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Calmodulin and Calmodulin-Binding Proteins in the Cell Nucleus

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Book cover Calcium and Calmodulin Function in the Cell Nucleus

Part of the book series: Molecular Biology Intelligence Unit ((MBIU))

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Abstract

calmodulin (CaM) is the major calcium-binding protein in all the eukaryotic cells with the exception of skeletal and cardiac muscle. CaM has a Mr around 16 kDa and in higher eukaryotic cells it is encoded by three different genes (CaMI, CaMII and CaMIII) which in spite of displaying different structure and nucleotide sequence, specially in the 5′ and 3′ terminal sequences, all of them encode for exactly the same protein. In yeast and other fungi, only one gene encoding for CaM has been identified. The amino acid sequence of CaM from all the mammalian cells is exactly the same and the homology with CaM from the other eukaryotic species is also very high.

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  1. University of Barcelona, Barcelona, Spain

    Oriol Bachs Ph.D. & Neus Agell Ph.D.

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Bachs, O., Agell, N. (1995). Calmodulin and Calmodulin-Binding Proteins in the Cell Nucleus. In: Calcium and Calmodulin Function in the Cell Nucleus. Molecular Biology Intelligence Unit. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-21686-6_5

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  • DOI: https://doi.org/10.1007/978-3-662-21686-6_5

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