Abstract
In 1768, William Young, the royal botanist, imported living plants of the Venus fly-trap to England. They were shown to John Ellis, a member of the Royal Society, who recognised the Venus as a carnivorous plant. He wrote a letter and sent it with a dried plant to the Swedish scientist, Carl von Linné. Among others Ellis wrote: “Nature may have some views towards its nourishment in forming the upper joint of its leaf like a machine to catch food: upon the middle of this lies the bait for the unhappy insect that becomes its prey . .. the two lobes rise up, grasp it fast, lock the rows of spines together, and squeeze it to death ... the small erect spines are fixed near the middle of each lobe, over the glands, that effectually put an end to all its struggles”. Linné gave this species the name Dionaea muscipula Ellis (Slack 1985; Juniper et al. 1989). This name comes from the Greek word Dionaia, the goddess of love.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Ahn D, Putt D, Kresty L, Stoner GD, Fromm D, Hollenberg PF (1996) The effects of dietary ellagic acid on rat hepatic and esophageal mucosal cytochrome P450 and phase II enzymes. Carcinogenesis 17:821–828
Bhattacharayya J, Kokpol U, Miles DH (1976) The isolation from Sarracenia flava and partial synthesis of betulinaldehyde. Phytochemistry 15:432–433
Beebe JD (1980) Morphogenetic responses of seedlings and adventitious buds of the carnivorous plant Dionaea muscipula in aseptic culture. Bot Gaz 141:396–400
Budzianowski J (1995) Naphthoquinones of Drosera spathulata from in vitro cultures. Phytochemistry 40:1145–1148
Budzianowski J (1996) Naphthohydroquinone glucosides of Drosera rotundifolia and D. intermedia from in vitro cultures. Phytochemistry 42:1145–1147
Budzianowski J(1997) 2-Methyl naphthazarin 5-O-glucoside from the methanolic extracts of in vitro cultures of Drosera species. Phytochemistry 44:75–77
Budzianowski J (2000) Naphthoquinone glucosides of Drosera gigantea from in vitro cultures. Planta Med 66:667–669
Budzianowski J, Pakulski G, Skrzypczak L (1993a) Ellagic acid derivatives and further naphthoquinones from Dionaea muscipula and four species of the genus Drosera from in vitro cultures. 41th Annu Congr Med Plant Res, 31 August-4 September 1993, Düsseldorf, Abstr, p 79. Planta Med 59 (Suppl A 654)
Budzianowski J, Skrzypczak L, Kukulczanka K (1993b) Phenolic compounds of Drosera intermedia and D. spathulata from in vitro cultures. Acta Hortic 330:277–280
Budzianowski J, Pakulski G, Skrzypczak L (1995) Phenolic metabolites of Droseraceae species from in vitro cultures. 43th Annu Congr Med Plant Res, Halle (Saale), Abstr, p 34
Budzianowski J, Ratajczak L, Skrzypczak L (1996) Flavonoids of Droseraceae species from in vitro cultures. 44th Annu Congr Med Plant Res, Prague, Abstr, p 140
Budzianowski J, Ratajczak L, Kromer K (1998) Phenolic compounds in further species of the genus Drosera L. from in vitro cultures. 46th Annu Congr Med Plant Res, 30 August-4 September 1998, Vienna, Abstr, p C19
Crouch IJ, Finnie JF, van Staden J (1990) Studies on the isolation of plumbagin from in vitro and in vivo grown Drosera species. Plant Cell Tissue Organ Cult 21:79–82
Culham A, Gornall RJ (1994) The taxonomic significance of naphthoquinones in the Droseraceae. Biochem Syst Ecol 22:507–515
Di Gregorio GJ, Di Palma JR (1966) Anthocyanin in Dionaea muscipula Ellis (Venus’s flytrap) Nature (Lond) 212:1264–1265
Dietzel U, Sauer R, Reichardt U (1985) Erfahrungen mit Carnivora. Fortschr Med 103:760–781
Drees M, Berger DP, Dengler WA, Fiebig GH (1996) Direct cytotoxic effects of preparations used as unconventional methods in the clonogenic assay and in nude mice. Contrib Oncol 51:115–122;
