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Nanoparticles Enhanced Hyperthermia

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Intracellular Delivery

Part of the book series: Fundamental Biomedical Technologies ((FBMT,volume 5))

Abstract

Nano-hyperthermia is regarded as a promising alternative to conventional thermal ablation. Many nanoparticles with specific physical properties in electrical, magnetic, acoustic, optical or thermal features have been tried to induce various enhanced hyperthermia, aiming to significantly improve the treatment efficiency of conventional heating. This article is dedicated to present a comprehensive review on the thermal properties, targeted heating mechanisms, and heat generation beha­viors of typical nanoparticles. In addition, potential combination of the nanoparticles with radiotherapy and/or chemotherapy will also be discussed.

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Abbreviations

CNT:

Carbon nanotube

CVD:

Chemical vapor deposition

GNP:

Gold nanoparticle

HF:

High frequency

HIFU:

High intensity focused ultrasound

LF:

Low frequency

LITT:

Laser-induced thermotherapy

MF:

Middle frequency

MGC:

Magnetic glass-ceramic

MNP:

Magnetic nanoparticle

MRI:

Magnetic resonance imaging

MW:

Microwave

MWNT:

Multi-walled carbon nanotubes

NIR:

Near-infrared

PTT:

Photothermal therapy

PVA:

Polyvinyl alcohol

RF:

Radiofrequency

SAR:

Specific absorption rate

SPM:

Superparamagnetic

SWNT:

Single-walled carbon nanotube

UCA:

Ultrasound contrast agents

UHF:

Ultra high frequency

VHF:

Very high frequency

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Acknowledgment

This work is partially supported by the NSFC under grant No.81071255 and Tsinghua-Yue-Yuen Medical Sciences Fund.

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  1. Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, 100084, P. R. China

    Qian Wang & Jing Liu

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  1. Qian Wang
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  2. Jing Liu
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Correspondence to Jing Liu .

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  1. , Chemical and Biological Engineering, Vanderbilt University, VU Station B 351604, Nashville, 37235, Tennessee, USA

    Aleš Prokop

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Wang, Q., Liu, J. (2011). Nanoparticles Enhanced Hyperthermia. In: Prokop, A. (eds) Intracellular Delivery. Fundamental Biomedical Technologies, vol 5. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-1248-5_20

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