Skip to main content
SpringerLink
Log in

Cell death in biology and pathology

  • Book
  • © 1981

Overview

Editors:
  1. I. D. Bowen

    1. Department of Zoology, University College, Cardiff, UK

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. R. A. Lockshin

    1. Department of Biological Sciences, St John’s University, New York, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (14 chapters)

  1. Front Matter

    Pages i-xviii
    Download chapter PDF

  2. Introduction

    • I. D. Bowen, R. A. Lockshin
    Pages 1-7

  3. Cell death: a new classification separating apoptosis from necrosis

    • A. H. Wyllie
    Pages 9-34

  4. Cell death in embryogenesis

    • J. R. Hinchliffe
    Pages 35-78

  5. Cell death in metamorphosis

    • Richard A. Lockshin
    Pages 79-121

  6. Tissue homeostasis and cell death

    • S. M. Hinsull, D. Bellamy
    Pages 123-144

  7. Cell senescence and death in plants

    • P. B. Gahan
    Pages 145-169

  8. The tissue kinetics of cell loss

    • N. A. Wright
    Pages 171-207

  9. Cell death and the disease process. The role of calcium

    • Benjamin F. Trump, Irene K. Berezesky, Alvaro R. Osornio-Vargas
    Pages 209-242

  10. Cell death in vitro

    • Leonard Hayflick
    Pages 243-285

  11. Nucleic acids in cell death

    • Richard A. Lockshin, Moira Royston, Michael Joesten, Timothy Carter
    Pages 287-293

  12. Mechanism(s) of action of nerve growth factor in intact and lethally injured sympathetic nerve cell in neonatal rodents

    • Rita Levi-Montalcini, Luigi Aloe
    Pages 295-327

  13. Glucocorticoid-induced lymphocyte death

    • Allan Munck, Gerald R. Crabtree
    Pages 329-359

  14. The role of the LT system in cell destruction in vitro

    • Monica W. Ross, Robert S. Yamamoto, Gale A. Granger
    Pages 361-377

  15. Techniques for demonstrating cell death

    • I. D. Bowen
    Pages 379-444

  16. Back Matter

    Pages 445-493
    Download chapter PDF
Back to top

Keywords

About this book

It is clear that lysosomal enzymes often play a role in the destruction of the cytoplasm, but very few authorities feel that they initiate the process (Chapters 1, 2, 3, 5 -8, 12, 13). The cells show many forms of damage, and sometimes even complete destruction, before Iysosomes become a dominant part of the environ­ ment. What initiates the process is still unclear, although in several instances it appears that the death of a cell may arise from anyone of several pathways (Chapters, 10, II). It is rather interesting that evolution has chosen to achieve the same goal by different means. Apparently no one point is exceptionally or pre­ ferentially vulnerable, though a common pathway, such as permeability of the plasma membrane to calcium (Chapter 7), might currently be too subtle for routine identification. Factors which affect membrane stability and which induce mem­ brane bending can lead to blebing, cell fragmentation and death. Thus, more work on the changing chemistry of the plasma membrane in relation to environmental fluctuations would be welcomed. Space requirements and the major orientation of the book forced the exclusion of several very interesting topics: an evolutionary treatment of the advantages of cell death as a means of eliminating vestigial organs or embryonic scaffolding; or consider­ ation of the merits of body sculpting by cell death rather than cell growth.

Editors and Affiliations

  • Department of Zoology, University College, Cardiff, UK

    I. D. Bowen

  • Department of Biological Sciences, St John’s University, New York, USA

    R. A. Lockshin

Bibliographic Information

  • Book Title: Cell death in biology and pathology

  • Editors: I. D. Bowen, R. A. Lockshin

  • DOI: https://doi.org/10.1007/978-94-011-6921-9

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: Chapman and Hall Ltd 1981

  • Softcover ISBN: 978-94-011-6923-3Published: 14 March 2012

  • eBook ISBN: 978-94-011-6921-9Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XVIII, 493

  • Topics: Science, Humanities and Social Sciences, multidisciplinary

Publish with us

Policies and ethics

Back to top

Search

Navigation