Abstract
Surface plasmon resonance represents a new tool for the simple, fast and cheap nucleic acid detection. Large efforts have been paid during the last decade with the aim to develop even more sensitive and specific SPR-based methods to be used for the direct detection of genomic DNA. This Chapter, after a description of fundamentals of surface plasmon resonance and allied techniques, will review the state-of-the-art of recent platform and assay developments and will provide an overview of recent uses of SPR techniques for the direct detection of non-amplified nucleic acids.
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Sassolas, A., Leca-Bouvier, B.D., Blum, L.J.: DNA biosensors and microarrays. Chem. Rev. 108, 109–139 (2008)
Alkan, C., Coe, B.P., Eichler, E.E.: Applications of next-generation sequencing genome structural variation discovery and genotyping. Nat. Rev. Gen. 12, 363–375 (2011)
Schaaf, C.P., Wiszniewska, J., Beaudet, A.L.: Copy number and SNP arrays in clinical diagnostics. Annu. Rev. Gen Hum. Genet. 12, 25–51 (2011)
Germini, A., Rossi, S., Zanetti, A., Corradini, R., Fogher, C., Marchelli, R.: Development of a PNA array platform for the detection of GMOs in food. J. Agric. Food Chem. 53, 3958–3962 (2005)
Roh, S.W., Abell, G.C.J., Kim, K.H., Nam, Y.D., Bae, J.W.: Comparing microarrays and next-generation sequencing technologies for microbial ecology research. Trends Biotechnol. 28, 291–299 (2011)
Gong, P., Levicky, R.: DNA surface hybridization regimes. Proc. Natl. Acad. Sci. USA 105, 5301–5306 (2008)
Homola, J.: Surface Plasmon Resonance Based Sensors. Springer Series on Chemical Sensors and Biosensors. Springer, Berlin/Heidelberg (2006)
Wood, R.W.: Diffraction gratings with controlled groove form and abnormal distribution of intensity. Philosophical Magazine Series 6 23, 310–317 (1912)
Schasfoort, R.B.M., Tudos, A.J.: Handbook of Surface Plasmon Resonance. The Royal Society of Chemistry, Cambridge (2008)
Born, M., Wolf, E.: Principle of Optics. Pergamon Press, Oxford (1980)
Raether, H.: Surface Plasmons on Smooth and Rough Surfaces and on Gratings. Springer, Berlin (1988)
Forstamann, F., Gerhardts, R.R: Metal Optics Near the Plasma Frequency, vol. 109 of Springer Tracts in Modern Physics. Springer, Berlin (1986)
Powell, C.J., Swan, J.B.: Effect of oxidation on the characteristic loss spectra of aluminum and magnesium. Phys. Rev. 118, 640–643 (1960)
Agranovich, V.M., Mills, D.L.: Surface Polaritons. North Holland Co., Amsterdam (1982)
Otto, A.: A new method for exciting nonradioactive surface plasma oscillations. Phys. Stat. Sol. 26, K99–K101 (1968)
Kretschmann, E., Reather, H.Z.: Radiative decay of non-radiative surface plasmons excited by light. Naturf. 23A, 2135–2136 (1968)
Matsubara, K., Rawata, S., Minami, S.: Multilayer system for a high-precision surface plasmon resonance sensor. Opt. Lett. 15, 75–77 (1990)
Akimoto, T., Sasaki, S., Ikebukuro, K., Karube, I.: Effect of incident angle of light on sensitivity and detection limit for layers of antibody with surface plasmon resonance spectroscopy. Biosens. Bioelectron. 15, 355–362 (2000)
Rich, R.L., Myszka, D.G.: Advances in surface plasmon resonance biosensor analysis. Curr. Opin. Biotechnol. 11, 54–61 (2000)