Drees M, Berger DP, Dengler WA, Fiebig GH (1996) Direct cytotoxic effects of preparations used as unconventional methods in the clonogenic assay and in nude mice. Chem Abstr 1996 125:75628u
Encke F (1958) Dionaea L. In: Encke F (ed) Pareys Blumengärtnerei, vol 1, 2nd edn. Paul Parey, Berlin, pp 713–714
Finnie JF, van Staden J (1993) Drosera spp. (Sundew): micropropagation and the in vitro production of plumbagin. In: Bajaj YPS (ed) Biotechnology in agriculture and forestry, vol 24. Medicinal and aromatic plants V. Springer, Berlin Heidelberg New York, pp 164–177
Fujii N, Yamashita Y, Arima Y, Nagashima M, Nakano H (1992) Induction of topoisomerase IImediated DNA cleavage by the plant naphthoquinones plumbagin and shikonin. Antimicrob Agents Chemother 36:2589–2594
Galek H, Osswald WF, Elstner EF (1990) Oxidative protein modification as predigestive mechanism of the carnivorous plant Dionaea muscipula: an hypothesis based on in vitro experiments. Free Radical Biol Med 9:427–434
Gershbein LL, Brown MF, Hoepsch JP, Young DC (1995) Sterol composition and distribution in carnivorous plants, Sarracenia flava, Sarracenia purpurea and Dionaea muscipula. Trans Ill Acad Sci 88:13–20;
Gershbein LL, Brown MF, Hoepsch JP, Young DC (1995) Sterol composition and distribution in carnivorous plants, Sarracenia flava, Sarracenia purpurea and Dionaea muscipula. Chem Abstr 1995 123:52269x
Gujar GT (1990) Plumbagin, a naturally occurring naphtoquinone. Its pharmacological and pesticidal activity. Fitoterapia 61:387–394
Hamlet EH (1995) Dionaea. In: Cullen J, Alexander JCM, Brady A (eds) The European garden flora, vol 4, part 2. Dicotyledons. Cambridge Univ Press, Cambridge, p 88
Hauser SP (1988) Carnivora — Phytotherapeuticum zur Behandlung maligner Erkrankungen. Schweiz Rundsch Med (PRAXIS) 77:283–287
Hegnauer R (1989) Chemotaxonomie der Pflanzen, vol 8. Birkhäuser, Basel
Hegnauer R (1990) Chemotaxonomie der Pflanzen, vol 9. Birkhäuser, Basel
Hodick D, Sievers A (1986) The influence of Ca2+ on the action potentials in mesophyll cells of Dionaea muscipula Ellis. Protoplasma 133:83–84
Hodick D, Sievers A (1989) Action potentials of Dionaea muscipula Ellis. Planta 179:32–34
Hutchinson JF (1984) In vitro propagation of Dionaea muscipula Ellis (Venus fly trap). Sci Hortic 22:189–194
Ichiishi S, Nagamitsu T, Kondo Y, Iwashina T, Kondo K, Tagashira N (1999) Effects of macrocomponents and sucrose in the medium on in vitro red-color pigmentation in Dionaea muscipula Ellis and Drosera spathulata Labill. Plant Biotechnol (Tokyo) 16 (3):235–238
Jay M, Lebreton P (1972) Chemotaxonomic research on vascular plants 26. The flavonoids of Sarraceniaceae, Nepenthaceae, Droseraceae and Cephalotaceae, a critical study of the order Sarraceniales. Nat Canadienne 99:607–613
Josephy PD, Snieckus VA (1992) Ellagic acid and synthetic analogs as inhibitors of mutagenesis and carcinogenesis. Cell Mol Targets Chemoprev 1992:147–160
Juniper BE, Robins RJ, Joel DM (1989) The carnivorous plants. Academic Press, London
Keller H (1987) Pharmaceutical containing the digestive juices of carnivorous plants for treatment of malignant and chronic diseases. Ger Offen DE 1987 3:619;
Keller H (1987) Pharmaceutical containing the digestive juices of carnivorous plants for treatment of malignant and chronic diseases. Chem Abstr 1988 109:79697h
Kreher B, Neszmelyi A, Polos K, Wagner H (1988a) Structure elucidation of plumbagin-analogues from Dionaea muscipula and their in vitro immuno-modulating activities in vitro and in vivo. Proc Int Symp Hungarian Chem Soc, Sopron (Hungary) 24–27.06.88, pp 1–16
Kreher B, Neszmelyi A, Polos K, Wagner H (1988b) Structure elucidation of plumbagin analogues from Dionaea muscipula and their in vitro immunological activity on human granulocytes and lymphocytes. 36th Annu Congr Med Plant Res, Freiburg, Abstr, p 45
