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Biochemistry and cell physiology of organ preservation

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Procurement, Preservation and Allocation of Vascularized Organs

Abstract

The enormous success of organ transplantation is due in part to the development of methods to preserve organs from the time they are donated until they are transplanted. Preservation has the goal of maintaining the viability of organs ex vivo for a period of time that will allow maximal utilization of all cadaveric organs. Over the past 25 years of organ transplantation it has become clear that most organs can be transported to an appropriate recipient within about 24 h after procurement. To give a margin of safety and to maximize utilization of all organs, ideal preservation times would be at least two to three times this clinical minimum (48–72 h).

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Authors
  1. James H. Southard
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Editor information

Editors and Affiliations

  1. Department of Transplantation, California Pacific Medical Center, San Francisco, California, USA

    G. M. Collins

  2. Transplantation Pavillon V, Hôpital Edouard Herriot, Lyon, France

    J. M. Dubernard

  3. Division of Transplant Surgery, Department of Surgery, Klinikum Grosshadern, University of Munich, Munich, Germany

    W. Land

  4. Eurotransplant Foundation, Leiden, The Netherlands

    G. G. Persijn

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© 1997 Springer Science+Business Media Dordrecht

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Southard, J.H. (1997). Biochemistry and cell physiology of organ preservation. In: Collins, G.M., Dubernard, J.M., Land, W., Persijn, G.G. (eds) Procurement, Preservation and Allocation of Vascularized Organs. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5422-2_12

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  • DOI: https://doi.org/10.1007/978-94-011-5422-2_12

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6280-0

  • Online ISBN: 978-94-011-5422-2

  • eBook Packages: Springer Book Archive

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