Piliarik, M., Vaisocherová, H., Homola, J.: Surface plasmon resonance biosensing. Meth. Mol. Biol. 503, 65–88 (2008)
Tumolo, T., Angnes, L., Baptista, M.S.: Determination of the refractive index increment (dn/dc) of molecule and macromolecule solutions by surface plasmon resonance. Anal. Biochem. 333, 273–279 (2004)
Lyon, L.A., Musick, M.D., Natan, M.J.: Colloidal Au-enhanced surface plasmon resonance immunosensing. Anal. Chem. 70, 5177–5183 (1998)
Frutos, A.G., Weibel, S.C., Corn, R.M.: Near-infrared surface plasmon resonance measurements of ultrathin films. 2. Fourier transform SPR spectroscopy. Anal. Chem. 71, 3935–3940 (1999)
Hickel, W., Kamp, D., Knoll, W.: Surface-plasmon microscopy. Nature 339, 186 (1989)
Grasso, G., D’Agata, R., Rizzarelli, E., Spoto, G., D’Andrea, L., Pedone, C., Picardi, A., Romanelli, A., Fragai, M., Yeo, K.J.: Activity of anchored human matrix metalloproteinase-12 catalytic domain on Au (111) surfaces monitored by ESI-MS. J. Mass Spectrom. 40, 1565–1571 (2005)
Grasso, G., Bush, A.I., D’Agata, R., Rizzarelli, E., Spoto, G.: Enzyme solid-state support assays: a surface plasmon resonance and mass spectrometry coupled study of immobilized insulin degrading enzyme. Eur. Biophys. J. 38, 407–414 (2009)
Chu, L.Q., Foerch, R., Knoll, W.: Surface-plasmon-enhanced fluorescence spectroscopy for DNA detection using fluorescently labeled PNA as “DNA indicator”. Angew. Chem. 119, 5032–5035 (2007)
Gifford, L.K., Sendroiu, I.E., Corn, R.M., Luptaka, A.: Attomole detection of mesophilic DNA polymerase products by nanoparticle-enhanced surface plasmon resonance imaging on glassified gold surfaces. J. Am. Chem. Soc. 132, 9265–9267 (2010)
Lockett, M.R., Weibel, S.C., Phillips, M.F., Shortreed, M.R., Sun, B., Corn, R.M., Hamers, R.J., Cerrina, F., Smith, L.M.: Carbon-on-metal films for surface plasmon resonance detection of DNA arrays. J. Am. Chem. Soc. 130, 8611–8613 (2008)
Zanoli, L.M., D’Agata, R., Spoto, G.: Functionalized gold nanoparticles for ultrasensitive DNA detection. Anal. Bioanal. Chem. 402, 1759–1771 (2012)
Lee, H.J., Wark, A.W., Corn, R.M.: Creating advanced multifunctional biosensors with surface enzymatic transformations. Langmuir 22, 5241–5250 (2006)
Phillips, K.S., Cheng, Q.: Recent advances in surface plasmon resonance based techniques for bioanalysis. Anal. Bioanal. Chem. 387, 1831–1840 (2007)
Attridge, J.W., Daniels, P.B., Deacon, J.K., Robinson, G.A., Davidson, G.P.: Sensitivity enhancement of optical immunosensors by the use of a surface plasmon resonance fluoroimmunoassay. Biosens. Bioelectron. 6, 201–214 (1991)
Schmidt, E.K., Liebermann, T., Kreiter, M., Jonczyk, A., Naumann, R., Offenhausser, A., Neumann, E., Kukol, A., Maelicke, A., Knoll, W.: Incorporation of the acetylcholine receptor dimer from Torpedo Californica in a peptide supported lipid membrane investigated by surface plasmon and fluorescence spectroscopy. Biosens. Bioelectron. 13, 585–591 (1998)
Neumann, T., Johansson, M., Kambhampati, D., Knoll, W.: Surface–plasmon fluorescence spectroscopy. Adv. Funct. Mater. 12, 575–586 (2002)
Dostálek, J., Knoll, W.: Biosensors based on surface plasmon-enhanced fluorescence spectroscopy. Biointerphases 3, FD12–FD22 (2008)