Kreher B, Neszmelyi A, Wagner H (1990) Naphthoquinones from Dionaea muscipula. Phytochemistry 29:605–606
Kukułczanka K (1991) Micropropagation and in vitro germplasm storage of Droseraceae. Bot Gard Micropropagation News 1:38–42
Kukulczanka K, Czḁstka B (1987) Propagation of Drosera L. in vitro conditions, Wiad Bot Biul Ogrodów Bot 31:61–64
Kukułczanka K, Czastka B (1991) Vegetative propagation of selected species of Droseraceae taxa and in vitro gene bank establishment. Prace Ogr Bot PAN 1:55–61
Kukułczanka K, Czḁstka B, Arczewska A (1989) Regeneration from leaves of Dionaea muscipula Ellis cultured in vitro. Acta Hortic 251:155–160
Kukułczanka K, Kromer K, Klonowska B, Czastka B (1991) The temperature effect on the preservation of the plant cultures of Droseraceae in vitro. Prace Ogr Bot PAN 1:63–68
Linsmaier EM, Skoog F (1965) Organic growth factor requirements of tobacco tissue cultures. Physiol Plant 18:100–127
Lloyd FE (1942) The carnivorous plants. Chronica Botanica. Waltham, MA, USA, pp 177–194
Miles DH, Kokpol U, Bhattacharayya J, Attwood JL, Stone KE, Bryson TA, Wilson C (1976) Structure of sarracenin. An unusual enol diacetal monoterpene from the insectivorous plant Sarracenia flava. J Am Chem Soc 98:1569–1573
Miyoshi E, Shizuri Y, Yamamura S (1984) Isolation and structures of diomuscinone and diomuscipulone from Dionaea muscipula. Phytochemistry 23:2385–2387
Murashige T, Skoog F (1962) A revised medium for rapid growth and bio-assays with tobacco cultures. Physiol Plant 15:473–497
Pakulski G (1994) Zwiazki fenolowe z gatunku Dionaea muscipula Ellis pochodzḁcego z kultur in vitro. (Phenolic compounds from the species Dionaea muscipula Ellis of in vitro culture origin) Dissertation, Faculty of Pharmacy, K.Marcinkowski University of Medical Sciences, Poznań
Pakulski G, Budzianowski J (1996a) Ellagic acid derivatives and naphthoquinones of Dionaea muscipula from in vitro cultures. Phytochemistry 41:775–778
Pakulski G, Budzianowski J (1996b) Flavonoids of Dionaea muscipula from in vitro cultures. Planta Med 62:95–96
Parliman BJ, Evans PT, Rupert EA (1982a) Tissue culture of single rhizome explants of Dionaea muscipula Ellis ex L., the Venus fly-trap, for rapid asexual propagation. J Am Soc Hortic Sci 107 (2):305–310
Parliman RJ, Evans PT, Mazur AR (1982b) Adventitious bud differentiation and development in leaf cuttings of Dionaea muscipula Ellis ex L. (Venus fly-trap) cultured in vitro. J Am Soc Hortic Sci 107 (2):310–316
Ragazzi E, de Biasi M, Pandolfo L, Chinellato A, Caparrotta L (1993) In vitro effects of naphthoquinones isolated from Drosera species. Pharmacol Res 27(Suppl 1):87–88
Reinert RA, Mohr HC (1967) Propagation of Cattleya by tissue culture of lateral bud meristems. Proc Am Soc Hortic 91:664–671
Rote Liste (2000) Verzeichnis von Fertigarzneimitteln der Mitglieder des Bundesverbandes der Pharmazeutischen Industrie. Cantor, Aulendorf
Samaj J, Blehová A, Repčák M, Ovečka M, Bobák M (1999) Drosera species (Sundew): in vitro culture and the production of plumbagin and other secondary metabolites. In: Bajaj YPS (ed) Biotechnology in agriculture and forestry, vol 43. Medicinal and aromatic plants XI. Springer, Berlin Heidelberg New York, pp 105–135
Sampara-Rumantir N (1971) Rossoliside. Pharm Weekbl 106:653–664
Shanhinpoor M, Thompson MS (1995) The Venus flytrap as a model for a biomimetic material with built-in sensor and actuations. Mater Sci Eng C C2:229–233;
Shanhinpoor M, Thompson MS (1995) The Venus flytrap as a model for a biomimetic material with built-in sensor and actuations. Chem Abstr 1996 124:6160r
