakrishnan VK, Solomon KR et al (2012) Behaviour of pharmaceuticals in spiked lake sediments-effects and interactions with benthic invertebrates. Chemosphere 86:578–584

    Article  CAS  PubMed  Google Scholar 

  • Gojkovic Z, Lindberg RH, Tysklind M, Funk C (2019) Northern green algae have the capacity to remove active pharmaceutical ingredients. Ecotoxicol Environ Saf 170:644–656

    Article  CAS  PubMed  Google Scholar 

  • Golveia JCS, Santiago MF, Sales PTF et al (2018) Cupuaçu (Theobroma grandiflorum) residue and its potential application in the bioremediation of 17-A-ethinylestradiol as a Pycnoporus sanguineus laccase inducer. Prep Biochem Biotechnol 48:541–548

    Article  CAS  PubMed  Google Scholar 

  • Gonda S, Kiss-Szikszai A, Szucs Z et al (2016) Efficient biotransformation of non-steroid anti-inflammatory drugs by endophytic and epiphytic fungi from dried leaves of a medicinal plant, Plantago lanceolata L. Int Biodeterior Biodegrad 108:115–121

    Article  CAS  Google Scholar 

  • Gonzalez-Benitez N, Molina MC, Arrayas M (2020) Empirical evidence and mathematical modelling of carbamazepine degradative kinetics by a wood-rotting microbial consortium. Waste Biomass Valori. https://doi.org/10.1007/s12649-020-01041-1

  • Gorny D, Guzik U, Hupert-Kocurek K, Wojcieszynska D (2019) A new pathway for naproxen utilisation by Bacillus thuringiensis B1 (2015b) and its decomposition in the presence of organic and inorganic contaminants. J Environ Manag 239:1–7

    Article  CAS  Google Scholar 

  • Gosset A, Durrieu C, Barbe P (2019) Microalgal whole-cell biomarkers as sensitive tools for fast toxicity and pollution monitoring of urban wet weather discharges. Chemosphere 217:522–533

    Article  CAS  PubMed  Google Scholar 

  • Grenni P, Patrolecco L, Ademollo N (2014) Capability of the natural microbial community in a river water ecosystem to degrade the drug naproxen. Environ Sci Pollut Res 21:13470–13479

    Article  CAS  Google Scholar 

  • Guo YP, Hu YY, Lin H, Ou XL (2018) Sorption and desorption of 17α-ethinylestradiol onto sediments affected by rhamnolipidic biosurfactants. J Hazard Mater 344:707–715

    Article  CAS  PubMed  Google Scholar 

  • Ha H, Mahanty B, Yoon S, Kim CG (2016) Degradation of the long-resistant pharmaceutical compounds carbamazepine and diatrizoate using mixed microbial culture. J Environ Sci Heal Part A Toxic/Hazardous Subst Environ Eng 51:467–471

    CAS  Google Scholar 

  • Hai FI, Modin O, Yamamoto K et al (2012) Pesticide removal by a mixed culture of bacteria and white-rot fungi. J Taiwan Inst Chem Eng 43:459–462

    Article  CAS  Google Scholar 

  • Hamjinda NS, Chiemchaisri W, Watanabe T et al (2018) Toxicological assessment of hospital wastewater in different treatment processes. Environ Sci Pollut Res 25:7271–7279

    Article  CAS  Google Scholar 

  • Heberer T (2002) Occurrence, fate, and removal of pharmaceutical residues in the aquatic environment: a review of recent research data. Toxicol Lett 131:5–17

    Article  CAS  PubMed  Google Scholar 

  • Hernando MD, Petrovic M, Fernandez-Alba AR, Barcelo D (2004) Analysis by liquid chromatography–electrospray ionization tandem mass spectrometry and acute toxicity evaluation for β-blockers and lipid-regulating agents in wastewater samples. J Chromatogr A 1046:133–140

    CAS  PubMed  Google Scholar 

  • Hernando MD, Mezcua M, Fernandez-Alba AR, Barcel D (2006) Environmental risk assessment of pharmaceutical residues in wastewater effluents, surface waters and sediments. Talanta 69:334–342

    Article  CAS  PubMed  Google Scholar 

  • Hignite C, Azarnoff DL (1977) Drugs and drug metabolites as environmental contaminants: chlorophenoxyisobutyrate and salicylic acid in sewage water effluent. Life Sci 20:337–341

    Article  CAS  PubMed  Google Scholar 

  • Huang W, Zhang Y, Zhang Y et al (2016) Optimization of the measurement of particle-bound reactive oxygen species with 2′,7′-dichlorofluorescin (DCFH). Water Air Soil Pollut 227:1–10

    Article  CAS  Google Scholar 

  • Huang B, Lai C, Dai H et al (2019a) Microbially reduced humic acid promotes the anaerobic photodegradation of 17α-ethinylestradiol. Ecotoxicol Environ Saf 171:313–320

    Article  CAS  PubMed  Google Scholar 

  • Huang Y, Guo J, Yan P et al (2019b) Sorption-desorption behavior of sulfamethoxazole, carbamazepine, bisphenol A and 17A-ethinylestradiol in sewage sludge. J Hazard Mater 368:739–745

    Article  CAS  PubMed  Google Scholar 

  • Huddleston J, Rogers R (1998) Room temperature ionic liquids as novel media for ‘clean’liquideliquid extraction. Chem Commun 16:1765–1766

    Article  Google Scholar 

  • Hultberg M, Prade T, Bodin H et al (2018) Adding benefit to wetlands – valorization of harvested common reed through mushroom production. Sci Total Environ 637:1395–1399

    Article  PubMed  CAS  Google Scholar 

  • Hurtado C, Dominguez C, Perez-Babace L et al (2016) Estimate of uptake and translocation of emerging organic contaminants from irrigation water concentration in lettuce grown under controlled conditions. J Hazard Mater 305:139–148

