Skip to main content
SpringerLink
Log in

Role of Non-Functional Imaging in the Diagnosis of Abdominal Neuroendocrine Tumors

  • Chapter
Abdominal Neuroendocrine Tumors

Part of the book series: Updates in Surgery ((UPDATESSURG))

  • 934 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Sahani DV, Bonaffini PA, Fernandez-Del Castillo C, Blake MA (2013) Gastroenteropancreatic neuroendocrine tumors: role of imaging in diagnosis and management. Radiology 266(1):38–61

    Article  PubMed  Google Scholar 

  2. Orditura M, Petrillo A, Ventriglia J et al (2016) Pancreatic neuroendocrine tumors: nosography, management and treatment. Int J Surg 28(Suppl 1):S156–S162

    Article  PubMed  Google Scholar 

  3. Baumann T, Rottenburger C, Nicolas G, Wild D (2016) Gastroenteropancreatic neuroendocrine tumours (GEP-NET) — Imaging and staging. Best Pract Res Clin Endocrinol Metab 30(1):45–57

    Article  PubMed  Google Scholar 

  4. La Rosa S, Sessa F (eds) (2015) Pancreatic neuroendocrine neoplasms. Practical approach to diagnosis, classification, and therapy. Springer, Cham

    Google Scholar 

  5. Gorman B, Charboneau JW, James EM et al (1986) Benign pancreatic insulinoma: preoperative and intraoperative sonographic localization. AJR Am J Roentgenol 147(5): 929–934

    Article  CAS  PubMed  Google Scholar 

  6. Lewis RB, Lattin GE Jr, Paal E (2010) Pancreatic endocrine tumors: radiologic-clinicopathologic correlation. Radiographics 30(6): 1445–1464

    Article  PubMed  Google Scholar 

  7. Fidler JL Fletcher JG, Reading CC et al (2003) Preoperative detection of pancreatic insulinomas on multiphasic helical CT. AJR Am J Roentgenol 181(3):775–780

    Article  CAS  PubMed  Google Scholar 

  8. Buetow PC, Miller DL, Parrino TV, Buck JL (1997) Islet cell tumors of the pancreas: clinical, radiologic, and pathologic correlation in diagnosis and localization. Radiographics 17(2):453–472

    Article  CAS  PubMed  Google Scholar 

  9. Manta R, Nardi E, Pagano N et al (2016) Pre-operative diagnosis of pancreatic neuroendocrine tumors with endoscopic ultrasonography and computed tomography in a large series. J Gastrointestin Liver Dis 25(3):317–321

    PubMed  Google Scholar 

  10. Sundin A, Vullierme MP, Kaltsas G et al (2009) ENETS Consensus guidelines for the standards of care in neuroendocrine tumors: radiological examinations. Neuroendocrinology 90(2): 167–183

    Article  CAS  PubMed  Google Scholar 

  11. Rockall AG, Reznek RH (2007) Imaging of neuroendocrine tumours (CT/MR/US). Best Pract Res Clin Endocrinol Metab 21(1):43–68

    Article  CAS  PubMed  Google Scholar 

  12. Kitano M, Millo C, Rahbari R et al (2011) Comparison of 6-18F-fluoro-L-DOPA, 18F-2-deoxy-D-glucose, CT, and MRI in patients with pancreatic neuroendocrine neoplasms with von Hippel-Lindau disease. Surgery 150(6): 1122–1128

    Article  PubMed  PubMed Central  Google Scholar 

  13. Lin XZ, Wu ZY, Tao R et al (2012) Dual energy spectral CT imaging of insulinoma - Value in preoperative diagnosis compared with conventional multi-detector CT. Eur J Radiol 81(10):2487–2494

    Article  PubMed  Google Scholar 

  14. Silva AC, Lawder HJ, Hara A et al (2010) Innovations in CT dose reduction strategy: application of the adaptive statistical iterative reconstruction algorithm. AJR Am J Roentgenol 194(1): 191–199

    Article  PubMed  Google Scholar 

  15. Coakley FV, Gould R, Yeh BM, Arenson RL (2011) CT radiation dose: what can you do right now in your practice? AJR Am J Roentgenol 196(3): 619–625

    Article  PubMed  Google Scholar 

  16. Sundin A (2012) Radiological and nuclear medicine imaging of gastroenteropancreatic neuroendocrine tumours. Best Pract Res Clin Gastroenterol 26(6):803–818

    Article  PubMed  Google Scholar 

  17. Langer P, Kann PH, Fendrich V et al (2004) Prospective evaluation of imaging procedures for the detection of pancreaticoduodenal endocrine tumors in patients with multiple endocrine neoplasia type 1. World J Surg 28(12): 1317–1322

    Article  PubMed  Google Scholar 

  18. Rösch T, Lightdale CJ, Botet JF et al (1992) Localization of pancreatic endocrine tumors by endoscopic ultrasonography. N Engl J Med 326(26): 1721–1726