Ekgasit, S., Yu, F., Knoll, W.: Fluorescence intensity in surface-plasmon field-enhanced fluorescence spectroscopy. Sens. Actuators B 104, 294–301 (2005)
Liebermann, T., Knoll, W.: Surface-plasmon field-enhanced fluorescence spectroscopy. Colloids Surf. A 171, 115–130 (2000)
Kambhampati, D., Nielsen, P.E., Knoll, W.: Investigating the kinetics of DNA-DNA and PNA-DNA interactions using surface plasmon resonance-enhanced fluorescence spectroscopy. Biosens. Bioelectron. 16, 1109–1118 (2001)
Yao, D.F., Yu, F., Kim, J.Y., Scholz, J., Nielsen, P.E., Sinner, E.K., Knoll, W.: Surface plasmon field-enhanced fluorescence spectroscopy in PCR product analysis by peptide nucleic acid probes. Nucl. Acids Res. 32, 177–192 (2004)
Park, H., Germini, A., Sforza, S., Corradini, R., Marchelli, R., Knoll, W.: Kinetic and affinity analyses of hybridization reactions between peptide nucleic acid probes and DNA targets using surface plasmon field-enhanced fluorescence spectroscopy. Biointerphases 1, 113–122 (2006)
Rothenhäusler, B., Knoll, W.: Surface–plasmon microscopy. Nature 332, 615–617 (1988)
Smith, E.A., Corn, R.M.: Surface plasmon resonance imaging as a tool to monitor biomolecular interactions in an array based format. Appl. Spect. 57, 320–332 (2003)
Lee, H.J., Wark, A.W., Li, Y., Corn, R.M.: Fabricating RNA microarrays with RNA-DNA surface ligation chemistry. Anal. Chem. 77, 7832–7837 (2005)
Lee, H.J., Li, Y., Wark, A.W., Corn, R.M.: Enzymatically amplified surface plasmon resonance imaging detection of DNA by exonuclease III digestion of DNA microarrays. Anal. Chem. 77, 5096–5100 (2005)
Zhou, W.J., Chen, Y., Corn, R.M.: Ultrasensitive microarray detection of short RNA sequences with enzymatically modified nanoparticles and surface plasmon resonance imaging measurements. Anal. Chem. 83, 3897–3902 (2011)
Seefeld, T.H., Zhou, W.J., Corn, R.M.: Rapid microarray detection of DNA and proteins in microliter volumes with surface plasmon resonance imaging measurements. Langmuir 27, 6534–6540 (2011)
Kyo, M., Yamamoto, T., Motohashi, H., Kamiya, T., Kuroita, T., Tanaka, T., Engel, J.D., Kawakami, B., Yamamoto, M.: Evaluation of MafG interaction with Maf recognition element arrays by surface plasmon resonance imaging technique. Genes Cells 9, 153–164 (2004)
Li, Y., Lee, H.J., Corn, R.M.: Detection of protein biomarkers using RNA aptamer microarrays and enzymatically amplified SPR imaging. Anal. Chem. 79, 1082–1088 (2007)
Otsuki, S., Tamada, K., Wakida, S.: Wavelength-scanning surface plasmon resonance imaging. Appl. Opt. 44, 3468–3472 (2005)
Kim, M., Jung, S.O., Park, K., Jeong, E.J., Joung, H.A., Kim, T.H., Seol, D.W., Chung, B.H.: Detection of Bax protein conformational change using a surface plasmon resonance imaging-based antibody chip. Biochem. Biophys. Res. Commun. 338, 1834–1838 (2005)
Usui-Aoki, K., Shimada, K., Nagano, M., Kawai, M., Koga, H.: A novel approach to protein expression profiling using antibody microarrays combined with surface plasmon resonance technology. Proteomics 5, 2396–2401 (2005)
Lee, H.J., Wark, A.W., Goodrich, T.T., Fang, S., Corn, R.M.: Surface enzyme kinetics for biopolymer microarrays: a combination of Langmuir and Michaelis-Menten concepts. Langmuir 21, 4050–4057 (2005)