    Article  CAS  PubMed  Google Scholar 

  • Hussain J, Muhammad Z, Ullah R et al (2011) Biotransformation of ß-estradiol isolated from Sonchus eruca. African J Biotechnol 10:5529–5533

    CAS  Google Scholar 

  • Irwin LK, Gray S, Oberdorster E (2001) Vitellogenin induction in painted turtle, Chrysemys picta, as a biomarker of exposure to environmental levels of estradiol. Aquat Toxicol 55:49–60

    Article  CAS  PubMed  Google Scholar 

  • Isidori M, Lavorgna M, Nardelli A et al (2005) Ecotoxicity of naproxen and its phototransformation products. Sci Total Environ 348:93–101

    Article  CAS  PubMed  Google Scholar 

  • Janicki T, Krupinski M, Długonski J (2016) Degradation and toxicity reduction of the endocrine disruptors nonylphenol, 4-tert-octylphenol and 4-cumylphenol by the non-ligninolytic fungus Umbelopsis isabellina. Bioresour Technol 200:223–229

    Article  CAS  PubMed  Google Scholar 

  • Janicki T, Długonski J, Krupinski M (2018) Detoxification and simultaneous removal of phenolic xenobiotics and heavy metals with endocrine-disrupting activity by the non-ligninolytic fungus Umbelopsis isabellina. J Hazard Mater 360:661–669

    Article  CAS  PubMed  Google Scholar 

  • Jiang JQ, Zhou Z, Sharma VK (2013) Occurrence, transportation, monitoring and treatment of emerging micro-pollutants in waste water - a review from global views. Microchem J 110:292–300

    Article  CAS  Google Scholar 

  • Kang SI, Kang SY, Kanaly RA et al (2009) Rapid oxidation of ring methyl groups is the primary mechanism of biotransformation of gemfibrozil by the fungus Cunninghamella elegans. Arch Microbiol 191:509–517

    Article  CAS  PubMed  Google Scholar 

  • Kastner M, Nowak KM, Miltner A (2014) Classification and modelling of nonextractable residue (NER) formation of xenobiotics in soilea synthesis. Crit Rev Environ Sci Technol 44:2107–2171

    Article  CAS  Google Scholar 

  • Kemper N (2008) Veterinary antibiotics in the aquatic and terrestrial environment. Ecol Indic 8:1–13

    Article  CAS  Google Scholar 

  • Khanal SK, Xie B, Thompson ML, Sung S, Ong S-K, van Leeuwen J (2006) Fate, transport, and biodegradation of natural estrogens in the environment and engineered systems. Environ Sci Technol 40:6537–6546

    Article  CAS  PubMed  Google Scholar 

  • Khunjar WO, Mackintosh SA, Baik S et al (2011) Elucidating the relative roles of ammonia oxidizing and heterotrophic bacteria during the biotransformation of 17alpha-ethinylestradiol and trimethoprim. Environ Sci Technol 45:3605–3612

    Article  CAS  PubMed  Google Scholar 

  • Kim YM, Murugesan K, Schmidt S et al (2011) Triclosan susceptibility and co-metabolism - a comparison for three aerobic pollutant-degrading bacteria. Bioresour Technol 102:2206–2212

    Article  CAS  PubMed  Google Scholar 

  • Kinney CA, Furlong ET, Kolpin DW et al (2008) Bioaccumulation of pharmaceuticals and other anthropogenic waste indicators in earthworms from agricultural soil amended with biosolid or swine manure. Environ Sci Technol 42:1863–1870

    Article  CAS  PubMed  Google Scholar 

  • Kjeldal H, Zhou NA, Wissenbach DK et al (2016) Genomic, proteomic, and metabolite characterization of gemfibrozil-degrading organism Bacillus sp. GeD10. Environ Sci Technol 50:744–755

    Article  CAS  PubMed  Google Scholar 

  • Klampfl CW (2019) Metabolization of pharmaceuticals by plants after uptake from water and soil: a review. TrAC Trends Anal Chem 111:13–26

    Article  CAS  Google Scholar 

  • Kostich MS, Batt AL, Lazorchak JM (2014) Concentrations of prioritized pharmaceuticals in effluents from 50 large wastewater treatment plants in the US and implications for risk estimation. Environ Pollut 184:354–359

    Article  CAS  PubMed  Google Scholar 

  • Kouki S, Saidi N, M’hiri F et al (2016) Co-composting of macrophyte biomass and sludge as an alternative for sustainable management of constructed wetland by-products. Clean Soil Air Water 44:694–702

    Article  CAS  Google Scholar 

  • Kumari R, Ghosh Sachan S (2019) Bioconversion of toxic micropollutant triclosan to 2,4-dichlorophenol using a wastewater isolate Pseudomonas aeruginosa KS2002. Int J Environ Sci Technol 16:7663–7672

    Article  CAS  Google Scholar 

  • Kummerer K (2009) The presence of pharmaceuticals in the environment due to human use–present knowledge and future challenges. J Environ Manag 90:2354–2366

    Article  CAS  Google Scholar 

  • Kuzikova I, Safronova V, Zaytseva T, Medvedeva N (2017) Fate and effects of nonylphenol in the filamentous fungus Penicillium expansum isolated from the bottom sediments of the Gulf of Finland. J Mar Syst 171:111–119

    Article  Google Scholar 

  • La Farre M, Perez S, Kantiani L, Barcelo D (2008) Fate and toxicity of emerging pollutants, their metabolites and transformation products in the aquatic environment. TrAC Trends Anal Chem 27:991–1007

    Article  CAS  Google Scholar 

  • Lapworth D, Baran N, Stuart M, Ward R (2012) Emerging organic contaminants in groundwater: a review of sources, fate and occurrence. Environ Pollut 163:287–303

