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Routes of Exposures and Toxicity of Nanoparticles

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Model Organisms to Study Biological Activities and Toxicity of Nanoparticles

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Abstract

Nanotechnology is a vast growing research niche and has found its application in diverse fields. The vast applications include the environment, chemical, biological, electronics, medicine, and sports. The miniature size and high surface area of nanoparticles (NPs) do cause increased toxicological effects on various organisms. To know the effects of NPs exposure, the current chapter presents the various routes of exposures and its toxicity on different model systems. Different NPs can pass through the host system via the skin, olfactory route, respiratory tract, and oral route. The entry of these NPs in the following routes may be either during their production, use, intentional, or unintentional. The entry of NPs in the following routes may lead to negative biological effects. The key points for discussion in this chapter include the routes of exposure of different NPs and their toxicology impact at that particular point of entry and the target organ.

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Acknowledgments

The author is thankful to FCT for research funding to Srikanth K (SFRH/BPD/79490/2011) and to the University of Aveiro Research Institute (CESAM).

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Authors and Affiliations

  1. CESAM-Centre for Environment & Marine Studies and Department of Chemistry, University of Aveiro, Aveiro, Portugal

    Koigoora Srikanth

  2. Department of Biotechnology, VIGNAN’S Foundation for Science Technology & Research, Deemed to be University, Vadlamudi, Andhra Pradesh, India

    Koigoora Srikanth

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  1. Koigoora Srikanth
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Correspondence to Koigoora Srikanth .

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Editors and Affiliations

  1. Department of Microbiology, School of Life Sciences, Pondicherry University, Pondicherry, India

    Busi Siddhardha

  2. Department of Biochemistry and Molecular Biology, School of Life Sciences, Pondicherry University, Pondicherry, India

    Madhu Dyavaiah

  3. Materials Research Group, iThemba LABS-National Research Fond., Cape Town, South Africa

    Kaviyarasu Kasinathan

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Srikanth, K. (2020). Routes of Exposures and Toxicity of Nanoparticles. In: Siddhardha, B., Dyavaiah, M., Kasinathan, K. (eds) Model Organisms to Study Biological Activities and Toxicity of Nanoparticles. Springer, Singapore. https://doi.org/10.1007/978-981-15-1702-0_13

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