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Strain Improvement for Industrial Production of Lignocellulolytic Enzyme by Talaromyces cellulolyticus

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Fungal Cellulolytic Enzymes

Abstract

Talaromyces cellulolyticus (formerly known as Acremonium cellulolyticus) is a commercial fungal source used for industrial enzyme production for silage preparation. In this chapter, the development of T. cellulolyticus strains to produce lignocellulolytic enzymes suitable for the hydrolysis of target biomass is reviewed. High-yield production and composition improvements of lignocellulolytic enzymes in T. cellulolyticus have been succeeded by mutagenesis, genetic engineering, and enzyme preparation up to the present date. Recent developments of T. cellulolyticus genetic tools including whole genome sequencing, homologous recombination, marker recycling, RNA interference, genome editingĀ and transcriptional regulation, a concept of core and accessary enzymes, and their utilization for strain improvements will be discussed.

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Fujii, T., Inoue, H., Yano, S., Sawayama, S. (2018). Strain Improvement for Industrial Production of Lignocellulolytic Enzyme by Talaromyces cellulolyticus . In: Fang, X., Qu, Y. (eds) Fungal Cellulolytic Enzymes. Springer, Singapore. https://doi.org/10.1007/978-981-13-0749-2_7

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