    Article  CAS  PubMed  Google Scholar 

  • Leng L, Wei L, Xiong Q et al (2020) Use of microalgae based technology for the removal of antibiotics from wastewater: a review. Chemosphere 238:124680

    Article  CAS  PubMed  Google Scholar 

  • Li H, Sumarah MW, Topp E (2013) Persistence of the tricyclic antidepressant drugs amitriptyline and nortriptyline in agriculture soils. Environ Toxicol Chem 32:509–516

    Article  CAS  PubMed  Google Scholar 

  • Li X, Xu QM, Cheng JS, Yuan YJ (2016) Improving the bioremoval of sulfamethoxazole and alleviating cytotoxicity of its biotransformation by laccase producing system under coculture of Pycnoporus sanguineus and Alcaligenes faecalis. Bioresour Technol 220:333–340

    Article  CAS  PubMed  Google Scholar 

  • Liu J-L, Wong M-H (2013) Pharmaceuticals and personal care products (PPCPs): a review on environmental contamination in China. Environ Int 59:208–224

    Article  CAS  PubMed  Google Scholar 

  • Liu S, Ying G-G, Zhao J-L et al (2011) Trace analysis of 28 steroids in surface water, wastewater and sludge samples by rapid resolution liquid chromatography–electrospray ionization tandem mass spectrometry. J Chromatogr A 1218:1367–1378

    Article  CAS  PubMed  Google Scholar 

  • Liu Q, Li M, Liu X et al (2018) Removal of sulfamethoxazole and trimethoprim from reclaimed water and the biodegradation mechanism. Front Environ Sci Eng 12:6

    Article  CAS  Google Scholar 

  • Lloret L, Eibes G, Lu-Chau TA (2010) Laccase-catalyzed degradation of anti-inflammatories and estrogens. Biochem Eng J 51:124–131

    Article  CAS  Google Scholar 

  • Lloret L, Eibes G, Feijoo G et al (2012) Degradation of estrogens by laccase from Myceliophthora thermophila in fed-batch and enzymatic membrane reactors. J Hazard Mater 213:175–183

    Article  PubMed  CAS  Google Scholar 

  • Loffredo E, Castellana G, Taskin E (2016) A two-step approach to eliminate pesticides and estrogens from a wastewater and reduce its phytotoxicity: adsorption onto plant-derived materials and fungal degradation. Water Air Soil Pollut 227:188

    Article  CAS  Google Scholar 

  • Lopez-Serna R, Posadas E, Garcia-Encina PA, Munoz R (2019) Removal of contaminants of emerging concern from urban wastewater in novel algal-bacterial photobioreactors. Sci Total Environ 662:32–40

    Article  CAS  PubMed  Google Scholar 

  • Loraine GA, Pettigrove ME (2006) Seasonal variations in concentrations of pharmaceuticals and personal care products in drinking water and reclaimed wastewater in southern California. Environ Sci Technol 40:687–695

    Article  CAS  PubMed  Google Scholar 

  • Lord H, Pawliszyn J (2000) Evolution of solid-phase microextraction technology. J Chromatogr A 885:153–193

    Article  CAS  PubMed  Google Scholar 

  • Lozano-Garcia DF, Cuellar-Bermudez SP, del Rio-Hinojosa E et al (2019) Potential land microalgae cultivation in Mexico: from food production to biofuels. Algal Res 39:101459

    Article  Google Scholar 

  • Lucas D, Castellet-Rovira F, Villagrasa M et al (2018) The role of sorption processes in the removal of pharmaceuticals by fungal treatment of wastewater. Sci Total Environ 610–611:1147–1153

    Article  PubMed  CAS  Google Scholar 

  • Ma Y, Oliveira RS, Freitas H, Zhang C (2016) Biochemical and molecular mechanisms of plant-microbe-metal interactions: relevance for phytoremediation. Front Plant Sci 7:753

    Article  Google Scholar 

  • Macci C, Peruzzi E, Doni S et al (2015) Ornamental plants for micropollutant removal in wetland systems. Environ Sci Pollut Res 22:2406–2415

    Article  CAS  Google Scholar 

  • Madukasi EI, Dai X, He C, Zhou J (2010) Potentials of phototrophic bacteria in treating pharmaceutical wastewater. Int J Environ Sci Technol 7:165–174

    Article  CAS  Google Scholar 

  • Maes HM, Maletz SX, Ratte HT et al (2014) Uptake, elimination, and biotransformation of 17 α-ethinylestradiol by the freshwater alga Desmodesmus subspicatus. Environ Sci Technol 48:12354–12361

    Article  CAS  PubMed  Google Scholar 

  • Mahmoud IS, Altaif KI, Sini MKA et al (2020) Determination of antimicrobial drug resistance among bacterial isolates in two hospitals of Baghdad. Jordan J Pharm Sci 13:1–9

    Google Scholar 

  • Mallick I, Bhattacharyya C, Mukherji S et al (2018) Effective rhizoinoculation and biofilm formation by arsenic immobilizing halophilic plant growth promoting bacteria (PGPB) isolated from mangrove rhizosphere: a step towards arsenic rhizoremediation. Sci Total Environ 610:1239–1250

    Article  PubMed  CAS  Google Scholar 

  • Marchlewicz A, Domaradzka D, Guzik U, Wojcieszyńska D (2016) Bacillus thuringiensis B1 (2015b) is a gram-positive bacteria able to degrade naproxen and ibuprofen. Water Air Soil Pollut 227:1–8

    Article  CAS  Google Scholar 

  • Margot J, Bennati-Granier C, Maillard J et al (2013) Bacterial versus fungal laccase: potential for micropollutant degradation. AMB Express 3:63

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Maryskova M, Ardao I, Garcia-Gonzalez CA et al (2016) Polyamide 6/chitosan nanofibers as support for the immobilization of Trametes versicolor laccase for the elimination of endocrine disrupting chemicals. Enzym Microb Technol 89:31–38