Wegner, G.J., Wark, A.W., Lee, H.J., Codner, E., Saeki, T., Fang, S., Corn, R.M.: Real-time surface plasmon resonance imaging measurements for the multiplexed determination of protein adsorption/desorption kinetics and surface enzymatic reactions on peptide microarrays. Anal. Chem. 76, 5677–5684 (2004)
(a) Yu, X., Xu, D., Cheng, Q.: Label-free detection methods for protein microarrays. Proteomics 6, 5493–5503 (2006); (b) Huang, H., Chen, Y.: Label-free reading of microarray-based proteins with high throughput surface plasmon resonance imaging. Biosens. Bioelect. 22, 644–648 (2006)
Huang, H., Chen, Y.: Label-free reading of microarray-based proteins with high throughput surface plasmon resonance imaging. Biosens. Bioelect. 22, 644–648 (2006)
Kanda, V., Kariuki, J.K., Harrison, D.J., McDermott, M.T.: Label-free reading of microarray-based immunoassays with surface plasmon resonance imaging. Anal. Chem. 76, 7257–7262 (2004)
Karamanska, R., Clarke, J., Blixt, O., MacRae, J.I., Zhang, J.Q., Crocker, P.R., Laurent, N., Wright, A., Flitsch, S.L., Russell, D.A., Field, R.A.: Surface plasmon resonance imaging for real-time, label-free analysis of protein interactions with carbohydrate microarrays. Glycoconj. J. 25, 69–74 (2008)
D’Agata, R., Grasso, G., Iacono, G., Spoto, G., Vecchio, G.: Lectin recognition of a new SOD mimic bioconjugate studied with surface plasmon resonance imaging. Org. Biomol. Chem. 4, 610–612 (2006)
Brockman, J.M., Nelson, B.P., Corn, R.M.: Surface plasmon resonance imaging measurements of ultrathin organic films. Annu. Rev. Phys. Chem. 51, 41–63 (2000)
Steiner, G.: Surface plasmon resonance imaging. Anal. Bioanal. Chem. 379, 328–331 (2004)
Shumaker-Parry, J.S., Campbell, C.T.: Quantitative methods for spatially-resolved adsorption/desorption measurements in real time by SPR microscopy. Anal. Chem. 76, 907–917 (2004)
Berger, C.E.H., Kooyman, R.P.H., Greve, J.: Resolution in surface plasmon microscopy. Rev. Sci. Instrum. 65, 2829–2836 (1994)
Yeatman, E.M.: Resolution and sensitivity in surface plasmon microscopy and sensing. Biosens. Bioelectron. 11, 635–649 (1996)
Squires, T.M., Quake, S.R.: Microfluidics: fluid physics at the nanoliter scale. Rev. Mod. Phys. 77, 977–1026 (2005)
D’Agata, R., Grasso, G., Spoto, G.: Real-time binding kinetics monitored with surface plasmon resonance imaging in a diffusion-free environment. Open Spectrosc. J. 2, 1–9 (2008)
Ouellet, E., Lausted, C., Lin, T., Wei, C., Yang, T., Hood, L., Lagally, E.T.: Parallel microfluidic surface plasmon resonance imaging arrays. Lab. Chip. 10, 581–588 (2010)
Grasso, G., D'Agata, R., Zanoli, L., Spoto, G.: Microfluidic networks for surface plasmon resonance imaging real-time kinetics experiments. Microchem. J. 93, 82–86 (2009)
Amarie, D., Alileche, A., Dragnea, B., Glazier, J.A.: Microfluidic devices integrating microcavity surface-plasmon-resonance sensors: glucose oxidase binding-activity detection. Anal. Chem. 82, 343–352 (2010)
Mannelli, I., Minunni, M., Tombelli, S., Wang, R., Spiriti, M.M., Mascini, M.: Direct immobilisation of DNA probes for the development of affinity biosensors. Bioelectrochemistry 66, 129–138 (2005)
Love, J.C., Estroff, L.A., Kriebel, J.K., Nuzzo, R.G., Whitesides, G.M.: Self-assembled monolayers of thiolates on metals as a form of nanotechnology. Chem. Rev. 105, 1103–1169 (2005)
