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Potential of Nano-Structured Drug Delivery System for Phytomedicine Delivery

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Nanophytomedicine

Abstract

Based on the problems associated with the delivery of herbal medicines, various investigations have been carried out. The field of formulation and development appeared progressive when we see the reports published in the previous few decades. Recent advancements in this field are based on the necessities of improved solubility, release, biological absorption, targetability, safety, dosing schedule, stability, efficacy, and patient compliance along with the decreased dose and dose-dependent side effects. Formulation scientists are now interested in the exploitation of new drug delivery system (NDDS) to deliver phytomedicine at the required rate for the entire treatment period and to channelize the phytomolecules at the desired site of action. These systems are meant to meet the unmet medical conditions that cannot be met using conventional dosage forms. Nanocarriers such as nanoparticles, nanocapsules, lipid carriers, solid lipid nanoparticles, phytosomes, nanoemulsion, and many more have shown an array of advantages while delivering phytomolecules to the site of action. Due to the proven advantages over conventional dosage forms, nano-phytomedicines have immense potential in the improvement of deliverability of the isolated and established herbal molecules. This chapter, however, includes various aspects of justification for the immense potential of the nano-structured drug delivery system for phytomedicine delivery and future prospects. In addition, the area of nanostructured carrier systems in the potential delivery of phytomedicine, and the nano-phytomedicines which have been prepared for improved solubility, pharmacokinetic profile (ADME), bioavailability, targetability, efficacy, and safety are also highlighted in this chapter.

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Authors and Affiliations

  1. Department of Pharmaceutics, ISF College of Pharmacy, Moga, Punjab, India

    Vineet Kumar Rai & Ghanshyam Das Gupta

  2. Department of Pharmacology, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia

    Faheem Hyder Pottoo

  3. Department of Pharmaceutics, College of Pharmacy, University of Hafr Al-Batin, Hafr Al-Batin, Saudi Arabia

    Md. Abul Barkat

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  1. Vineet Kumar Rai
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  2. Ghanshyam Das Gupta
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  3. Faheem Hyder Pottoo
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  4. Md. Abul Barkat
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Editors and Affiliations

  1. Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, Delhi, India

    Sarwar Beg

  2. Department of Pharmaceutics, College of Pharmacy, University of Hafr Al-Batin, Hafr Al-Batin, Saudi Arabia

    Md Abul Barkat

  3. Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, Delhi, India

    Farhan Jalees Ahmad

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Rai, V.K., Gupta, G.D., Pottoo, F.H., Barkat, M.A. (2020). Potential of Nano-Structured Drug Delivery System for Phytomedicine Delivery. In: Beg, S., Barkat, M., Ahmad, F. (eds) Nanophytomedicine. Springer, Singapore. https://doi.org/10.1007/978-981-15-4909-0_6

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