    Article  PubMed  Google Scholar 

  19. Gouya H, Vignaux O, Augui J et al (2003) CT, endoscopic sonography, and a combined protocol for preoperative evaluation of pancreatic insulinomas. AJR Am J Roentgenol 181(4):987–992

    Article  PubMed  Google Scholar 

  20. Zimmer T, Scherübl H, Faiss S et al (2000) Endoscopic ultrasonography of neuroendocrine tumours. Digestion 62(Suppl 1):S45–S50

    Article  Google Scholar 

  21. Anderson MA, Carpenter S, Thompson NW et al (2000) Endoscopic ultrasound is highly accurate and directs management in patients with neuroendocrine tumors of the pancreas. Am J Gastroenterol 95(9):2271–2277

    Article  CAS  PubMed  Google Scholar 

  22. Schumacher B, Lübke HJ, Frieling T et al (1996) Prospective study on the detection of insulinomas by endoscopic ultrasonography. Endoscopy 28(3):273–276

    Article  CAS  PubMed  Google Scholar 

  23. Pais SA, Mcgreevy K, Leblanc JK et al (2007) Utility of EUS-FNA in the diagnosis of pancreatic neuroendocrine tumors: correlation with histopathology in 76 patients. Gastrointest Endosc 65(5):AB304

    Google Scholar 

  24. Doppman JL, Jensen RT (1999) Localization of gastroenteropancreatic tumours by angiography. Ital J Gastroenterol Hepatol 31(Suppl 2):S163–S166

    PubMed  Google Scholar 

  25. Hirose A, Tajima H, Okamoto K et al (2011) A safely resected case of hypervascular pancreatic giant tumor after preoperative arterial embolization. Gan To Kagaku Ryoho 38(12):2451–2453 [Article in Japanese]

    PubMed  Google Scholar 

  26. Ben-Ishay O, Linder R, Ofer A et al (2012) Hypervascular lesion in the head of the pancreas. Preoperative angiography and selective embolization results in bloodless operation. JOP 13(6):671–673

    PubMed  Google Scholar 

  27. Takasaka I, Kawai N, Sato M et al (2012) Preoperative microcoil embolization of the common hepatic artery for pancreatic body cancer. World J Gastroenterol 18(16): 1940–1945

    Article  PubMed  PubMed Central  Google Scholar 

  28. Turaga KK, Kvols LK (2011) Recent progress in the understanding, diagnosis, and treatment of gastroenteropancreatic neuroendocrine tumors. CA Cancer J Clin 61(2): 113–132

    Article  PubMed  Google Scholar 

  29. Garcia-Carbonero R, Garcia-Figueiras R, Carmona-Bayonas A et al; Spanish Cooperative Group of Neuroendocrine Tumors (GETNE) (2015) Imaging approaches to assess the therapeutic response of gastroenteropancreatic neuroendocrine tumors (GEP-NETs): current perspectives and future trends of an exciting field in development. Cancer Metastasis Rev 34(4):823–842

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  30. Kumbasar B, Kamel IR, Tekes A et al (2004) Imaging of neuroendocrine tumors: accuracy of helical CT versus SRS. Abdom Imaging 29(6):696–702

    Article  CAS  PubMed  Google Scholar 

  31. Tan EH, Tan CH (2011) Imaging of gastroenteropancreatic neuroendocrine tumors. World J Clin Oncol 2(1):28–43

    Article  PubMed  PubMed Central  Google Scholar 

  32. Kamaoui I, De-Luca V, Ficarelli S et al (2010) Value of CT enteroclysis in suspected small-bowel carcinoid tumors. AJR Am J Roentgenol 194(3):629–633

    Article  PubMed  Google Scholar 

  33. Ichikawa T, Peterson MS, Federle MP et al (2000) Islet cell tumor of the pancreas: biphasic CT versus MR imaging in tumor detection. Radiology 216(1): 163–171

    Article  CAS  PubMed  Google Scholar 

  34. Pantongrag-Brown L, Buetow PC, Carr NJ et al (1995) Calcification and fibrosis in mesenteric carcinoid tumor: CT findings and pathologic correlation. AJR Am J Roentgenol 164(2):387–391

    Article  CAS  PubMed  Google Scholar 

  35. Rappeport ED, Hansen CP, Kjaer A, Knigge U (2006) Multidetector computed tomography and neuroendocrine pancreaticoduodenal tumors. Acta Radiol 47(3):248–256

    Article  CAS  PubMed  Google Scholar 

  36. Hardie AD, Picard MM, Camp ER et al (2015) Application of an advanced image-based virtual monoenergetic reconstruction of dual source dual-energy CT data at low keV increases image quality for routine pancreas imaging. J Comput Assist Tomogr 39(5):716–720

    Article  PubMed  Google Scholar 

  37. Bader TR, Semelka RC, Chiu VC et al (2001) MRI of carcinoid tumors: spectrum of appearances in the gastrointestinal tract and liver. J Magn Reson Imaging 14(3):261–269

