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Treatment of Cachexia in the Elderly

  • Chapter
Cachexia and Wasting: A Modern Approach

Abstract

Numerous studies have shown that weight loss is associated with an increase in mortality [1] [4]. Treating weight loss in the elderly can ameliorate many medical conditions. For example, rehabilitation time following post-hip fractures has been shown to decrease with nutritional supplementation [5]. In hospitalised geriatric patients, nutritional supplementation resulted in improvement in serum protein, nutritional status, and decreased mortality [6]. In a subset of geriatric inpatients, low serum albumin with weight loss predicts those patients at highest risk for dying during the subsequent 2 years [7]. Riquelme and Torres et al. [8] carried out a multivariate analysis of risk and prognostic factors in community-acquired pneumonia in the elderly and found that age by itself was not a significant factor related to prognosis. Among the significant risk factors, only nutritional status is amenable to medical intervention. In the cachectic elderly, medical, cognitive, and psychiatric disorders may diminish self-sufficiency in activities of daily living (ADL), thus reducing the quality of life and increasing the frequency of secondary procedures, hospitalisations, and need for skilled care [2, 9].

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Authors and Affiliations

  1. Department of Medicine - Geriatrics, University of New York at Stony Brook VAMC, Northport, NY, USA

    Shing-Shing Yeh

  2. Bone Marrow and Blood Stem Cell Transplantation Program, Center for Lymphoma and Myeloma, New York Presbyterian Hospital/Weill Medical Center, New York, NY, USA

    Michael W. Schuster

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  1. Shing-Shing Yeh
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Editor information

Editors and Affiliations

  1. Department of Medical Oncology, University of Cagliari, Cagliari, Italy

    Giovanni Mantovani

  2. Department of Clinical Cardiology, Imperial College, NHLI, London, UK

    Stefan D. Anker

  3. Department of Cardiology Charité, Applied Cachexia Research, Campus Virchow-Klinikum, Berlin, Germany

    Stefan D. Anker

  4. Department of Behavioral Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan

    Akio Inui

  5. GRECC, VA Medical Center and Division of Geriatric Medicine, Saint Louis University, St. Louis, MO, USA

    John E. Morley

  6. Department of Clinical Medicine, University of Rome, La Sapienza, Rome, Italy

    Filippo Rossi Fanelli

  7. Department of Infectious Diseases, IRCCS S.Matteo Polyclinic, University of Pavia, Pavia, Italy

    Daniele Scevola

  8. Bone Marrow and Blood Stem Cell Transplantation Program, Center for Lymphoma and Myeloma, New York Presbyterian Hospital/Weill Medical Center, New York, NY, USA

    Michael W. Schuster

  9. Department of Medicine-Geriatrics, University of New York at Stony Brook VAMC, Northport, NY, USA

    Shing-Shing Yeh

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Yeh, SS., Schuster, M.W. (2006). Treatment of Cachexia in the Elderly. In: Mantovani, G., et al. Cachexia and Wasting: A Modern Approach. Springer, Milano. https://doi.org/10.1007/978-88-470-0552-5_68

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