Slack A (1985) Karnivoren: Biologie und Kultur der Insektenfangenden Pflanzen. Ulmer, Stuttgart, pp 243–245 (15–19), 167–173
Teng WL (1999) Source, etiolation and orientation of explants affect in vitro regeneration of venus fly-trap (Dionaea muscipula). Plant Cell Rep 18:363–368
Todorov DK, Ilarianova MV (1996) Antitumor activity of the Dionaea muscipula Ellis. Preparation Carnivora New in vitro and in vivo on several animal and human tumors, sensitive and resistant to antitumor drugs. Carnivora-Forschungs GmbH Nordhalben Firm’s Information
Todorov DK, Ilarianova MV, Maneva K (1995a) Antiproliferative activity of Carnivora on two human glioma cell lines. Carnivora-Forschungs GmbH Nordhalben Firm’s Information
Todorov DK, Ilarianova MV, Maneva K (1995b) Antiproliferative activity of Carnivora on multidrug-resistant sarcoma 180/dox constant tumor cell line. Carnivora-Forschungs GmbH Nordhalben Firm’s Information
Todorov DK, Ilarianova MV, Maneva K (1996a) Experimental studies on the antiproliferative activity of Carnivora on human leukemic CEM cell line — multidrug-resistant (MDR). Carnivora-Forschungs GmbH Nordhalben Firm’s Information
Todorov DK, Ilarianova MV, Maneva K (1996b) Experimental studies on the antiproliferative activity of Carnivora on human leukemic CEM cell line — multidrug-resistant (MDR). Carnivora-Forschungs GmbH Nordhalben Firm’s Information
Todorov DK, Ilarionowa MV, Timcheva KB, Pajeva IK (1998) Antitumor activity of Dionaea muscipula E. preparation Carnivora in animal and human tumors sensitive and resistant to antitumor drugs. Biotechnol Biotechnol Equip 1998 (2):61–66
Trebacz K, Sievers A (1998) Action potentials evoked by light in traps of Dionaea muscipula Ellis. Plant Cell Physiol 39:369–372
Trebacz K, Bush MB, Hejnowicz Z, Sievers A (1996) Cydopiazonic acid disturbs the regulation of cytosolic calcium when repetitive action potentials are evoked in Dionaea traps. Planta 198:623–626
Vinkeborg J, Sampara-Rumantir N, Uffielie OF (1969) Presence of hydroplumbagin glucoside in Drosera rotundifolia. Pharm Weekbl 104:45–49
Vinkeborg J, Sampara-Rumantir N, Uffelie OF (1970) Rossoliside, a glucoside from Drosera rotundifolia L. Pharm Weekbl 105:414
Wagner H, Kreher B, Jurcic K (1986) Immunological investigations of naphthoquinone containing plant extracts, isolated quinones and other cytostatic compounds in cellular immunosystems. 34th Annu Congr on Med Plant Res, Hamburg, Germany, Abstr, pp 69–70
Wagner H, Kreher B, Jurcic K (1988) In vitro stimulation of human granulocytes and lymphocytes by pico and femtogram quantities of cytostatic agents. Arzneim-Forsch Drug Res 38:273–275
Wurm G, Grimm H, Geres U, Schmidt H (1984) Plumbagin: Reaktivität, toxicität und mikrobielle aktivität des in Drosera und Plumbago arten vorkommenden. Dtsch Apoth Ztg 124:2128–2132
Zenk MH, Fürbringer M, Steglich W (1969) Occurence and distribution of 7-methyljuglone and plumbagin in the Droseraceae. Phytochemistry 8:2199–2200
Zimmerman RH, Broome OC (1980) Blueberry micropropagation. Proc Conf Nursey Culture — Applications and Feasibility, 21–22 April 1980, Beltsville, USA, pp 44–47
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2002 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Kukułczanka, K., Budzianowski, J. (2002). Dionaea muscipula Ellis (Venus Flytrap): In Vitro Cultures and in Vitro Production of Secondary Metabolites. In: Nagata, T., Ebizuka, Y. (eds) Medicinal and Aromatic Plants XII. Biotechnology in Agriculture and Forestry, vol 51. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-08616-2_4
Download citation
DOI: https://doi.org/10.1007/978-3-662-08616-2_4
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-07503-2
Online ISBN: 978-3-662-08616-2
eBook Packages: Springer Book Archive