    Article  CAS  Google Scholar 

  • Matamoros V, Uggetti E, Garcia J, Bayona JM (2016) Assessment of the mechanisms involved in the removal of emerging contaminants by microalgae from wastewater: a laboratory scale study. J Hazard Mater 301:197–205

    Article  CAS  PubMed  Google Scholar 

  • McClellan K, Halden RU (2010) Pharmaceuticals and personal care products in archived U.S. biosolids from the 2001 EPA national sewage sludge survey. Water Res 44:658–668

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Merugu R, Prashanthi Y, Sarojini T, Badgu N (2014) Bioremediation of waste waters by the anoxygenic photosynthetic bacterium Rhodobacter sphaeroides SMR 009. Int J Res Environ Sci Technol 4:16–19

    Google Scholar 

  • Mikeskova H, Novotny C, Svobodova K (2012) Interspecific interactions in mixed microbial cultures in a biodegradation perspective. Appl Microbiol Biotechnol 95:861–870

    Article  CAS  PubMed  Google Scholar 

  • Mohammadhosseini M, Tehrani MS, Ganjali MR (2006) Preconcentration, determination and speciation of chromium (III) using solid phase extraction and flame atomic absorption spectrometry. J Chin Chem Soc 53:549–557

    Article  CAS  Google Scholar 

  • Molina MC, Bautista LF, Belda I et al (2019) Bioremediation of soil contaminated with arsenic. In: Ashok K, Swati S (eds) Microbes and enzymes in soil health and bioremediation. Springer, Singapore, pp 321–351

    Chapter  Google Scholar 

  • Molina MC, Bautista LF, Catala M et al (2020) From laboratory tests to the ecoremedial system: the importance of microorganisms in the recovery of PPCPs-disturbed ecosystems. Appl Sci 10:3391

    Article  CAS  Google Scholar 

  • Mompelat S, Le Bot B, Thomas O (2009) Occurrence and fate of pharmaceutical products and by-products, from resource to drinking water. Environ Int 35:803–814

    Article  CAS  PubMed  Google Scholar 

  • Moon DS, Song HG (2012) Degradation of alkylphenols by white rot fungus Irpex lacteus and its manganese peroxidase. Appl Biochem Biotechnol 168:542–549

    Article  CAS  PubMed  Google Scholar 

  • Munz NA, Burdon FJ, de Zwart D et al (2017) Pesticides drive risk of micropollutants in wastewater impacted streams during low flow conditions. Water Res 110:366–377

    Article  CAS  PubMed  Google Scholar 

  • Munze R, Hannemann C, Orlinskiy P et al (2017) Pesticides from wastewater treatment plant effluents affect invertebrate communities. Sci Total Environ 599-600:387–399

    Article  PubMed  CAS  Google Scholar 

  • Murdoch RW, Hay AG (2013) Genetic and chemical characterization of ibuprofen degradation by Sphingomonas Ibu-2. Microbiology 159:621–632

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Murugesan K, Bokare V, Jeon JR et al (2011) Effect of Fe-Pd bimetallic nanoparticles on Sphingomonas sp. PH-07 and a nano-bio hybrid process for triclosan degradation. Bioresour Technol 102:6019–6025

    Article  CAS  PubMed  Google Scholar 

  • Navrozidou E, Melidis P, Ntougias S (2019) Biodegradation aspects of ibuprofen and identification of ibuprofen-degrading microbiota in an immobilized cell bioreactor. Environ Sci Pollut Res 26:14238–14249

    Article  CAS  Google Scholar 

  • Nguyen LN, Van de Merwe JP, Hai FI et al (2016) Laccase-syringaldehyde-mediated degradation of trace organic contaminants in an enzymatic membrane reactor: removal efficiency and effluent toxicity. Bioresour Technol 200:477–484

    Article  CAS  PubMed  Google Scholar 

  • Nguyen PM, Afzal M, Ullah I et al (2019a) Removal of pharmaceuticals and personal care products using constructed wetlands: effective plant-bacteria synergism may enhance degradation efficiency. Environ Sci Pollut Res 26:21109–21126

    Article  Google Scholar 

  • Nguyen PY, Silva AF, Reis AC et al (2019b) Bioaugmentation of membrane bioreactor with Achromobacter denitrificans strain PR1 for enhanced sulfamethoxazole removal in wastewater. Sci Total Environ 648:44–55

    Article  CAS  PubMed  Google Scholar 

  • Nikolaou A, Meric S, Fatta D (2007) Occurrence patterns of pharmaceuticals in water and wastewater environments. Anal Bioanal Chem 387:1225–1234

    Article  CAS  PubMed  Google Scholar 

  • Norvill ZN, Shilton A, Guieysse B (2016) Emerging contaminant degradation and removal in algal wastewater treatment ponds: identifying the research gaps. J Hazard Mater 313:291–309

    Article  CAS  PubMed  Google Scholar 

  • Oaks JL, Gilbert M, Virani MZ et al (2004) Diclofenac residues as the cause of vulture population decline in Pakistan. Nature 427:630–633

    Article  CAS  PubMed  Google Scholar 

  • Olicon-Hernandez DR, González-Lopez J, Aranda E (2017) Overview on the biochemical potential of filamentous fungi to degrade pharmaceutical compounds. Front Microbiol 8:1–7

    Article  Google Scholar 

  • Olicon-Hernandez DR, Camacho-Morales RL, Pozo C et al (2019) Evaluation of diclofenac biodegradation by the ascomycete fungus Penicillium oxalicum at flask and bench bioreactor scales. Sci Total Environ 662:607–614

    Article  CAS  PubMed  Google Scholar 

  • Ootsuka M, Nishizawa T, Hasegawa M et al (2018) Comparative analysis of the genetic basis of branched nonylphenol degradation by Sphingobium amiense DSM 16289 T and Sphingobium cloacae JCM 10874 T. Microbes Environ 33:450–454

