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Regional Cerebral Blood Flow in Transient Ischaemic Attacks, Effects of Reconstructive Vascular Surgery — A Study Using Xenon-133 Inhalation and Single-Photon Tomography

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Modern Neurosurgery 1

Abstract

Regional cerebral blood flow (rCBF) was studied tomographically with 133-Xenon administered by inhalation over 1-min-period at a concentration of 10 mCi/l. A fast rotating (“dynamic”) single-photon emission computed tomograph with four detector heads was used, an instrument that has been found to be well suited for detecting focal ischaemia.

In the present study the method was applied to a series of 12 patients with transient ischaemia attacks from the carotid territory which occurred days or weeks before the CBF study. Asymmetry of the CBF tomograms exceeding the normal limits was found in all 12 cases. In all but one severe stenosed or occluded internal carotid artery was found on the low flow side; the twelfth case had low grade stenosis and the flow asymmetry was probably accounted for by a CT-proven brain atrophy.

Tomographic CBF studies are considered essential in surgical management of TIA cases. The method presented is discussed relative to alternative approaches based on X-ray tomography and on positron tomography.

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© 1982 Springer-Verlag Berlin Heidelberg

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Lassen, N.A., Henriksen, L., Hemmingsen, R., Vorstrup, S. (1982). Regional Cerebral Blood Flow in Transient Ischaemic Attacks, Effects of Reconstructive Vascular Surgery — A Study Using Xenon-133 Inhalation and Single-Photon Tomography. In: Brock, M. (eds) Modern Neurosurgery 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-08801-2_40

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  • DOI: https://doi.org/10.1007/978-3-662-08801-2_40

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-08803-6

  • Online ISBN: 978-3-662-08801-2

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