Ladd, J., Taylor, A.D., Piliarik, M., Homola, J., Jiang, S.: Hybrid surface platform for the simultaneous detection of proteins and DNAs using a surface plasmon resonance imaging sensor. Anal. Chem. 80, 4231–4236 (2008)
Opdahl, A., Petrovykh, D.Y., Suda, H.K., Tarlov, M.J., Whitman, L.J.: Independent control of grafting density and conformation of single-stranded DNA brushes. Proc. Natl. Acad. Sci. USA 104, 9–14 (2007)
Gong, P., Lee, C.Y., Gamble, L.J., Castner, D.G., Grainger, D.W.: Hybridization behavior of mixed DNA/alkylthiol monolayers on gold: characterization by surface plasmon resonance and 32P radiometric assay. Anal. Chem. 78, 3326–3334 (2006)
Chen, Y., Nguyen, A., Niu, L., Corn, R.M.: Fabrication of DNA microarrays with poly(L-glutamic acid) monolayers on gold substrates for SPR imaging measurements. Langmuir 25, 5054–5060 (2009)
Ulman, A.: An Introduction to Ultrathin Organic Films: From Langmuir- Blodgett to Self-assembly. Academic, Boston (1991)
Knoll, W.: Interfaces and thin films as seen by bound electromagnetic waves. Annu. Rev. Phys. Chem. 49, 569–638 (1998)
Lockett, M.R., Smith, E.A.: Fabrication and characterization of DNA arrays prepared on carbon-on-metal substrates. Anal. Chem. 81, 6429–6437 (2009)
Touahir, L., Niedziolka-Jonsson, J., Galopin, E., Boukherroub, R., Gouget-Laemmel, A.C., Solomon, I., Petukhov, M., Chazalviel, J.N., Ozanam, F., Szunerits, S.: Surface plasmon resonance on gold and silver films coated with thin layers of amorphous silicon-carbon alloys. Langmuir 26, 6058–6065 (2010)
Singh-Gasson, S., Green, R.D., Yue, Y.J., Nelson, C., Blattner, F., Sussman, M.R., Cerrina, F.: Maskless fabrication of light-directed oligonucleotide microarrays using a digital micromirror array. Nat. Biotechnol. 17, 974–978 (1999)
Stewart, M.E., Anderton, C.R., Thompson, L.B., Maria, J., Gray, S.K., Rogers, J.A., Nuzzo, R.G.: Nanostructured plasmonic sensors. Chem. Rev. 108, 494–521 (2008)
Shalabney, A., Abdulhalim, I.: Sensitivity-enhancement methods for surface plasmon sensors. Laser Photonics Rev. 5, 571–606 (2011)
Malic, L., Cui, B., Veres, T., Tabrizian, M.: Enhanced surface plasmon resonance imaging detection of DNA hybridization on periodic gold nanoposts. Opt. Lett. 32, 3092–3094 (2007)
Byun, K.M., Shuler, M.L., Kim, S.J., Yoon, S.J., Kim, D.: Sensitivity enhancement of surface plasmon resonance imaging using periodic metallic nanowires. J. Lightwave Technol. 26, 1472–1478 (2008)
Hoa, X.D., Kirk, A.G., Tabrizian, M.: Enhanced SPR response from patterned immobilization of surface bioreceptors on nano-gratings. Biosens. Bioelectron. 24, 3043–3048 (2009)
Kim, K., Kim, D.J., Moon, S., Kim, D., Byun, K.M.: Localized surface plasmon resonance detection of layered biointeractions on metallic subwavelength nanogratings. Nanotech (2009). doi:10.1088/0957-4484/20/31/315501
Henzie, J., Lee, J., Lee, M.H., Hasan, W., Odom, T.W.: Nanofabrication of plasmonic structures. Annu. Rev. Phys. Chem. 60, 147–165 (2009)
Malic, L., Cui, B., Tabrizian, M., Veres, T.: Nanoimprinted plastic substrates for enhanced surface plasmon resonance imaging detection. Opt. Express 17, 20386–20392 (2009)
Piliarik, M., Homola, J.: Surface plasmon resonance (SPR) sensors: approaching their limits? Opt. Express 17, 16505–16517 (2009)