    Article  PubMed  PubMed Central  Google Scholar 

  • Otto B, Beuchel C, Liers C et al (2015) Laccase-like enzyme activities from chlorophycean green algae with potential for bioconversion of phenolic pollutants. FEMS Microbiol Lett 362:fnv072

    Article  PubMed  CAS  Google Scholar 

  • Overturf MD, Anderson JC, Pandelides Z et al (2015) Pharmaceuticals and personal care products: a critical review of the impacts on fish reproduction. Crit Rev Toxicol 45:469–491

    Article  CAS  PubMed  Google Scholar 

  • Pai PV, Pai A, Pai S et al (2013) Effect of glucose and nitrogen source on caffeine degradation by four filamentous fungi. Indian J Biotechnol 12:432–434

    CAS  Google Scholar 

  • Painter MM, Buerkley MA, Julius ML et al (2009) Antidepressants at environmentally relevant concentrations affect predator avoidance behavior of larval fathead minnows (Pimephales promelas). Environ Toxicol Chem 28:2677–2684

    Article  CAS  PubMed  Google Scholar 

  • Parshikov IA, Muraleedharan KM, Avery MA, Williamson JS (2004) Transformation of artemisinin by Cunninghamella elegans. Appl Microbiol Biotechnol 64:782–786

    Article  CAS  PubMed  Google Scholar 

  • Pauwels B, Wille K, Noppe H et al (2008) 17 α-ethinylestradiol cometabolism by bacteria degrading estrone, 17β-estradiol and estriol. Biodegradation 19:683–693

    Article  CAS  PubMed  Google Scholar 

  • Pedersen JA, Soliman M, Suffet IH (2005) Human pharmaceuticals, hormones, and personal care product ingredients in runoff from agricultural fields irrigated with treated wastewater. J Agric Food Chem 53:1625–1632

    Article  CAS  PubMed  Google Scholar 

  • Petryna A, Kleinman A, Lakoff A (2006) The pharmaceutical nexus. In: Global pharmaceuticals: ethics, markets, practices. Duke University Press, Durham, pp 1–32

    Google Scholar 

  • Popa C, Favier L, Dinica R et al (2014) Potential of newly isolated wild Streptomyces strains as agents for the biodegradation of a recalcitrant pharmaceutical, carbamazepine. Environ Technol (U K) 35:3082–3091

    Article  CAS  Google Scholar 

  • Prenosilova L, Kresinova Z, Amemori AS et al (2013) Transcriptional response of lignin-degrading enzymes to 17 α-ethinyloestradiol in two white rots. Microb Biotechnol 6:300–306

    Article  CAS  PubMed  Google Scholar 

  • Pruden A, Pei R, Storteboom H, Carlson KH (2006) Antibiotic resistance genes as emerging contaminants: studies in northern Colorado. Environ Sci Technol 40:7445–7450

    Article  CAS  PubMed  Google Scholar 

  • Puyol D, Batstone DJ, Hulsen T et al (2017) Resource recovery from wastewater by biological technologies: opportunities, challenges, and prospects. Front Microbiol 7:1–23

    Article  Google Scholar 

  • Quandt EM, Summers RM, Subramanian MV, Barrick JE (2015) Draft genome sequence of the bacterium Pseudomonas putida CBB5, which can utilize caffeine as a sole carbon and nitrogen source. Genome Announc 3:5–6

    Article  Google Scholar 

  • Rajapaksha AU, Vithanage M, Lim JE et al (2014) Invasive plant-derived biochar inhibits sulfamethazine uptake by lettuce in soil. Chemosphere 111:500–504

    Article  CAS  PubMed  Google Scholar 

  • Rajapaksha AU, Vithanage M, Ahmad M et al (2015) Enhanced sulfamethazine removal by steam-activated invasive plant-derived biochar. J Hazard Mater 290:43–50

    Article  CAS  PubMed  Google Scholar 

  • Reis PJM, Reis AC, Ricken B et al (2014) Biodegradation of sulfamethoxazole and other sulfonamides by Achromobacter denitrificans PR1. J Hazard Mater 280:741–749

    Article  CAS  PubMed  Google Scholar 

  • Reis AC, Cvancarova M, Liu Y et al (2018) Biodegradation of sulfamethoxazole by a bacterial consortium of Achromobacter denitrificans PR1 and Leucobacter sp. GP. Appl Microbiol Biotechnol 102:10299–10314

    Article  CAS  PubMed  Google Scholar 

  • Richardson ML, Bowron JM (1985) The fate of pharmaceutical chemicals in the aquatic environment. J Pharm Pharmacol 37:1–12

    Article  CAS  PubMed  Google Scholar 

  • Rodarte-Morales AI, Feijoo G, Moreira MT, Lema JM (2012) Biotransformation of three pharmaceutical active compounds by the fungus Phanerochaete chrysosporium in a fed batch stirred reactor under air and oxygen supply. Biodegradation 23:145–156

    Article  CAS  PubMed  Google Scholar 

  • Rodriguez E, Ruiz-Duenas FJ, Kooistra R et al (2008) Isolation of two laccase genes from the white-rot fungus Pleurotus eryngii and heterologous expression of the pel3 encoded protein. J Biotechnol 134:9–19

    Article  CAS  PubMed  Google Scholar 

  • Roh H, Subramanya N, Zhao F et al (2009) Biodegradation potential of wastewater micropollutants by ammonia-oxidizing bacteria. Chemosphere 77:1084–1089

    Article  CAS  PubMed  Google Scholar 

  • Rovani S, Censi MT, Pedrotti SL et al (2014) Development of a new adsorbent from agro-industrial waste and its potential use in endocrine disruptor compound removal. J Hazard Mater 344:350–359

    Google Scholar 

  • Salamanca EJP, Madera-Parra CA, Avila-Williams CA et al (2015) Phytoremediation using terrestrial plants. In: Phytoremediation. Springer, Berlin, pp 305–319

