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Gender Differences in Skin

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Abstract

Genetic differences between men and women are the cause of many phenotypic and functional differences. In addition, men and women generally lead different lifestyles. How this affects various aspects of aging skin is an extensive area of study. Analyzing gender’s influence in characteristics of the skin, including structural and anatomical characteristics, biochemical composition, mechanical properties, and skin color, has been a primary topic. Homeostatic and functional variations such as in sweat rate, blood flow, pH, sensory response, response to irritants, and reparative abilities affect the integrity of the skin. In addition, there are many hormone-dependent mechanisms related to the skin, thereby suggesting sex-based differences of these mechanisms. Seasonal variation, also, alters skin physiology. Taken together, research suggests gender does, indeed, affect skin properties. However, some studies report no difference or contradicting results. This is likely due to varied experimental designs. Thus, emphasis should be placed on maintaining standard methods for results to be comparable and taking note of parameters such as types of population, age, lifestyle, and environment. Overall, elucidating which aspects of aging skin are affected and how they are affected will improve sex-specific approaches toward skin care treatment.

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Phuong, C., Maibach, H.I. (2017). Gender Differences in Skin. In: Farage, M., Miller, K., Maibach, H. (eds) Textbook of Aging Skin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-47398-6_93

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