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Organization, regulation and function of Pseudomonas syringae pv. syringae hrp genes

  • Chapter
Molecular Mechanisms of Bacterial Virulence

Part of the book series: Developments in Plant Pathology ((DIPP,volume 3))

Abstract

The pathogenicity and host range of Pseudomonas syringae is controlled in part by hrp genes. Inactivation of these genes produces nonpathogenic mutants that are unable to elicit the hypersensitive response (HR) in resistant plants or nonhost plant species, a response indicative of incompatibility. In P.s. syringae 61, the hrp genes cluster in a 25 kb region of the genome. Transposon mutagenesis and complementation analyses in merodiploids have revealed 16 apparent translational units organized as seven apparent transcriptional units. Associated with the hrp cluster is the hrmA locus. Phenotypic expression of the hrplhrm gene cluster in non-phytopathogenic bacteria, such as E. coli, enables these bacteria to elicit the HR in a wide variety of plant species. TnphoA mutagenesis has identified two hrp genes that produce membrane-associated proteins. Eight of the hrp operons are regulated by nutritional conditions. At least two hrp loci have regulatory activity. Nucleotide sequence analysis of the region has revealed several loci sharing substantial homology with Yersinia virulence genes. The role of these genes in determining P. syringae pathogenicity and elicitation of the HR are discussed

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Abbreviations

HR:

Hypersensitive Response

hrp :

Hypersensitive Response-Pathogencity

hrm :

Hypersensitive Response Modulation

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Authors
  1. Steven W. Hutcheson
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  2. Sunggi Heu
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  3. Hsiou-Chen Huang
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  4. Michael C. Lidell
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  5. Yingxian Xiao
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Editor information

Editors and Affiliations

  1. University of California, Davis, CA, 95616, USA

    C. I. Kado

  2. Oregon Health Sciences University, Portland, OR, 97201, USA

    J. H. Crosa

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© 1994 Springer Science+Business Media Dordrecht

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Hutcheson, S.W., Heu, S., Huang, HC., Lidell, M.C., Xiao, Y. (1994). Organization, regulation and function of Pseudomonas syringae pv. syringae hrp genes. In: Kado, C.I., Crosa, J.H. (eds) Molecular Mechanisms of Bacterial Virulence. Developments in Plant Pathology, vol 3. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-0746-4_42

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  • DOI: https://doi.org/10.1007/978-94-011-0746-4_42

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-4322-9

  • Online ISBN: 978-94-011-0746-4

  • eBook Packages: Springer Book Archive

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