    Article  CAS  PubMed  Google Scholar 

  38. Tamm EP, Kim EE, Ng CS (2007) Imaging of neuroendocrine tumors. Hematol Oncol Clin North Am 21(3):409–132

    Article  PubMed  Google Scholar 

  39. Modlin IM, Oberg K, Chung DC et al (2008) Gastroenteropancreatic neuroendocrine tumours. Lancet Oncol 9(1):61–72

    Article  CAS  PubMed  Google Scholar 

  40. Kavaliauskiene G, Ziech ML, Nio CY, Stoker J (2011) Small bowel MRI in adult patients: not just Crohn’s disease-a tutorial. Insights Imaging 2(5):501–513

    Article  PubMed  PubMed Central  Google Scholar 

  41. Reznek RH (2006) CT/MRI of neuroendocrine tumours. Cancer Imaging 6:S163–S177

    Article  PubMed Central  Google Scholar 

  42. Varas MJ, Gornals JB, Pons C (2010) Usefulness of endoscopic ultrasonography (EUS) for selecting carcinoid tumors as candidates to endoscopic resection. Rev Esp Enferm Dig 102(10):577–582

    Article  CAS  PubMed  Google Scholar 

  43. Modlin IM, Lye KD, Kidd M (2003) A 5-decade analysis of 13,715 carcinoid tumors. Cancer 97(4):934–959

    Article  PubMed  Google Scholar 

  44. Burad DK, Kodiatte TA, Rajeeb SM et al (2016) Neuroendocrine neoplasms of liver — A 5-year retrospective clinico-pathological study applying World Health Organization 2010 classification. World J Gastroenterol 22(40):8956–8966

    Article  PubMed  PubMed Central  Google Scholar 

  45. Gutierrez G, Daniels IR, Garcia A, Ramia JM (2006) Peritoneal carcinomatosis from a small bowel carcinoid tumour. World J Surg Oncol 4:75

    Article  PubMed  PubMed Central  Google Scholar 

  46. Hlatky R, Suki D, Sawaya R (2004) Carcinoid metastasis to the brain. Cancer 101(11): 2605–2613

    Article  PubMed  Google Scholar 

  47. Meijer WG, van der Veer E, Jager PL et al (2003) Bone metastases in carcinoid tumors: clinical features, imaging characteristics, and markers of bone metabolism. J Nucl Med 44(2): 184–191

    PubMed  Google Scholar 

  48. Dromain C, de Baere T, Baudin E et al (2003) MR imaging of hepatic metastases caused by neuroendocrine tumors: comparing four techniques. AJR Am J Roentgenol 180(1): 121–128

    Article  PubMed  Google Scholar 

  49. Gibril F, Jensen RT (2004) Diagnostic uses of radiolabeled somatostatin receptor analogues in gastroenteropancreatic endocrine tumours. Dig Liver Dis 36(Suppl 1):S106–S120

    Article  Google Scholar 

  50. Dromain C, de Baere T, Lumbroso J et al (2005) Detection of liver metastases from endocrine tumors: a prospective comparison of somatostatin receptor scintigraphy, computed tomography, and magnetic resonance imaging. J Clin Oncol 23(1):70–78

    Article  PubMed  Google Scholar 

  51. Bruegel M, Holzapfel K, Gaa J et al (2008) Characterization of focal liver lesions by ADC measurements using a respiratory triggered diffusion-weighted single-shot echo-planar MR imaging technique. Eur Radiol 18(3):477–485

    Article  PubMed  Google Scholar 

  52. Vossen JA, Buijs M, Liapi E et al (2008) Receiver operating characteristic analysis of diffusion-weighted magnetic resonance imaging in differentiating hepatic hemangioma from other hypervascular liver lesions. J Comput Assist Tomogr 32(5):750–756

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Radiological Sciences, Oncological and Pathological Sciences, Sapienza University of Rome — ICOT, Latina, Italy

    Marta Zerunian

Authors
  1. Marta Zerunian
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Davide Bellini
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Andrea Laghi
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Marta Zerunian .

Editor information

Editors and Affiliations

  1. Department of Surgery, Division of General Surgery, S. Eugenio Hospital, Rome, Italy

    Massimo Carlini

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer-Verlag Italia

About this chapter

Cite this chapter

Zerunian, M., Bellini, D., Laghi, A. (2018). Role of Non-Functional Imaging in the Diagnosis of Abdominal Neuroendocrine Tumors. In: Carlini, M. (eds) Abdominal Neuroendocrine Tumors. Updates in Surgery. Springer, Milano. https://doi.org/10.1007/978-88-470-3955-1_7

Download citation

  • DOI: https://doi.org/10.1007/978-88-470-3955-1_7

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-3954-4

  • Online ISBN: 978-88-470-3955-1

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation