Skip to main content

Pathologies Segmentation in Eye Fundus Images Based on Frequency Domain Filters

  • Conference paper
  • First Online:
Transactions on Engineering Technologies (WCECS 2015)

Abstract

This chapter presents a novel method based on discrete frequency transforms to segment various pathologies in eye fundus color images such as exudates, blood vessels, and aneurysms. Non-uniform illuminated eye fundus images are corrected by applying a homomorphic high-pass frequency filter. Then, a super-Gaussian band-pass filter defined in the frequency transform domain is used to distinguish between background and foreground objects. The filtering step works with the green channel that usually contains the most relevant information to segment different pathologies. Specifically, exudates detection after transform inversion of the filtered image requires a gamma correction to enhance foreground objects. Otsu’s thresholding method is applied to the enhanced image and masked over the effective area to get the segmented exudates. For blood vessels and aneurysms, back in the spatial domain, the negative of the filtered image is required. Then a median filter is applied to reduce noise or artifacts followed by gamma contrast enhancement. Again, Otsu’s thresholding method is used for image binarization. Next a morphological closing operation is applied and masking the effective image area gives the segmented blood vessels or aneurysms. Illustrative examples using retinographies from a free public domain clinical database are included to demonstrate the capability of the frequency filter approach.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Netdoctor: Diabetic retinopathy (eye disease), 2016. http://www.netdoctor.co.uk/conditions/diabetes/a833/diabetic-retinopathy-eye-disease/

  2. Rowe S, MacLean CH, Shekelle PG (2004) Preventing visual loss from chronic eye disease in primary care: scientific review. J Am Med Assoc 291(12):1487–1495

    Article  Google Scholar 

  3. Chou R, Dana T, Bougatsos C (2009) Screening older adults for impaired visual acuity: a review of the evidence for the US preventive services task force. Ann Intern Med 151(1):44–58

    Google Scholar 

  4. Jaafar HF, Nandi AK, Al-Nuaimy W (2011) Detection of exudates from digital fundus images using a region-based segmentation technique. In: Proceedings of the IEEE, 19th European signal processing conference 2011, pp 1020–1024

    Google Scholar 

  5. Budai A, Bock R, Maier A, Hornegger J, Michelson G (2013) Robust vessel segmentation in fundus images. Int J Biomed Imaging:1–11

    Google Scholar 

  6. Garaibeh NY (2014) Automatic exudate detection using eyes fundus image analysis due to diabetic retinopathy. Comput Inf Sci 7(2):48

    Google Scholar 

  7. Welfer D, Scharcanski J, Marinho DR (2010) A coarse-to-fine strategy for automatically detecting exudates in color eye fundus images. Comput Med Imaging Graph 34(3):228–235

    Article  Google Scholar 

  8. Kaur J, Mittal D (2015) Segmentation and measurement of exudates in fundus images of the retina for detection of retinal disease. J Biomed Eng Med Imaging 2(1):27

    Google Scholar 

  9. Saleh MD, Eswaran C, Mueen A (2011) An automated blood vessel segmentation algorithm using histogram equalization and automatic threshold selection. J Digit Imaging 24(4):564–572

    Article  Google Scholar 

  10. Zana F, Klein J-C (1999) A multimodal registration algorithm of eye fundus images using vessels detection and Hough transform. IEEE Trans Med Imaging 18(5):419–428

    Article  Google Scholar 

  11. Walter T, Klein J-C (2002) Automatic detection of microaneurysms in color fundus images of the human retina by means of the bounding box closing. Med Data Anal Springer:210–220

    Google Scholar 

  12. Walter T, Klein J-C, Massin P, Erginay A (2002) A contribution of image processing to the diagnosis of diabetic retinopathy detection of exudates in color fundus images of the human retina. IEEE Trans Med Imaging 21(10):1236–1243

