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Alginate-Based Interpenetrating Network Carriers for Biomedical Applications

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Interpenetrating Polymer Network: Biomedical Applications

Abstract

With advances in modern medicine, there has been a constant need to develop a single material that caters to all demands such as high tensile strength, biocompatibility and biodegradability. The development of an interpenetrating polymer network (IPN) is both an outstanding innovation and contribution that has led to massive technological advances across a wide spectrum of applications in medicine. IPNs comprising natural and synthetic polymers are typically endowed with improved properties compared to monolithic materials and offer superior properties. Most importantly, synergism of properties has also been observed in most of the systems. This chapter discusses the potential of alginate-based IPN carriers for biomedical applications.

Alginate is a naturally occurring anionic polysaccharide widely employed in a broad spectrum of biomedical applications. The ability to assemble alginate with a diversity of polymers and to fabricate IPNs makes it a promising choice for various applications in biomedicine. This chapter discusses at length the various inherent properties of alginate that make it suitable as a biomaterial. The state-of-art applications of alginate IPNs in drug delivery, wound healing and tissue engineering have also been elaborated. The prospective of alginate in delivery of small molecule drugs as well as protein drugs has been presented. This chapter further focuses on the potential of alginate IPNs in wound dressings and regenerative medicine.

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  1. Department of Chemistry, Ravenshaw University, Cuttack, Odisha, India

    Subhraseema Das

  2. Department of Chemistry, NIT Rourkela, Rourkela, Odisha, India

    Usharani Subuddhi

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  1. Department of Pharmaceutics, Gupta College of Technological Sciences, Asansol, West Bengal, India, Department of Health and Family Welfare, Directorate of Health Services, Kolkata, India

    Sougata Jana

  2. Department of Chemistry, Indira Gandhi National Tribal University, Amarkantak, Madhya Pradesh, India

    Subrata Jana

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Das, S., Subuddhi, U. (2020). Alginate-Based Interpenetrating Network Carriers for Biomedical Applications. In: Jana, S., Jana, S. (eds) Interpenetrating Polymer Network: Biomedical Applications. Springer, Singapore. https://doi.org/10.1007/978-981-15-0283-5_4

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