Nenninger, G.G., Tobiška, P., Homola, J., Yee, S.S.: Long-range surface plasmons for high-resolution surface plasmon resonance sensors. Sens. Actuators B 74, 145–151 (2001)
Wark, A.W., Lee, H.J., Corn, R.M.: Long-range surface plasmon resonance imaging for bioaffinity sensors. Anal. Chem. 77, 3904–3907 (2005)
Piliarik, M., Vaisocherova, H., Homola, J.: A new surface plasmon resonance sensor for high-throughput screening applications. Biosens. Bioelectron. 20, 2104–2110 (2005)
Piliarik, M., Vaisocherova, H., Homola, J.: Towards parallelized surface plasmon resonance sensor platform for sensitive detection of oligonucleotides. Sens. Actuat. B 121, 187–193 (2007)
Wark, A.W., Lee, H.J., Qavi, A.J., Corn, R.M.: Nanoparticle-enhanced diffraction gratings for ultrasensitive surface plasmon biosensing. Anal. Chem. 79, 6697–6701 (2007)
Sendroiu, I.E., Corn, R.M.: Nanoparticle diffraction gratings for DNA detection on photopatterned glass substrates. Biointerphases 3, FD23–FD29 (2008)
Halpern, A.R., Chen, Y., Corn, R.M., Kim, D.: Surface plasmon resonance phase imaging measurements of patterned monolayers and DNA adsorption onto microarrays. Anal. Chem. 83, 2801–2806 (2011)
Venter, J.C., Adams, M.D., Myers, E.W., Li, P.W., Mural, R.J., Sutton, G.G., Smith, H.O., Yandell, M., Evans, C.A., Holt, R.A., et al.: The sequence of the human genome. Science 291, 1304–1351 (2001)
Pennisi, E.: Human genome. Reaching their goal early, sequencing labs celebrate. Science 300, 409 (2003)
Gibson, G.: The environmental contribution to gene expression profiles. Nat. Rev. Genet. 9, 575–581 (2008)
Shi, L., Perkins, R.G., Fang, H., Tong, W.: Reproducible and reliable microarray results through quality control: good laboratory proficiency and appropriate data analysis practices are essential. Curr. Opin. Biotechnol. 19, 10–18 (2008)
Barnes, W.M.: PCR amplification of up to 35-kb DNA with high fidelity and high yield from lambda bacteriophage templates. Proc. Natl. Acad. Sci. USA 91, 2216–2220 (1994)
D’Aquila, R.T., Bechtel, L.J., Videler, J.A., Eron, J.J., Gorczyca, P., Kaplan, J.C.: Maximizing sensitivity and specificity of PCR by preamplification heating. Nucleic Acids Res. 19, 3749 (1991)
Sachidanandam, R.: A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms. Nature 409, 928–933 (2001)
Kruglyak, L.: The use of a genetic map of biallelic markers in linkage studies. Nat. Genet. 17, 21–24 (1997)
White, K.P.: Functional genomics and the study of development, variation and evolution. Nat. Rev. Genet. 2, 528–537 (2001)
Murray, S.S., Oliphant, A., Shen, R., McBride, C., Steeke, R.J., Shannon, S.G., Rubano, T., Kermani, B.G., Fan, J.B., Chee, M.S., Hansen, M.S.T.: A highly informative SNP linkage panel for human genetic studies. Nat. Methods 1, 113–117 (2004)
Lerman, L.S., Fisher, S.G., Hurley, I., Silverstein, K., Lumelsky, N.: Sequence-determined DNA separations. Annu. Rev. Biophys. 13, 399–433 (1984)
Minunni, M., Tombelli, S., Mascini, M.: A biosensor approach for DNA sequences detection in non-amplified genomic DNA. Anal. Lett. 40, 1360–1370 (2007)
Scarano, S., Mascini, M., Turner, A.P.F., Minunni, M.: Surface plasmon resonance imaging for affinity-based biosensors. Biosens. Bioelect. 25, 957–966 (2010)