    Chapter  Google Scholar 

  • Sanchez-Galvan G, Bolanos-Santiago Y (2018) Phytofiltration of anaerobically digested sugarcane ethanol stillage using a macrophyte with high potential for biofuel production. Int J Phytoremediation 20:805–812

    Article  CAS  PubMed  Google Scholar 

  • Sarmah AK, Halling-Sørensen B (2007) Biodegradation of selected emerging organic contaminants in the environment-an overview. In: Pawley LE (ed) Leading-edge environmental biogradation research. Nova Science Publishers, Hauppauge, NY

    Google Scholar 

  • Sauvetre A, Schroder P (2015) Uptake of carbamazepine by rhizomes and endophytic bacteria of Phragmites australis. Front Plant Sci 6:1–11

    Google Scholar 

  • Sauvetre A, May R, Harpaintner R et al (2018) Metabolism of carbamazepine in plant roots and endophytic rhizobacteria isolated from Phragmites australis. J Hazard Mater 342:85–95

    Article  CAS  PubMed  Google Scholar 

  • Scudellari M (2015) Humans have spiked ecosystems with a flood of active pharmaceuticals. The drugs are feminizing male fish, confusing birds, and worrying scientists. The Scientist (Magazine)

    Google Scholar 

  • Shan L, Li Y, Chen Y et al (2016) Microbial hydroxylation of 17β-estradiol by Penicillium brevicompactum. Biocatal Biotransformation 34:137–143

    Article  CAS  Google Scholar 

  • Shi JH, Suzuki Y, Lee BD, Nakai S, Hosomi M (2002) Isolation and characterization of the ethynylestradiol-biodegrading microorganism Fusarium proliferatum strain HNS-1. Water Sci Technol 45:175–179

    Article  CAS  PubMed  Google Scholar 

  • Shi W, Wang L, Rousseau DPL, Lens PNL (2010) Removal of estrone, 17α-ethinylestradiol, and 17ß-estradiol in algae and duckweed-based wastewater treatment systems. Environ Sci Pollut Res 17:824–833

    Article  CAS  Google Scholar 

  • Shrestha P, Oh TJ, Liou K, Sohng JK (2008) Cytochrome P450 (CYP105F2) from Streptomyces peucetius and its activity with oleandomycin. Appl Microbiol Biotechnol 79:555–562

    Article  CAS  PubMed  Google Scholar 

  • Singh P, Singh VK, Singh R et al (2020) Bioremediation: a sustainable approach for management of environmental contaminants. In: Abatement of environmental pollutants. Elsevier, Amsterdam, pp 1–23

    Google Scholar 

  • Sopajarn A, Sangwichien C (2015) Optimization of enzymatic saccharification of alkali pretreated Typha angustifolia for glucose production. Int J Chem Eng Appl 6:232–236

    CAS  Google Scholar 

  • Stahl E (1967) Thin-layer chromatography. A laboratory handbook, 2nd edn. Springer, Berlin

    Google Scholar 

  • Swan Gerry E, Cuthbert R, Quevedo M et al (2006) Toxicity of diclofenac to Gyps vultures. Biol Lett 2:279–282

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Tabata A, Kashiwada S, Ohnishi Y et al (2001) Estrogenic influences of estradiol-17b, pnonylphenol and bis-phenol-A on Japanese Medaka (Oryzias latipes) at detected environmental concentrations. Water Sci Technol 43:109–116

    Article  CAS  PubMed  Google Scholar 

  • Taggart MA, Cuthbert R, Das D (2007) Diclofenac disposition in Indian cow and goat with reference to Gyps vulture population declines. Environ Pollut 147:60–65

    Article  CAS  PubMed  Google Scholar 

  • Tanoue R, Sato Y, Motoyama M et al (2012) Plant uptake of pharmaceutical chemicals detected in recycled organic manure and reclaimed wastewater. J Agric Food Chem 60:10203–10211

    Article  CAS  PubMed  Google Scholar 

  • Tastan BE, Ozdemir C, Tekinay T (2016) Effects of different culture media on biodegradation of triclosan by Rhodotorula mucilaginosa and Penicillium sp. Water Sci Technol 74:473–481

    Article  CAS  Google Scholar 

  • Taylor D, Senac T (2014) Human pharmaceutical products in the environment–the “problem” in perspective. Chemosphere 115:95–99

    Article  CAS  PubMed  Google Scholar 

  • Ternes TA, Herrmann N, Bonerz M et al (2004) A rapid method to measure the solid–water distribution coefficient (Kd) for pharmaceuticals and musk fragrances in sewage sludge. Water Res 38:4075–4084

    Article  CAS  PubMed  Google Scholar 

  • Thelusmond JR, Strathmann TJ, Cupples AM (2016) The identification of carbamazepine biodegrading phylotypes and phylotypes sensitive to carbamazepine exposure in two soil microbial communities. Sci Total Environ 571:1241–1252

    Article  CAS  PubMed  Google Scholar 

  • Thelusmond JR, Strathmann TJ, Cupples AM (2019) Carbamazepine, triclocarban and triclosan biodegradation and the phylotypes and functional genes associated with xenobiotic degradation in four agricultural soils. Sci Total Environ 657:1138–1149

    Article  CAS  PubMed  Google Scholar 

  • Thurman EM, Mills MS (1998) Solid-phase extraction: principles and practice, vol 16. Wiley, New York

    Google Scholar 

  • Tian H, Ma YJ, Li WY, Wang JW (2018) Efficient degradation of triclosan by an endophytic fungus Penicillium oxalicum B4. Environ Sci Pollut Res 25:8963–8975

    Article  CAS  Google Scholar 

  • Tortella G, Duran N, Rubilar O (2015) Are white-rot fungi a real biotechnological option for the improvement of environmental health? Crit Rev Biotechnol 35:165–172

