Abstract
Magnetic nanoparticles (MNPs) – especially single-domain-based superparamagnetic (SPM) nanoparticles in ferrofluid form – are primarily utilized in magnetic fluid hyperthermia (MFH)-based thermotherapy for cancer treatment applications due to their following advantages: (i) unique magnetic properties, (ii) better chemical stability, and (iii) high cytocompatibility. In MFH therapy, the cancer cells are quickly heated to the therapeutic temperatures of ~42–45 °C using the MNPs on exposure to externally applied alternating magnetic fields (AMFs), where the induced heat might damage the consequent proliferation of cancer cells by promoting apoptosis/mitotic death and thus preventing the tumor growth.
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Maity, D., Kandasamy, G. (2019). Superparamagnetic Nanoparticles for Cancer Hyperthermia Treatment. In: Kumar, C. (eds) Nanotechnology Characterization Tools for Tissue Engineering and Medical Therapy. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-59596-1_7
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