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Mammakarzinom bei der alten und geriatrischen Patientin

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Zusammenfassung

Die moderne Mammakarzinomtherapie basiert auf den Säulen lokoregionäre und systemische Therapie, wobei die individuellen Therapiekonzepte idealerweise im interdisziplinären Tumorboard festgelegt werden. In Deutschland bilden die jährlich aktualisierten AGO-Empfehlungen die Grundlage des Vorgehens bei älteren Patientinnen. Generell ist das kalendarische Alter allein kein ausreichender Grund, auf eine leitliniengerechte Therapie zu verzichten. Bei der Therapieplanung sollten die Therapieziele berücksichtigt werden. Während das frühe Mammakarzinom ohne Fernmetastasen mit kurativer Intention behandelt wird, stehen bei der metastasierten Erkrankung Symptomkontrolle und Erhalt der Lebensqualität im Vordergrund. Da sich individuelle Komorbiditäten und Lebenserwartung bei älteren Patientinnen sehr unterscheiden können, sind generalisierte Therapieempfehlungen schwierig. Eine individualisierte Therapieführung ist dennoch evidenzbasiert möglich.

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  1. Brustzentrum der Universität München, Marchioninistr. 15, 81377, München, Deutschland

    Nadia Harbeck, Rachel Würstlein & Maximiliane Burgmann

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  2. Rachel Würstlein
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Correspondence to Nadia Harbeck .

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  1. II. Medizinische Klinik, Universitätsmedizin Mannheim, Mannheim, Germany

    Matthias Ebert

  2. II. Medizinische Klinik, Universitätsmedizin Mannheim, Mannheim, Germany

    Nicolai Härtel

  3. Klinik für Innere Medizin II, Universitätsklinikum Jena, Jena, Germany

    Ulrich Wedding

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  1. Interdisziplinäres Tumorzentrum, Universitätsmedizin Mannheim, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Deutschland

    Nicolai Härtel

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Harbeck, N., Würstlein, R., Burgmann, M. (2018). Mammakarzinom bei der alten und geriatrischen Patientin. In: Ebert, M., Härtel, N., Wedding, U. (eds) Geriatrische Onkologie. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-48727-3_31

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