    Article  CAS  PubMed  Google Scholar 

  • Toyama T, Murashita M, Kobayashi K et al (2011) Acceleration of nonylphenol and 4-tert-octylphenol degradation in sediment by phragmites australis and associated rhizosphere bacteria. Environ Sci Technol 45:6524–6530

    Article  CAS  PubMed  Google Scholar 

  • Toyama T, Ojima T, Tanaka Y et al (2013) Sustainable biodegradation of phenolic endocrine-disrupting chemicals by Phragmites australis-rhizosphere bacteria association. Water Sci Technol 68:522–529

    Article  CAS  PubMed  Google Scholar 

  • Tran TN, Kim DG, Ko SO (2018) Synergistic effects of biogenic manganese oxide and Mn(II)-oxidizing bacterium Pseudomonas putida strain MnB1 on the degradation of 17 A-ethinylestradiol. J Hazard Mater 344:350–359

    Article  CAS  PubMed  Google Scholar 

  • Trautwein C, Berset JD, Wolschke H, Kummerer K (2014) Occurrence of the antidiabetic drug metformin and its ultimate transformation product guanylurea in several compartments of the aquatic cycle. Environ Int 70:203–212

    Article  CAS  PubMed  Google Scholar 

  • Treesubsuntorn C, Thiravetyan P (2018) Botanical biofilter for indoor toluene removal and reduction of carbon dioxide emission under low light intensity by using mixed C3 and CAM plants. J Clean Prod 194:94–100

    Article  CAS  Google Scholar 

  • Treesubsuntorn C, Dolphen R, Dhurakit P et al (2017) Green technology innovation in a developing country. AIP Conf Proc 1908:030004. https://doi.org/10.1063/1.5012704

    Article  Google Scholar 

  • Vasiliadou IA, Sanchez-Vazquez R, Molina R et al (2016) Biological removal of pharmaceutical compounds using white-rot fungi with concomitant FAME production of the residual biomass. J Environ Manag 180:228–237

    Article  CAS  Google Scholar 

  • Vasiliadou IA, Molina R, Pariente MI et al (2019) Understanding the role of mediators in the efficiency of advanced oxidation processes using white-rot fungi. Chem Eng J 359:1427–1435

    Article  CAS  Google Scholar 

  • Vithanage M, Rajapaksha AU, Tang X et al (2014) Sorption and transport of sulfamethazine in agricultural soils amended with invasive-plant-derived biochar. J Environ Manag 141:95–103

    Article  CAS  Google Scholar 

  • Vo HNP, Ngo HH, Guo W et al (2020) Microalgae for saline wastewater treatment: a critical review. Crit Rev Environ Sci Technol 50:1224–1265

    Article  CAS  Google Scholar 

  • Wang J, Wang S (2016) Removal of pharmaceuticals and personal care products (PPCPs) from wastewater: a review. J Environ Manag 182:620–640

    Article  CAS  Google Scholar 

  • Wang D, Sui Q, Lu SG et al (2014) Occurrence and removal of six pharmaceuticals and personal care products in a wastewater treatment plant employing anaerobic/anoxic/aerobic and UV processes in Shanghai, China. Environ Sci Pollut Res 21:4276–4285

    Article  CAS  Google Scholar 

  • Wang Z, Dai Y, Zhao Q et al (2015) Nonylphenol biodegradation, functional gene abundance and bacterial community in bioaugmented sediment: effect of external carbon source. Environ Sci Pollut Res 22:12083–12091

    Article  CAS  Google Scholar 

  • Wang L, Peng Y, Nie X et al (2016) Gene response of CYP360A, CYP314, and GST and whole-organism changes in Daphnia magna exposed to ibuprofen comparative biochemistry and physiology. Comp Biochem Physiol C Toxicol Pharmacol 179:49–56

    Article  CAS  PubMed  Google Scholar 

  • Wang S, Hu Y, Wang J (2018a) Biodegradation of typical pharmaceutical compounds by a novel strain Acinetobacter sp. J Environ Manag 217:240–246

    Article  CAS  Google Scholar 

  • Wang S, Poon K, Cai Z (2018b) Removal and metabolism of triclosan by three different microalgal species in aquatic environment. J Hazard Mater 342:643–650

    Article  CAS  PubMed  Google Scholar 

  • Wang P, Zheng D, Peng W (2019) Characterization of 17β-hydroxysteroid dehydrogenase and regulators involved in estrogen degradation in Pseudomonas putida SJTE-1. Appl Microbiol Biotechnol 103:2413–2425

    Article  CAS  PubMed  Google Scholar 

  • Watahiki S, Kimura N (2017) Draft genome sequence of a caffeine-utilizing bacterium, Cupriavidus sp. strain D384. Genome Announc 5:e00370–e00317

    Article  PubMed  PubMed Central  Google Scholar 

  • Weigel S, Berger U, Jensen E et al (2004) Determination of selected pharmaceuticals and caffeine in sewage and seawater from Tromso/Norway with emphasis on ibuprofen and its metabolites. Chemosphere 56:583–592

    Article  CAS  PubMed  Google Scholar 

  • Wilson CJ, Brain RA, Sanderson H et al (2004) Structural and functional responses of plankton to a mixture of four tetracyclines in aquatic microcosms. Environ Sci Technol 38:6430–6439

    Article  CAS  PubMed  Google Scholar 

  • Wojcieszynska D, Domaradzka D, Hupert-Kocurek K, Guzik U (2014) Bacterial degradation of naproxen - undisclosed pollutant in the environment. J Environ Manag 145:157–161

    Article  CAS  Google Scholar 

  • Woo HL, Hazen TC, Simmons BA, DeAngelis KM (2014) Enzyme activities of aerobic lignocellulolytic bacteria isolated from wet tropical forest soils. Syst Appl Microbiol 37:60–67