Goodrich, T.T., Lee, H.J., Corn, R.M.: Direct detection of genomic DNA by enzymatically amplified SPR imaging measurements of RNA microarrays. J. Am. Chem. Soc. 126, 4086–4087 (2004)
He, L., Musick, M.D., Nicewarner, S.R., Salinas, F.G., Benkovic, S.J., Natan, M.J., Keating, C.D.: Colloidal Au-enhanced surface plasmon resonance for ultrasensitive detection of DNA hybridization. J. Am. Chem. Soc. 122, 9071–9077 (2000)
D’Agata, R., Corradini, R., Grasso, G., Marchelli, R., Spoto, G.: Ultrasensitive detection of DNA by PNA and nanoparticle-enhanced surface plasmon resonance imaging. Chembiochem 9, 2067–2070 (2008)
Mei, R., Hubbell, E., Bekiranov, S., Mittmann, M., Christians, R.C., Shen, M., Lu, G., Fang, J., Liu, W., Ryder, T., Kaplan, P., Kulp, D., Webster, T.A.: Probe selection for high-density oligonucleotide arrays. Proc. Natl. Acad. Sci. USA 100, 11237–11242 (2003)
Ermini, M.L., Scarano, S., Bini, R., Banchelli, M., Berti, D., Mascini, M., Minunni, M.: A rational approach in probe design for nucleic acid-based biosensing. Biosens. Bioelectron. 26, 4785–4790 (2011)
Chen, W.Y., Hu, W.P., Su, Y.D., Taylor, A., Jiang, S., Chang, G.L.: A multispot DNA chip fabricated with mixed ssDNA/oligo (ethylene glycol) self-assembled monolayers for detecting the effect of secondary structures on hybridization by SPR imaging. Sens. Actuat. B 125, 607–614 (2007)
Egholm, M., Buchardt, O., Christensen, L., Behrens, C., Freier, S.M., Driver, D.A., Berg, R.H., Kim, S.K., Norden, B., Nielsen, P.E.: PNA hybridizes to complementary oligonucleotides obeying the Watson–Crick hydrogen-bonding rules. Nature 365, 566–568 (1993)
Nielsen, P.E.: A brief review of some possible applications of PNAs. Curr. Opin. Biotechnol. 10, 71–75 (1999)
Zanoli, L., D’Agata, R., Spoto, G.: Surface plasmon-based optical detection of DNA by peptide nucleic acids. Minerva Biotec. 20, 165–174 (2008)
D’Agata, R., Corradini, R., Ferretti, C., Zanoli, L., Gatti, M., Marchelli, R., Spoto, G.: Ultrasensitive detection of non-amplified genomic DNA by nanoparticle-enhanced surface plasmon resonance imaging. Biosens. Bioelectron. 25, 2095–2100 (2010)
D’Agata, R., Breveglieri, G., Zanoli, L.M., Borgatti, M., Spoto, G., Gambari, R.: Direct detection of point mutations in nonamplified human genomic DNA. Anal. Chem. 83, 8711–8717 (2011)
Mann, T.L., Krull, U.J.: The application of ultrasound as a rapid method to provide DNA fragments suitable for detection by DNA biosensor. Biosens. Bioelectron. 20, 945–955 (2004)
Fang, S., Lee, H.J., Wark, A.W., Corn, R.M.: Attomole microarray detection of MicroRNAs by nanoparticle-amplified SPR imaging measurements of surface polyadenylation reactions. J. Am. Chem. Soc. 128, 14044–14046 (2006)
Wark, A.W., Lee, H.J., Corn, R.M.: Multiplexed detection methods for profiling MicroRNA expression in biological samples. Angew. Chem. Int. Ed. 47, 644–652 (2008)
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D’Agata, R., Spoto, G. (2012). Surface Plasmon Resonance-Based Methods. In: Spoto, G., Corradini, R. (eds) Detection of Non-Amplified Genomic DNA. Soft and Biological Matter. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-1226-3_9
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