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Effects of High Cervical Spinal Cord Stimulation (CSCS) on Regional Cerebral Blood Flow after Induced Subatachnoid Haemorrhage in Rats

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Cerebral Vasospasm

Part of the book series: Acta Neurochirurgica Supplements ((NEUROCHIRURGICA,volume 77))

Abstract

Cerebral vasospasm is the most frequent cause of morbidity and mortality in patients after SAH. The direct measurement of regional cerebral blood flow (rCBF) is a valuable adjunct for monitoring SAH patients. Single photon emission computed tomography (SPECT) with 99mTc-HMPAO is an adequate technique for the measurement of CBF [9, 10]. It measures the net effect of vasospasm on cerebral perfusion. 99mTc-HMPAO is a radioactive agent crossing the blood-brain barrier. It is trapped within the brain with flow-dependent distribution. Decreased cerebral uptake of 99mTc-HMPAO in cerebrovascular disease has been shown to correspond well with the results of other methods [3]. Despite a wide variety of treatment modalities no definitive treatment prevents vasospasm. Spinal cord stimulation (SCS) has been accepted to improve microcirculatory parameters in patients with critical limb ischemia [1]. Furthermore, it was proven that cervical spinal cord stimulation increases cerebral blood flow in normal conditions [4].

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© 2001 Springer-Verlag

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Ebel, H. et al. (2001). Effects of High Cervical Spinal Cord Stimulation (CSCS) on Regional Cerebral Blood Flow after Induced Subatachnoid Haemorrhage in Rats. In: Seiler, R.W., Steiger, HJ. (eds) Cerebral Vasospasm. Acta Neurochirurgica Supplements, vol 77. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6232-3_48

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  • DOI: https://doi.org/10.1007/978-3-7091-6232-3_48

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-211-83650-7

  • Online ISBN: 978-3-7091-6232-3

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