    Article  Google Scholar 

  13. Kauppi T, Kalesnykiene V, Kamarainen J-K, Lensu L, Sorri I, Raninen A, Voutilainen R, Uusitalo H, Kälviäinen H, Pietilä J (2007) The DIARETDB1 diabetic retinopathy database and evaluation protocol. In: Proceedings of the British machine vision conference, BMVA Press, pp 15.1–15.10

    Google Scholar 

  14. Jain AK (1979) A sinusoidal family of unitary transforms. IEEE Trans Pattern Anal Mach Intell PAMI-1(4):356–365

    Google Scholar 

  15. Pratt WK (2007) Digital image processing, 4th edn. PIKS scientific inside. Wiley, Los Altos, California

    Google Scholar 

  16. Gonzalez RC, Woods RE (2008) Digital image processing, 3rd edn. Pearson, Prentice -Hall, Upper Saddle River

    Google Scholar 

  17. Lara RLD, López ME, Urcid G (2015) Blood vessels and exudates segmentation in eye fundus images based on Fourier filtering. Lecture notes in engineering and computer science: proceedings of the world congress on engineering and computer science 2015, WCECS 2015, 21–23 Oct 2015, San Francisco, USA, pp 503–507

    Google Scholar 

  18. Parent A, Morin M, Lavigne P (1992) Propagation of super-Gaussian field distributions. Opt Quant Electron 24(9):S1071–S1079

    Article  Google Scholar 

  19. Otsu N (1979) A threshold selection method from gray-level histograms. IEEE Trans Syst Man Cybern 9(1):62–66

    Article  MathSciNet  Google Scholar 

  20. Dorland. Dorland’s illustrated medical dictionary. Dorland’s Medical Dictionary, Elsevier Health Sciences (2011)

    Google Scholar 

  21. Lappeenranta University: Standard Diabetic Retinopathy Database, 2011. http://www.it.lut.fi/project/imageret/diaretdb0/

  22. Fawcett T (2006) An introduction to ROC analysis. Pat Rec Lett 27(8):861–874

    Article  MathSciNet  Google Scholar 

  23. Kande GB, Subbaiah PV, Savithri TS (2008) Segmentation of exudates and optic disk in retinal images. In: 6th Indian conference on computational visual, graphics and imaging proceedings 2008, pp 535–542

    Google Scholar 

  24. Niemeijer M, Staal J, van Ginneken B, Loog M, Abramoff MD (2004) Comparative study of retinal vessel segmentation methods on a new publicly available database. Med Imaging International Society for Optics and Photonics:648–656

    Google Scholar 

  25. Rangayyan RM, Ayres FJ, Oloumi F, Oloumi F, Eshghzadeh-Zanjani P (2008) Detection of blood vessels in the retina with multiscale Gabor filters. J Electr. Image 17(2):023018

    Article  Google Scholar 

  26. Staal J, Abràmoff MD, Niemeijer M, Viergever M, Van Ginneken B et al (2004) Ridge-based vessel segmentation in color images of the retina. IEEE Trans Med Imaging 23(4):501–509

    Article  Google Scholar 

Download references

Acknowledgements

Gonzalo Urcid thanks the National Research System (SNI-CONACYT) for partial financial support through grant No. 22036. Luis David Lara-Rodríguez and Elizabeth López-Meléndez are grateful with the National Council of Science and Technology (CONACYT) for doctoral scholarships CVU-332238 and CVU-332355, respectively.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Gonzalo Urcid .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer Nature Singapore Pte Ltd.

About this paper

Cite this paper

Urcid, G., Lara-R, L.D., López-M, E. (2017). Pathologies Segmentation in Eye Fundus Images Based on Frequency Domain Filters. In: Ao, SI., Kim, H., Amouzegar, M. (eds) Transactions on Engineering Technologies. WCECS 2015. Springer, Singapore. https://doi.org/10.1007/978-981-10-2717-8_10

Download citation

  • DOI: https://doi.org/10.1007/978-981-10-2717-8_10

  • Published:

  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-10-2716-1

  • Online ISBN: 978-981-10-2717-8

  • eBook Packages: EngineeringEngineering (R0)

Publish with us

Policies and ethics