    Article  CAS  PubMed  Google Scholar 

  • Wu X, Ernst F, Conkle JL, Gan J (2013) Comparative uptake and translocation of pharmaceutical and personal care products (PPCPs) by common vegetables. Environ Int 60:15–22

    Article  CAS  PubMed  Google Scholar 

  • Xiong JQ, Kurade MB, Abou-Shanab RAI et al (2016) Biodegradation of carbamazepine using freshwater microalgae Chlamydomonas mexicana and Scenedesmus obliquus and the determination of its metabolic fate. Bioresour Technol 205:183–190

    Article  CAS  PubMed  Google Scholar 

  • Xiong JQ, Kurade MB, Jeon BH (2018) Can microalgae remove pharmaceutical contaminants from water? Trends Biotechnol 36:30–44

    Article  CAS  PubMed  Google Scholar 

  • Xiong JQ, Govindwar S, Kurade MB et al (2019a) Toxicity of sulfamethazine and sulfamethoxazole and their removal by a green microalga, Scenedesmus obliquus. Chemosphere 218:551–558

    Article  CAS  PubMed  Google Scholar 

  • Xiong JQ, Kim SJ, Kurade MB et al (2019b) Combined effects of sulfamethazine and sulfamethoxazole on a freshwater microalga, Scenedesmus obliquus: toxicity, biodegradation, and metabolic fate. J Hazard Mater 370:138–146

    Article  CAS  PubMed  Google Scholar 

  • Yang S, Hai FI, Nghiem LD et al (2013) Understanding the factors controlling the removal of trace organic contaminants by white-rot fungi and their lignin modifying enzymes: a critical review. Bioresour Technol 359:203–212

    Google Scholar 

  • Yang Y, Ok YS, Kim KH et al (2017) Occurrences and removal of pharmaceuticals and personal care products (PPCPs) in drinking water and water/sewage treatment plants: a review. Sci Total Environ 596:303–320

    Article  PubMed  CAS  Google Scholar 

  • Yang Z, Shi Y, Zhang Y et al (2018) Different pathways for 4-n-nonylphenol biodegradation by two Aspergillus strains derived from estuary sediment: evidence from metabolites determination and key-gene identification. J Hazard Mater 359:203–212

    Article  CAS  PubMed  Google Scholar 

  • Zha J, Sun L, Zhou Y et al (2008) Assessment of 17α-ethinylestradiol effects and underlying mechanisms in a continuous, multigeneration exposure of the Chinese rare minnow (Gobiocypris rarus). Toxicol Appl Pharmacol 226:298–308

    Article  CAS  PubMed  Google Scholar 

  • Zhang D, Luo J, Lee ZMP et al (2016) Characterization of microbial communities in wetland mesocosms receiving caffeine-enriched wastewater. Environ Sci Pollut Res 23:14526–14539

    Article  CAS  Google Scholar 

  • Zhang H, Wang L, Li Y et al (2019a) Background nutrients and bacterial community evolution determine 13 C-17β-estradiol mineralization in lake sediment microcosms. Sci Total Environ 651:2304–2311

    Article  CAS  PubMed  Google Scholar 

  • Zhang Z, Ruan Z, Liu J et al (2019b) Complete degradation of bisphenol A and nonylphenol by a composite of biogenic manganese oxides and Escherichia coli cells with surface-displayed multicopper oxidase CotA. Chem Eng J 362:897–908

    Article  CAS  Google Scholar 

  • Zheng G, Wang T, Niu M et al (2018) Biodegradation of nonylphenol during aerobic composting of sewage sludge under two intermittent aeration treatments in a full-scale plant. Environ Pollut 238:783–791

    Article  CAS  PubMed  Google Scholar 

  • Zhong DF, Sun L, Liu L, Huang HH (2003) Microbial transformation of naproxen by Cunninghamella species. Acta Pharmacol Sin 24:442–447

    CAS  PubMed  Google Scholar 

  • Zhou NA, Lutovsky AC, Andaker GL et al (2014) Kinetics modeling predicts bioaugmentation with Sphingomonad cultures as a viable technology for enhanced pharmaceutical and personal care products removal during wastewater treatment. Bioresour Technol 166:158–167

    Article  CAS  PubMed  Google Scholar 

  • Zhou B, Ma C, Wang H, Xia T (2018) Biodegradation of caffeine by whole cells of tea-derived fungi Aspergillus sydowii, Aspergillus niger and optimization for caffeine degradation. BMC Microbiol 18:1–10

    Article  CAS  Google Scholar 

Download references

Author information

Author notes

  1. Mahendar Porika and Pabbati Ranjit contributed equally with all other contributors.

Authors and Affiliations

  1. Department of Biotechnology, Kakatiya University, Warangal, Telangana, India

    Mahendar Porika & Radhika Tippani

  2. Centre for Biotechnology, Institute of Science & Technology, Jawaharlal Nehru Technological University, Hyderabad, Telangana, India

    Pabbati Ranjit & Kondakindi Venkateswar Reddy

Authors
  1. Mahendar Porika
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Pabbati Ranjit
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Radhika Tippani
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Kondakindi Venkateswar Reddy
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Environmental Microbiology, Babasaheb Bhimrao Ambedkar University, Lucknow, Uttar Pradesh, India

    Pankaj Kumar Arora

Rights and permissions

Reprints and permissions

Copyright information

© 2021 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Porika, M., Ranjit, P., Tippani, R., Reddy, K.V. (2021). Advances in the Bioremediation of Pharmaceuticals and Personal Care Products (PPCPs): Polluted Water and Soil. In: Arora, P.K. (eds) Microbial Products for Health, Environment and Agriculture . Microorganisms for Sustainability, vol 31. Springer, Singapore. https://doi.org/10.1007/978-981-16-1947-2_15

Download citation

Publish with us

Policies and ethics

Search

Navigation